Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Neil W, Kooy"'
Autor:
Neil W. Kooy, Stephen J. Lewis, James N. Bates, Tom P. Robertson, Kevin Sandock, Azizul Hoque
Publikováno v:
Vascular Pharmacology. 46:24-34
Objective The aim of this study was to provide evidence that peroxynitrite may differentially affect the function of arginine vasopressin (AVP) V1a receptors and α1-adrenoceptors in vascular smooth muscle of the rat Methods The vasoconstrictor respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9336cb8e3c6d606258869a9cb4d1afd1
https://doi.org/10.1016/j.vph.2006.06.004
https://doi.org/10.1016/j.vph.2006.06.004
Publikováno v:
British Journal of Pharmacology. 148:7-15
1 There is direct chemical evidence that L-β,β-dimethylcysteine (L-penicillamine (L-PEN)) is a scavenger of peroxynitrite. The aim of this study was to determine whether L-PEN attenuates the haemodynamic responses elicited by peroxynitrite in pento
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4161c0f18fcf6c4502d157225937f68e
https://doi.org/10.1038/sj.bjp.0706692
https://doi.org/10.1038/sj.bjp.0706692
Publikováno v:
Digestive Diseases and Sciences. 48:2353-2359
Intestinal mucosa serves as an important barrier that may be disrupted by inflammation. A complex system of cellular and humoral factors, including epidermal growth factor (EGF), maintains the integrity of this barrier. We hypothesized that peroxynit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2ba718b8e6ac84f37f1ed84ec9f8db
https://doi.org/10.1023/b:ddas.0000007874.20403.1d
https://doi.org/10.1023/b:ddas.0000007874.20403.1d
Autor:
Neil W Kooy, Derek S. Wheeler
Publikováno v:
Critical Care Clinics. 19:365-391
It is generally well accepted that one third of patients with viral myocarditis experience a complete recovery of normal cardiac function, one third improve clinically but show residual cardiac dysfunction, and one third experience chronic heart fail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d6bb6dae5c9143eb94a665e1f75c481
https://doi.org/10.1016/s0749-0704(03)00006-x
https://doi.org/10.1016/s0749-0704(03)00006-x
Publikováno v:
Experimental Lung Research. 28:609-622
High concentrations of oxygen (hyperoxia) are known to cause cellular injury and death. The heat shock response is a highly conserved cellular defense mechanism that protects cells against various environmental stressors, including hyperoxia. Herein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3cecbf7120907b6cf10cc086aacfd9
https://doi.org/10.1080/01902140260426724
https://doi.org/10.1080/01902140260426724
Publikováno v:
Digestive Diseases and Sciences. 46:30-37
Nitric oxide (NO·) is a mediator of esophageal motility. Esophageal dysmotility accompanies esophagitis. During inflammation, superoxide and NO· form peroxynitrite (ONOO-), a reactive molecule that alters cellular function. We tested the hypotheses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::578a1e747e900932ac644b64f3a168e5
https://doi.org/10.1023/a:1005596328395
https://doi.org/10.1023/a:1005596328395
Publikováno v:
European Journal of Pharmacology. 401:403-412
In vitro studies have provided evidence that Cl(-) ion currents are important for activation of vascular smooth muscle contraction. The stilbene, 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS), disrupts Cl(-) metabolism by blocking Cl(-) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d8c699f09b6d07005318b78395abfc
https://doi.org/10.1016/s0014-2999(00)00471-4
https://doi.org/10.1016/s0014-2999(00)00471-4
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 275:H501-H508
Peroxynitrite, formed endogenously by the near diffusion-limited reaction of nitric oxide with superoxide anion, induces vascular relaxation. This effect is subject to rapid tachyphylaxis, suggesting that peroxynitrite may alter subsequent vasorelaxa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7464d5a4fe7ae8194ffd0c5cdea28209
https://doi.org/10.1152/ajpheart.1998.275.2.h501
https://doi.org/10.1152/ajpheart.1998.275.2.h501
Autor:
N Lee, Zuhair K. Ballas, Myrl Holida, A. L. Gilman, S Rumelhart, Frederick D. Goldman, Neil W. Kooy, D. L. Atkins
Publikováno v:
Bone Marrow Transplantation. 21:85-88
An infant who received haploidentical BM for severe combined immunodeficiency (SCID) developed acute, reversible complete heart block in association with an exacerbation of GVHD. Respiratory distress and myocardial dysfunction were also seen with thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51c8e679a20bbe80a658a878445c3e8
https://doi.org/10.1038/sj.bmt.1701038
https://doi.org/10.1038/sj.bmt.1701038
Autor:
Stephen J. Lewis, Neil W. Kooy, Yao Z. Ye, David R. Kelly, James A. Royall, Joseph S. Beckman
Publikováno v:
Critical Care Medicine. 25:812-819
Objectives Production of nitric oxide via the cytokine-mediated activation of myocardial inducible nitric oxide synthase decreases myocardial contractility. Whether myocardial dysfunction is mediated directly by nitric oxide or indirectly through the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86928426a13bdb336691d4bee9301a45
https://doi.org/10.1097/00003246-199705000-00017
https://doi.org/10.1097/00003246-199705000-00017