Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nekeithia S. Wade"'
Autor:
Christine M Coquery, Nekeithia S Wade, William M Loo, Jason M Kinchen, Kelly M Cox, Chao Jiang, Kenneth S Tung, Loren D Erickson
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102284 (2014)
Despite increased frequencies of neutrophils found in autoimmune diseases such as systemic lupus erythematosus (SLE), how they contribute to disease pathogenesis and the mechanisms that affect the accumulation of neutrophils are poorly understood. Th
Externí odkaz:
https://doaj.org/article/f818285b96e1412a90116d868c20fa6d
Autor:
Nekeithia S. Wade, Christine M. Coquery, William M. Loo, Kenneth S. K. Tung, Loren D. Erickson, Henry Hess, Janet E. Lewis, Annelise G. Bederman
Publikováno v:
Arthritis & Rheumatology. 67:773-784
Peripheral B-cell responses to foreign antigen is a tightly regulated process with multiple checkpoints that generate protective antibodies and prevent the development of autoantibodies (1). The coordinated interplay between antigen-specific B-cells
Publikováno v:
Annals of the Rheumatic Diseases
Objective Accelerated atherosclerosis is a major source of morbidity in systemic lupus erythematosus (SLE). However, the cause of SLE-accelerated atherosclerosis remains unclear. Methods CD4 + T cells from C57/Bl/6 (B6) or SLE-susceptible B6.Sle1.2.3
Autor:
John J.P. Kastelein, Sander I. van Leuven, Paul P. Tak, Yanice V. Mendez-Fernandez, Ashley J. Wilhelm, Nekeithia S. Wade, Amy S. Major, Curtis L. Gabriel, Erik S.G. Stroes
Publikováno v:
Annals of the rheumatic diseases, 71(3), 408-414. BMJ Publishing Group
RationaleRecent clinical and preclinical studies have demonstrated that systemic lupus erythematosus (SLE) is associated with an increased risk for cardiovascular disease (CVD). However, unlike in the general population, little is known regarding the
Autor:
Nekeithia S. Wade, Amy S. Major
Publikováno v:
Thrombosis and Haemostasis. 106:849-857
SummaryRheumatic autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus (SLE), are associated with antibodies to “self” antigens. Persons with autoimmune diseases, most notably SLE, are at increased risk for developing
Autor:
Roman Covarrubias, Amy S. Major, Yanice V. Mendez-Fernandez, Nekeithia S. Wade, Joseph L. Witztum, Cody J. Diehl, Sander I. van Leuven, Bonnie G. Stevenson, Nicole A. Braun
Publikováno v:
Atherosclerosis. 214:73-80
Atherosclerosis is widely accepted as an inflammatory disease involving both innate and adaptive immunity. B cells and/or antibodies have previously been shown to play a protective role against atherosclerosis. Aside from their ability to bind to ant
Autor:
Christine M, Coquery, William M, Loo, Nekeithia S, Wade, Annelise G, Bederman, Kenneth S, Tung, Janet E, Lewis, Henry, Hess, Loren D, Erickson
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 67(3)
Follicular helper T (Tfh) cells are critical for the development of protective antibodies via germinal center (GC) B cell responses; however, uncontrolled Tfh cell expansion activates autoreactive B cells to produce antibodies that cause autoimmunity
Autor:
Jason M. Kinchen, Kenneth S. K. Tung, Christine M. Coquery, Chao Jiang, Loren D. Erickson, Kelly M. Cox, William M. Loo, Nekeithia S. Wade
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102284 (2014)
PLoS ONE
PLoS ONE
Despite increased frequencies of neutrophils found in autoimmune diseases such as systemic lupus erythematosus (SLE), how they contribute to disease pathogenesis and the mechanisms that affect the accumulation of neutrophils are poorly understood. Th
Cardiovascular disease risk is increased in individuals suffering from systemic lupus erythematosus. Understanding the mechanism(s) of systemic lupus erythematosus-accelerated atherosclerosis is critical for the development of effective therapies. Ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ec90b3651c3a764a717fec35b68255
https://europepmc.org/articles/PMC2802678/
https://europepmc.org/articles/PMC2802678/