Valence-dependent dopaminergic modulation during reversal learning in Parkinson's disease: A neurocomputational approach.

Autor: Ursino M; Department of Electrical, Electronic and Information Engineering Guglielmo Marconi, University of Bologna, Campus of Cesena, I 47521 Cesena, Italy. Electronic address: mauro.ursino@unibo.it., Pelle S; Department of Electrical, Electronic and Information Engineering Guglielmo Marconi, University of Bologna, Campus of Cesena, I 47521 Cesena, Italy. Electronic address: silvana.pelle3@unibo.it., Nekka F; Faculté de Pharmacie, Université de Montréal, Montreal, Quebec H3T 1J4, Canada; Centre de recherches mathématiques, Université de Montréal, Montreal, Quebec H3T 1J4, Canada; Centre for Applied Mathematics in Bioscience and Medicine (CAMBAM), McGill University, Montreal, Quebec H3G 1Y6, Canada. Electronic address: fahima.nekka@umontreal.ca., Robaey P; Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada. Electronic address: philippe.robaey@umontreal.ca., Schirru M; Department of Electrical, Electronic and Information Engineering Guglielmo Marconi, University of Bologna, Campus of Cesena, I 47521 Cesena, Italy; Faculté de Pharmacie, Université de Montréal, Montreal, Quebec H3T 1J4, Canada. Electronic address: miriam.schirru@umontreal.ca.

Publikováno v: Neurobiology of learning and memory [Neurobiol Learn Mem] 2024 Nov; Vol. 215, pp. 107985. Date of Electronic Publication: 2024 Sep 11.

An exploratory analysis of the performance of methylphenidate regimens based on a PKPD model of dopamine and norepinephrine transporter occupancy.

Autor: Soufsaf S; Université de Montréal, Montréal, QC, Canada. sara.soufsaf@umontreal.ca., Robaey P; University of Ottawa, Ottawa, ON, Canada., Nekka F; Université de Montréal, Montréal, QC, Canada.

Publikováno v: Journal of pharmacokinetics and pharmacodynamics [J Pharmacokinet Pharmacodyn] 2023 Aug; Vol. 50 (4), pp. 267-281. Date of Electronic Publication: 2023 Mar 17.

Understanding the Mechanisms and Treatment of Heart Failure: Quantitative Systems Pharmacology Models with a Focus on SGLT2 Inhibitors and Sex-Specific Differences.

Autor: Ndiaye JF; Department of Mathematics and Statistics, Université de Montréal, Montréal, QC H3C 3J7, Canada.; Sainte-Justine University Hospital Research Centre, Montréal, QC H3T 1C5, Canada., Nekka F; Faculty of Pharmacy, Université de Montréal, Montréal, QC H3C 3J7, Canada., Craig M; Department of Mathematics and Statistics, Université de Montréal, Montréal, QC H3C 3J7, Canada.; Sainte-Justine University Hospital Research Centre, Montréal, QC H3T 1C5, Canada.

Publikováno v: Pharmaceutics [Pharmaceutics] 2023 Mar 20; Vol. 15 (3). Date of Electronic Publication: 2023 Mar 20.

A Mathematical Model to Predict HIV Virological Failure and Elucidate the Role of Lymph Node Drug Penetration

Autor: Sanche, S, Sheehan, N, Mesplède, T, Wainberg, MA, Li, J, Nekka, F

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology

Preventing virological failure following HIV treatment remains a difficult task that is further complicated by the emergence of drug resistance. We have developed a mathematical model able to explain and predict HIV virological outcomes for various c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::009036596757075d7c6b0d08b997f6f0
http://europepmc.org/articles/PMC5706346

Trapezoid bioequivalence: A rational bioavailability evaluation approach on account of the pharmaceutical-driven balance of population average and variability.

Autor: Soufsaf S; Université de Montréal, Montréal, Québec, Canada., Nekka F; Université de Montréal, Montréal, Québec, Canada., Li J; Université de Montréal, Montréal, Québec, Canada.

Publikováno v: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2022 Apr; Vol. 11 (4), pp. 482-493. Date of Electronic Publication: 2022 Mar 18.