Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Neja Šamec"'
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e21070- (2023)
Glioblastoma is an extremely lethal cancer characterized by great heterogeneity at different molecular and cellular levels. As a result, treatment options have moved far from systemic and universal therapies toward targeted treatments and personalize
Externí odkaz:
https://doaj.org/article/0bf42d31b69045e2817de65219498c6d
Publikováno v:
Heliyon, Vol 9, Iss 5, Pp e15674- (2023)
Glioblastoma is one of the deadliest cancers, therefore novel efficient therapeutic approaches are urgently required. One of such are nanobodies, prospective nano-sized bio-drugs with advantageous characteristics. Nanobodies can target intracellular
Externí odkaz:
https://doaj.org/article/0257c9d36db14ca69b4f718bf7607863
Autor:
Šimen Ravnik, Ines Žabkar, Uršula Prosenc Zmrzljak, Ivana Jovčevska, Neja Šamec, Miha Moškon, Alja Videtič Paska
Publikováno v:
Biomedical Engineering and Computational Biology, Vol 12 (2021)
With the increasing number of molecular biology techniques, large numbers of oligonucleotides are frequently involved in individual research projects. Thus, a dedicated electronic oligonucleotide management system is expected to provide several benef
Externí odkaz:
https://doaj.org/article/82417caeba91450d8df2f6c40ed97a0b
Autor:
Alja Zottel, Ivana Jovčevska, Neja Šamec, Jernej Mlakar, Jernej Šribar, Igor Križaj, Marija Skoblar Vidmar, Radovan Komel
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Glioblastoma is a particularly common and very aggressive primary brain tumour. One of the main causes of therapy failure is the presence of glioblastoma stem cells that are resistant to chemotherapy and radiotherapy, and that have the po
Externí odkaz:
https://doaj.org/article/cc58cda6d970464094497c142708a058
Autor:
Andrej Porčnik, Metka Novak, Barbara Breznik, Bernarda Majc, Barbara Hrastar, Neja Šamec, Alja Zottel, Ivana Jovčevska, Miloš Vittori, Ana Rotter, Radovan Komel, Tamara Lah Turnšek
Publikováno v:
Molecules, Vol 26, Iss 17, p 5141 (2021)
Glioblastoma (GB), is the most common and aggressive malignant primary brain tumour in adults. Intra- and inter-tumour heterogeneity, infiltrative GB cell invasion and presence of therapy-resistant GB stem cells (GSCs) represent major obstacles to fa
Externí odkaz:
https://doaj.org/article/a9267ae6953b4ef5a6b6133183695c61
Publikováno v:
Molecules, Vol 25, Iss 3, p 490 (2020)
Owing to the advancement of technology combined with our deeper knowledge of human nature and diseases, we are able to move towards precision medicine, where patients are treated at the individual level in concordance with their genetic profiles. Lat
Externí odkaz:
https://doaj.org/article/a9ac1577c1b14c6bbbd3e1477b091f12
Autor:
Alf Giese, Victor Tkachev, Andrew Garazha, Anton Buzdin, Alexey Moisseev, Alja Zottel, Ella Kim, Marianna Zolotovskaia, Sven R. Kantelhardt, Denis Kuzmin, Bettina Sprang, Sven-Ernö Bikar, Neja Šamec, Victor Efimov, Ivana Jovčevska, Maxim Sorokin
Publikováno v:
Cancers, vol. 13, no. 16, 4117, 2021.
Cancers
Volume 13
Issue 16
Cancers, Vol 13, Iss 4117, p 4117 (2021)
Cancers
Volume 13
Issue 16
Cancers, Vol 13, Iss 4117, p 4117 (2021)
Gliomas are the most common malignant brain tumors with high mortality rates. Recently we showed that the FREM2 gene has a role in glioblastoma progression. Here we reconstructed the FREM2 molecular pathway using the human interactome model. We asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52c926eeea9276f276c3414cdda023f
https://hdl.handle.net/20.500.12556/RUL-135973
https://hdl.handle.net/20.500.12556/RUL-135973
Autor:
Barbara Hrastar, Tamara Lah Turnšek, Metka Novak, Ivana Jovčevska, Neja Šamec, Alja Zottel, Barbara Breznik, Andrej Porčnik, Radovan Komel, Miloš Vittori, Ana Rotter, Bernarda Majc
Publikováno v:
Molecules
Molecules, Vol 26, Iss 5141, p 5141 (2021)
Molecules, vol. 26, no. 17, 5141, 2021.
Volume 26
Issue 17
Molecules, Vol 26, Iss 5141, p 5141 (2021)
Molecules, vol. 26, no. 17, 5141, 2021.
Volume 26
Issue 17
Glioblastoma (GB), is the most common and aggressive malignant primary brain tumour in adults. Intra- and inter-tumour heterogeneity, infiltrative GB cell invasion and presence of therapy-resistant GB stem cells (GSCs) represent major obstacles to fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4520f673e271ab68a7c68a9b49d8783b
http://europepmc.org/articles/PMC8434287
http://europepmc.org/articles/PMC8434287
Autor:
Marianna, Zolotovskaia, Victor, Tkachev, Maxim, Sorokin, Andrew, Garazha, Ella, Kim, Sven Rainer, Kantelhardt, Sven-Ernö, Bikar, Alja, Zottel, Neja, Šamec, Denis, Kuzmin, Bettina, Sprang, Alexey, Moisseev, Alf, Giese, Victor, Efimov, Ivana, Jovčevska, Anton, Buzdin
Publikováno v:
Cancers
Simple Summary Gliomas are the most common malignant brain tumors with high mortality rates. Recently the role of the FREM2 gene has been shown in glioblastoma progression. Here we reconstructed the FREM2 molecular pathway. We assessed the biomarker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e97623204f07f1a1da94aeca6481b8a6
https://pubmed.ncbi.nlm.nih.gov/34439271
https://pubmed.ncbi.nlm.nih.gov/34439271
Autor:
Maxim, Sorokin, Mikhail, Raevskiy, Alja, Zottel, Neja, Šamec, Marija, Skoblar Vidmar, Alenka, Matjašič, Andrej, Zupan, Jernej, Mlakar, Maria, Suntsova, Denis V, Kuzmin, Anton, Buzdin, Ivana, Jovčevska
Publikováno v:
Cancers
Simple Summary Most glioblastoma patients succumb to the disease within 12 to 18 months, and only 9% are alive 2 years after diagnosis. Even with extensive research, the life expectancy of glioblastoma patients has not changed in decades. We aimed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0580209bab34c8f7a561b082ae719c49
https://pubmed.ncbi.nlm.nih.gov/34298634
https://pubmed.ncbi.nlm.nih.gov/34298634