Výsledky vyhledávání - "Nektaria Simiantonaki"

Function and mutual interaction of BiP-, PERK-, and IRE1α-dependent signalling pathways in vascular tumours

Autor: Caren Jayasinghe, Roman Tsaryk, Felicitas Pröls, Larissa Seidmann, Laura Anspach, C. James Kirkpatrick, Ronald E. Unger, Nektaria Simiantonaki

Publikováno v: The Journal of pathologyReferences. 251(2)

Spontaneously regressing infantile haemangiomas and aggressive angiosarcomas are vascular tumours with excessive angiogenesis. When analysing haemangiomas and angiosarcomas immunohistochemically with respect to their chaperone profiles we found that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60174b82db8f96ddd3ed9260bcbae567
https://pubmed.ncbi.nlm.nih.gov/32166747

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Pulmonary histiocytic sarcoma mimicking pulmonary Langerhans cell histiocytosis in a young adult presenting with spontaneous pneumothorax: a potential diagnostic pitfall

Autor: Elvira Stacher, Helmut Popper, Christine Beham-Schmid, Hans-Joachim Terpe, Nektaria Simiantonaki

Publikováno v: Virchows Archiv. 455:187-190

We present a case of a histiocytic sarcoma incidentally detected in peripheral lung tissue resected for a spontaneous pneumothorax. Furthermore, we discuss the practical approach to pulmonary Langerhans cell histiocytosis, the main differential diagn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0e6824b7a367dc671d261a78fde663
https://doi.org/10.1007/s00428-009-0801-3

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Cell type- and tumor zone-specific expression of pVEGFR-1 and its ligands influence colon cancer metastasis

Autor: Caren Jayasinghe, Nektaria Simiantonaki, Charles James Kirkpatrick

Publikováno v: BMC Cancer

Background Detailed knowledge of the essential pro-angiogenic biomolecules, the vascular endothelial growth factor (VEGF) family and its receptors, in the characteristically heterogeneous tumor tissue is a pre-requisite for an effective personalized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18929c8c97e4ba190f7064e3a68c9087
https://doi.org/10.1186/s12885-015-1130-3

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The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer

Autor: Sylvia Habedank, Nektaria Simiantonaki, Charles James Kirkpatrick, Caren Jayasinghe

Publikováno v: Journal of Experimental & Clinical Cancer Research : CR

Background For the successful therapeutic use of inhibitors of the vascular endothelial growth factor receptor (VEGFR) pathway detailed knowledge of the mechanisms leading to tumor progression is indispensable. The main goal of this study was to dete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce1e3283a8969b8c4bac6b1a62405da
https://pubmed.ncbi.nlm.nih.gov/25967108

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Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4

Autor: Thomas Wehler, A Müller, Ines Gockel, Theodor Junginger, Nektaria Simiantonaki, V. Hörner, T. Achenbach, Markus Moehler, Peter R. Galle, Martin Schuler, Andreas Teufel, R. Bahre, Stefan Biesterfeld, K Frerichs, Carl C. Schimanski

Publikováno v: British Journal of Cancer

In different tumour entities, expression of the chemokine receptor 4 (CXCR4) has been linked to tumour dissemination and poor prognosis. Therefore, we evaluated, if the expression of CXCR4 exerts similar effects in human hepatocellular carcinoma (HCC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c0ad5e6d31b03a1a1ea6c9ccce6647
https://doi.org/10.1038/sj.bjc.6603251

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Effect of Chemokine Receptors CXCR4 and CCR7 on the Metastatic Behavior of Human Colorectal Cancer

Autor: Vanessa Wilsberg, Markus Moehler, Martin R. Berger, Stefan Schwald, Peter R. Galle, Ursula Gönner, Theodor Junginger, Nektaria Simiantonaki, Caren Jayasinghe, Carl C. Schimanski

Publikováno v: Clinical Cancer Research. 11:1743-1750

Purpose: The expression of chemokine receptors CXCR4 and CCR7 has been associated with tumor dissemination and poor prognosis in a limited number of tumor entities. However, no data are currently available on the impact of chemokine receptor expressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6e362c3a4e7319e8ee2aa5201b2632
https://doi.org/10.1158/1078-0432.ccr-04-1195

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Local staging of rectal carcinoma and assessment of the circumferential resection margin with high-resolution MRI using an integrated parallel acquisition technique

Autor: Manfred Thelen, Nektaria Simiantonaki, Frank Krummenauer, Theodor Junginger, Susan Trouet, Karl-F. Kreitner, Katja Oberholzer

Publikováno v: Journal of Magnetic Resonance Imaging. 22:101-108

Purpose To assess the diagnostic accuracy of integrated parallel acquisition technique (iPAT) in local staging of rectal carcinoma in comparison to conventional high-resolution MRI. Materials and Methods A total of 28 patients with a neoplasm of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3d0bb57db248eb0bf839359660e451
https://doi.org/10.1002/jmri.20347

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