Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Neil Stephen Renninger"'
Publikováno v:
Biotechnology Progress. 24:1026-1032
Artemisinin-based combination therapies (ACTs) are currently unaffordable for many of the people who need them most. A major cost component of ACTs is the plant-derived artemisinin. A fermentation process for a precursor to artemisinin might provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc6802274d0077559c2cccc344500a2
https://doi.org/10.1002/btpr.27
https://doi.org/10.1002/btpr.27
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 77:198-202
Despite considerable efforts by multiple governmental and nongovernmental organizations to increase access to artemisinin-based combination therapies (ACTs), these life-saving antimalarial drugs remain largely unaffordable to the most vulnerable popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb88a4210f8ee731ad6c6c5600efaaad
https://doi.org/10.4269/ajtmh.2007.77.198
https://doi.org/10.4269/ajtmh.2007.77.198
Publikováno v:
Applied and Environmental Microbiology. 70:7404-7412
The polyphosphate kinase gene from Pseudomonas aeruginosa was overexpressed in its native host, resulting in the accumulation of 100 times the polyphosphate seen with control strains. Degradation of this polyphosphate was induced by carbon starvation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7298b8f77e91c8787e3744d0736244fe
https://doi.org/10.1128/aem.70.12.7404-7412.2004
https://doi.org/10.1128/aem.70.12.7404-7412.2004
Autor:
Douglas S. Clark, Jay D. Keasling, Katherine D. McMahon, Neil Stephen Renninger, Heino Nitsche, Roger Knopp
Publikováno v:
Biodegradation. 12:401-410
Heavy metal and radionuclide contamination presents a significant environmental problem worldwide. Precipitation of heavy metals on membranes of cells that secrete phosphate has been shown to be an effective method of reducing the volume of these was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d26affdda6bdff4b7eb11e7911daa103
https://doi.org/10.1023/a:1015018104682
https://doi.org/10.1023/a:1015018104682
Autor:
David J. Melis, Michael D. Leavell, Chris J. Paddon, Diana Eng, Tizita Horning, Jack D. Newman, Neil Stephen Renninger, Jay D. Keasling, Jacob R. Lenihan, Patrick J. Westfall, Rika Regentin, Derek McPhee, Andrew Owens, Frank X. Woolard, Kirsten R. Benjamin, Scott Fickes, Don Diola, Douglas J. Pitera, Hiroko Tsuruta
Publikováno v:
Proceedings of the National Academy of Sciences. 109
Malaria, caused by Plasmodium sp , results in almost one million deaths and over 200 million new infections annually. The World Health Organization has recommended that artemisinin-based combination therapies be used for treatment of malaria. Artemis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3795724f56b96b08013cbfd35bfacf3f
https://doi.org/10.1073/pnas.1110740109
https://doi.org/10.1073/pnas.1110740109
Autor:
Denise Ann Ockey, Neil Stephen Renninger, Yasuo Yoshikuni, Derek McPhee, Frank X. Woolard, David Baker, Michelle C. Y. Chang, Jay D. Keasling, Karl Fisher, Jeffrey A. Dietrich
Publikováno v:
ACS chemical biology. 4(4)
Production of fine chemicals from heterologous pathways in microbial hosts is frequently hindered by insufficient knowledge of the native metabolic pathway and its cognate enzymes; often the pathway is unresolved, and the enzymes lack detailed charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac6adc50d92b84ecdad175af6cb228a
https://pubmed.ncbi.nlm.nih.gov/19271725
https://pubmed.ncbi.nlm.nih.gov/19271725
Autor:
Diana Eng, Tizita Horning, Christopher J. Paddon, Larry Cameron Anthony, Jacob R. Lenihan, Jack D. Newman, Jay D. Keasling, Neil Stephen Renninger, Rika Regentin, Hiroko Tsuruta
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4489 (2009)
PloS one, vol 4, iss 2
PLoS ONE
PloS one, vol 4, iss 2
PLoS ONE
BackgroundArtemisinin derivatives are the key active ingredients in Artemisinin combination therapies (ACTs), the most effective therapies available for treatment of malaria. Because the raw material is extracted from plants with long growing seasons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9178d7938d7060ee3a072a5964abf67f
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19221601/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19221601/?tool=EBI
Autor:
Heino Nitsche, Roger Knopp, Neil Stephen Renninger, Jay D. Keasling, Lewis A. Wray, Petra J. Panak
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 9(12)
We have investigated the interactions of UVI with two bacterial phosphate-containing species: Gram-positive Bacillus sphaericus and Gram-negative Pseudomonas aeruginosa. The Gram-positive B. sphaericus was investigated by using Raman spectroscopy and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c650e7077ee00e20baecb600407cc6f7
https://pubmed.ncbi.nlm.nih.gov/12866546
https://pubmed.ncbi.nlm.nih.gov/12866546