Zobrazeno 1 - 10
of 605
pro vyhledávání: '"Nejsum, P."'
Autor:
Anders Toftegaard Boysen, Bradley Whitehead, Anne Louise S. Revenfeld, Dhanu Gupta, Thor Petersen, Peter Nejsum
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Background Mesenchymal stromal cell (MSC) therapy holds great potential yet efficacy and safety concerns with cell therapy persist. The beneficial effects of MSCs are often attributed to their secretome that includes extracellular vesicles (
Externí odkaz:
https://doaj.org/article/f65f2ed2c53a4728b3f2f9b003684449
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-8 (2024)
Abstract Glioblastoma is a highly heterogeneous tumor whose pathophysiological complexities dictate both the diagnosis of disease severity as well as response to therapy. Conventional diagnostic tools and standard treatment regimens have only managed
Externí odkaz:
https://doaj.org/article/b3745fbc1efc439588313fc20e19d5f8
Autor:
Ben P. Jones, Kezia Kozel, Allen Jethro I. Alonte, Kennesa Klariz R. Llanes, Alexandra Juhász, Umer Chaudhry, Sara Roose, Peter Geldhof, Vicente Y. Belizario, Peter Nejsum, J. Russell Stothard, E. James LaCourse, Arnoud H. M. van Vliet, Vachel Gay V. Paller, Martha Betson
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background The giant roundworm Ascaris is an intestinal nematode, causing ascariasis by infecting humans and pigs worldwide. Recent estimates suggest that Ascaris infects over half a billion people, with chronic infections leading to reduced
Externí odkaz:
https://doaj.org/article/b4210f3b9f79462e8600b4f600cb0dd4
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110614- (2024)
Summary: In this study, we assessed the quality of de novo genome assemblies for three species of parasitic nematodes (Brugia malayi, Trichuris trichiura, and Ancylostoma caninum) generated using only Oxford Nanopore Technologies MinION data. Assembl
Externí odkaz:
https://doaj.org/article/c0481e7dbab541e3baf5bda2a6af6bf4
Autor:
Emil Gregersen, Jean-Claude Kresse, Jasmine Cicek Leifing Atay, Anders Toftegaard Boysen, Peter Nejsum, Marco Eijken, Rikke Nørregaard
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Renal fibrosis, characterized by excessive extracellular matrix accumulation, leads to a progressive decline of renal function and is a common endpoint of chronic kidney disease (CKD). Current treatments primarily focus on managing underlying disease
Externí odkaz:
https://doaj.org/article/8e3c52e63b684d68b09e102db319da58
Autor:
Anna Marlene Schmid, Agnieszka Razim, Magdalena Wysmołek, Daniela Kerekes, Melissa Haunstetter, Paul Kohl, Georgii Brazhnikov, Nora Geissler, Michael Thaler, Eliška Krčmářová, Martin Šindelář, Tamara Weinmayer, Jiří Hrdý, Katy Schmidt, Peter Nejsum, Bradley Whitehead, Johan Palmfeldt, Stefan Schild, Aleksandra Inić-Kanada, Ursula Wiedermann, Irma Schabussova
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background E. coli O83 (Colinfant Newborn) is a Gram-negative (G-) probiotic bacterium used in the clinic. When administered orally, it reduces allergic sensitisation but not allergic asthma. Intranasal administration offers a non-invasive a
Externí odkaz:
https://doaj.org/article/d083c2cca21546f9bff047f761f3090b
Autor:
Nathalie Acevedo, Ana Lozano, Josefina Zakzuk, Kevin Llinás-Caballero, David Brodin, Peter Nejsum, Andrew R. Williams, Luis Caraballo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAscaris lumbricoides cystatin (Al-CPI) prevents the development of allergic airway inflammation and dextran-induced colitis in mice models. It has been suggested that helminth-derived cystatins inhibit cathepsins in dendritic cells (DC), bu
Externí odkaz:
https://doaj.org/article/a9d51a70d2224ea4b19bed7ff98a9752
Autor:
Pernille Bogetofte Thomasen, Alena Salasova, Kasper Kjaer-Sorensen, Lucie Woloszczuková, Josef Lavický, Hande Login, Jeppe Tranberg-Jensen, Sergio Almeida, Sander Beel, Michaela Kavková, Per Qvist, Mads Kjolby, Peter Lund Ovesen, Stella Nolte, Benedicte Vestergaard, Andreea-Cornelia Udrea, Lene Niemann Nejsum, Moses V. Chao, Philip Van Damme, Jan Krivanek, Jeremy Dasen, Claus Oxvig, Anders Nykjaer
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113333- (2023)
Summary: Motor neuron (MN) development and nerve regeneration requires orchestrated action of a vast number of molecules. Here, we identify SorCS2 as a progranulin (PGRN) receptor that is required for MN diversification and axon outgrowth in zebrafis
Externí odkaz:
https://doaj.org/article/70f099b4a581474b967f6fa6ea663779
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Akademický článek
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