Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Neil S Shachter"'
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 7, Pp 1476-1487 (2007)
Apolipoprotein A-V (apoA-V) and apoC-III are exchangeable constituents of VLDL and HDL. ApoA-V counteracts the effect of apoC-III on triglyceride (TG) metabolism with poorly defined mechanisms. To better understand the effects of apoA-V on TG and cho
Externí odkaz:
https://doaj.org/article/83be7f352c644be9a6111dcd96765dff
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 12, Pp 2368-2376 (2004)
Presenilin-1 (PS1) is an important determinant of the γ-secretase activity necessary for the generation of β-amyloid (Aβ), likely the central pathogenic molecule in Alzheimer's disease. Most presenilin is rapidly degraded, and determinants of the
Externí odkaz:
https://doaj.org/article/75a4e3ab9dac4c679a41f188f4d90ae0
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 12, Pp 2136-2145 (2002)
Apolipoprotein C-I (apoC22222222246) has been proposed to act primarily via interference with apoE-mediated lipoprotein uptake. To define actions of apoC-I that are independent of apoE, we crossed a moderately overexpressing human apoC-I transgenic,
Externí odkaz:
https://doaj.org/article/c7369495f16c479d8cc444a658ae8c0d
Autor:
Caroline Petit-Turcotte, Sheldon M. Stohl, Uwe Beffert, Jeffrey S. Cohn, Nicole Aumont, Michel Tremblay, Doris Dea, Lin Yang, Judes Poirier, Neil S. Shachter
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 6, Pp 953-963 (2001)
The H2 allele of apolipoprotein (apo) C-I is associated with Alzheimer's disease (AD). However, this association is potentially confounded by the linkage disequilibrium of H2 with the ϵ2 and ϵ4 alleles of apoE and of H1 with the ϵ3 allele. To esta
Externí odkaz:
https://doaj.org/article/fefdbe1e0ceb423184b4146883a63b91
Autor:
Yan Xu, Lars Berglund, Rajasekhar Ramakrishnan, Richard Mayeux, Colleen Ngai, Steven Holleran, Benjamin Tycko, Todd Leff, Neil S. Shachter
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 1, Pp 50-58 (1999)
Apolipoprotein (apo) C-I is a constituent of triglyceride-rich lipoproteins (TGRL) that interferes with their hepatic clearance. Functional polymorphism in the apoC-I gene has not been established. We determined that an Hpa I site variably present at
Externí odkaz:
https://doaj.org/article/098658dbac51490886c38ba0eee28060
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 7, Pp 1472-1478 (2009)
Apolipoproteins (apo) E and C-I are components of triglyceride (TG)-rich lipoproteins and impact their metabolism. Functional polymorphisms have been established in apoE but not in apoC-I. We studied the relationship between apoE and apoC-I gene poly
Autor:
Neil S. Shachter, Jeff S. Volek, John H. Contois, Maria Luz Fernandez, Richard J. Wood, Yanzhu Liu
Publikováno v:
The Journal of Nutrition. 136:384-389
To determine the effects of carbohydrate restriction (CR) with and without soluble fiber on lipoprotein metabolism, 29 men participated in a 12-wk weight loss intervention. Subjects were matched by age and BMI and randomly assigned to consume 3 g/d o
Autor:
Tosca L. Zern, Yanzhu Liu, Richard J. Wood, Maria Luz Fernandez, Christine M Greene, Neil S. Shachter, Kristy L. West, Dimple Aggarwal
Publikováno v:
The Journal of Nutrition. 135:1911-1917
To evaluate the effects of grape polyphenols on plasma lipids, inflammatory cytokines, and oxidative stress, 24 pre- and 20 postmenopausal women were randomly assigned to consume 36 g of a lyophilized grape powder (LGP) or a placebo for 4 wk. The LGP
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 12, Pp 2368-2376 (2004)
Presenilin-1 (PS1) is an important determinant of the gamma-secretase activity necessary for the generation of beta-amyloid (Abeta), likely the central pathogenic molecule in Alzheimer's disease. Most presenilin is rapidly degraded, and determinants
Autor:
Neil S. Shachter, Sung I. Koo, Ingrid E. Lofgren, Kristy L. West, Kristin L. Herron, Tosca L. Zern, Maria Luz Fernandez, Madhu Patalay
Publikováno v:
The Journal of Nutrition. 134:1071-1076
Waist circumference (WC) has been postulated to have stronger associations with biomarkers of coronary heart disease (CHD) than BMI. In this study, we measured the level of activity by determining steps walked per day and select biomarkers for CHD ri