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pro vyhledávání: '"Neill H. Stacey"'
Autor:
Ludwig Müller, Neill H. Stacey
Publikováno v:
Regulatory Toxicology ISBN: 9783642353734
Regulatory Toxicology ISBN: 9783642362064
Regulatory Toxicology ISBN: 9783642362064
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e45d1d6e7c82bd04f44699d4225142
https://doi.org/10.1007/978-3-030-57499-4_63
https://doi.org/10.1007/978-3-030-57499-4_63
Publikováno v:
Australian Prescriber. 44:186
Autor:
Neill H. Stacey, Masoud Neghab
Publikováno v:
Toxicology. 120:1-10
Occupational exposure to a mixture of two widely used aromatic hydrocarbon solvents, xylene and toluene, has been associated with a significant rise in the concentrations of serum bile acids (SBA). We have recently shown that toluene interferes with
Publikováno v:
Biomarkers. 2:3-16
DNA adducts resulting from carcinogenic chemicals are becoming more frequently used as a powerful biomarker to determine the extent of exposure. The available techniques for determination of bulky DNA adducts can be classified into four major groups,
Publikováno v:
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2(2)
The potential carcinogenic effects of exposure to diesel engine emissions (DEE) are of growing concern. Due to the use of diesel equipment in underground mines, DNA adducts in peripheral blood mononuclear cells have been measured using the (32)P-post
Serum bile acids as a sensitive biological marker for evaluating hepatic effects of organic solvents
Autor:
Neill H. Stacey, Masoud Neghab
Publikováno v:
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 5(2)
Serum bile acids (SBAs) are suggested as a potentially sensitive and specific indicator of liver function which, accordingly, could provide an early indication of hepatobiliary dysfunction. This offers advantages over more traditional parameters of l
Publikováno v:
Toxicology in Vitro. 10:665-674
It has previously been shown that trichloroethylene (TRI) and 1,1,2-trichloro-1,2,2-tri-fluoroethane (FC 113) interfere with the transport of bile acids by isolated human and rat hepatocytes in a dose-dependent and reversible manner. This finding may
Autor:
Neill H. Stacey, S.-X. Qu
Publikováno v:
Toxicology in Vitro. 10:685-692
Polycyclic aromatic hydrocarbons (PAHs) and nitro-PAHs have been identified widely in occupational and environmental pollution, such as diesel engine emissions and other combustion products. In most cases, hepatic biotransformation is involved in con
Publikováno v:
International Archives of Occupational and Environmental Health. 69:21-26
The effects of exposure to solvents on serum bile acids were investigated by comparing a group of apprentice vehicle spray painters (exposed group) with one of apprentice electricians. Apprentice spray painters from the study were subdivided into hig
Autor:
Neill H. Stacey, Samy A. Azer
Publikováno v:
Journal of Gastroenterology and Hepatology. 11:396-407
Hepatic sinusoidal uptake of bile acids is mediated by defined carrier proteins against unfavourable concentration and electrical gradients. Putative carrier proteins have been identified using bile acid photoaffinity labels and more recently using i