Reduced Volume and Faster Infusion Rate of Activated Prothrombin Complex Concentrate: A Phase 3b/4 Trial in Adults with Hemophilia A with Inhibitors.

Autor: Zülfikar B; Hereditary Bleeding Disorders Unit in Oncology Institute, Istanbul University, Istanbul, Turkey., Mahlangu J; Department of Molecular Medicine and Haematology, Faculty of Health Sciences, University of the Witwatersrand and NHLS, Johannesburg, South Africa., Nekkal SM; CHU Isaad Hassani, Beni Messous, Algiers, Algeria., Ross C; St John's Medical College Hospital, Bangalore, India., Uaprasert N; Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.; Center of Excellence in Translational Hematology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand., Windyga J; Department of Hemostasis Disorders and Internal Medicine, Laboratory of Hemostasis and Metabolic Diseases, Institute of Hematology and Transfusion Medicine, Warsaw, Poland., Ettingshausen CE; Haemophilia Centre Rhein Main, Frankfurt-Mörfelden, Germany., Ploder B; Baxalta Innovations GmbH, a Takeda company, Vienna, Austria., Lelli A; PDT R&D Global Medical Affairs, Takeda Pharmaceuticals International AG, Zurich, Switzerland., Gazda HT; Takeda Development Center Americas, Inc., Cambridge, Massachusetts, United States.

Publikováno v: TH open : companion journal to thrombosis and haemostasis [TH Open] 2024 Jul 08; Vol. 8 (3), pp. e273-e282. Date of Electronic Publication: 2024 Jul 08 (Print Publication: 2024).