Loss of Anks6 leads to YAP deficiency and liver abnormalities.

Autor: Airik M; Division of Nephrology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA., Schüler M; Division of Nephrology and Internal Intensive Care Medicine, Charite University, Berlin, Germany.; Division of Nephrology, Boston Children's Hospital, Boston, MA, USA., McCourt B; Division of Nephrology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA., Weiss AC; Department for Molecular Biology, Hannover, Germany., Herdman N; Division of Nephrology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA., Lüdtke TH; Department for Molecular Biology, Hannover, Germany., Widmeier E; Division of Nephrology, Boston Children's Hospital, Boston, MA, USA.; Department of Medicine, Renal Division, Medical Center - University of Freiburg, Freiburg, Germany., Stolz DB; Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA, USA., Nejak-Bowen KN; Division of Experimental Pathology, Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA., Yimlamai D; Division of Gastroenterology and Nutrition, Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA., Wu YL; Department of Developmental Biology, University of Pittsburgh, Pittsburgh, PA, USA., Kispert A; Department for Molecular Biology, Hannover, Germany., Airik R; Division of Nephrology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Developmental Biology, University of Pittsburgh, Pittsburgh, PA, USA., Hildebrandt F; Division of Nephrology, Boston Children's Hospital, Boston, MA, USA.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2020 Nov 04; Vol. 29 (18), pp. 3064-3080.

Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis.

Autor: Pradhan-Sundd T; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA., Zhou L; Department of General Surgery, School of Medicine, Xi'an Jiaotong University, China., Vats R; Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA., Jiang A; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA., Molina L; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA., Singh S; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA., Poddar M; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA., Russell J; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA., Stolz DB; Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA.; Pittsburgh Liver Research Center, University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine, Pittsburgh, PA., Oertel M; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA.; Pittsburgh Liver Research Center, University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine, Pittsburgh, PA., Apte U; Department of Pharmacology, Toxicology and Therapeutics, Kansas University Medical Center, Kansas City, KS., Watkins S; Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA.; Pittsburgh Liver Research Center, University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine, Pittsburgh, PA., Ranganathan S; Pittsburgh Liver Research Center, University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine, Pittsburgh, PA.; Children's Hospital of Pittsburgh, Pittsburgh, PA., Nejak-Bowen KN; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA.; Pittsburgh Liver Research Center, University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine, Pittsburgh, PA., Sundd P; Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.; Pittsburgh Liver Research Center, University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine, Pittsburgh, PA.; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA., Monga SP; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA.; Pittsburgh Liver Research Center, University of Pittsburgh Medical Center and University of Pittsburgh School of Medicine, Pittsburgh, PA.; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2018 Jun; Vol. 67 (6), pp. 2320-2337. Date of Electronic Publication: 2018 Apr 19.

Mice with Hepatic Loss of the Desmosomal Protein γ-Catenin Are Prone to Cholestatic Injury and Chemical Carcinogenesis.

Autor: Zhou L; Department of General Surgery, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China; Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania., Pradhan-Sundd T; Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania., Poddar M; Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania., Singh S; Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania., Kikuchi A; Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania., Stolz DB; Department of Cell Biology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania., Shou W; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana., Li Z; Department of General Surgery, The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China., Nejak-Bowen KN; Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania., Monga SP; Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania; Department of Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania. Electronic address: smonga@pitt.edu.

Publikováno v: The American journal of pathology [Am J Pathol] 2015 Dec; Vol. 185 (12), pp. 3274-89. Date of Electronic Publication: 2015 Oct 17.

Complete response of Ctnnb1-mutated tumours to β-catenin suppression by locked nucleic acid antisense in a mouse hepatocarcinogenesis model.

Autor: Delgado E; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Okabe H; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Preziosi M; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Russell JO; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Alvarado TF; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Oertel M; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Nejak-Bowen KN; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Zhang Y; Enzon Pharmaceuticals, New Jersey, USA., Monga SP; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: smonga@pitt.edu.

Publikováno v: Journal of hepatology [J Hepatol] 2015 Feb; Vol. 62 (2), pp. 380-7. Date of Electronic Publication: 2014 Oct 18.

β-Catenin signaling in hepatocellular cancer: Implications in inflammation, fibrosis, and proliferation.

Autor: Lee JM; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Yang J; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Newell P; Hepatobiliary and Pancreatic Surgery Program, Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR, USA., Singh S; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Parwani A; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Friedman SL; Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA., Nejak-Bowen KN; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Monga SP; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: smonga@pitt.edu.

Publikováno v: Cancer letters [Cancer Lett] 2014 Feb 01; Vol. 343 (1), pp. 90-7. Date of Electronic Publication: 2013 Sep 23.