Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Neil S Millar"'
Autor:
Charles L C Smelt, Victoria R Sanders, Alin M Puinean, Stuart J Lansdell, Jim Goodchild, Neil S Millar
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254251 (2021)
Pentameric ligand-gated ion channels (pLGICs) activated by the inhibitory neurotransmitter γ-aminobutyric acid (GABA) are expressed widely in both vertebrate and invertebrate species. One of the best characterised insect GABA-gated chloride channels
Externí odkaz:
https://doaj.org/article/408c4c3db8234580a3db059b44035dff
Autor:
Anna Chatzidaki, Antoine Fouillet, Jingling Li, Jeffrey Dage, Neil S Millar, Emanuele Sher, Daniel Ursu
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125116 (2015)
Neurons derived from human induced pluripotent stem cells (iPSCs) represent a potentially valuable tool for the characterisation of neuronal receptors and ion channels. Previous studies on iPSC-derived neuronal cells have reported the functional char
Externí odkaz:
https://doaj.org/article/48145ceffbc640209ab8c82d6a69731d
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55047 (2013)
Subtype-selective ligands are important tools for the pharmacological characterisation of neurotransmitter receptors. This is particularly the case for nicotinic acetylcholine receptors (nAChRs), given the heterogeneity of their subunit composition.
Externí odkaz:
https://doaj.org/article/8283b8096ae04ea595fff848074f10bf
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32073 (2012)
We have examined the effect of temperature on the electrophysiological properties of three neuronal nicotinic acetylcholine receptor (NACHR) subtypes: the rapidly desensitizing homomeric α7 nAChR, the more slowly desensitizing heteromeric α4β2 nAC
Externí odkaz:
https://doaj.org/article/7c849824704a470d9091a92a44e24476
Autor:
Alin M Puinean, Stephen P Foster, Linda Oliphant, Ian Denholm, Linda M Field, Neil S Millar, Martin S Williamson, Chris Bass
Publikováno v:
PLoS Genetics, Vol 6, Iss 6, p e1000999 (2010)
The aphid Myzus persicae is a globally significant crop pest that has evolved high levels of resistance to almost all classes of insecticide. To date, the neonicotinoids, an economically important class of insecticides that target nicotinic acetylcho
Externí odkaz:
https://doaj.org/article/305f332a0eae414b800ed07126188be8
Autor:
Victoria R. Sanders, Neil S. Millar
Publikováno v:
Pharmacological Research, Vol 191, Iss , Pp 106759- (2023)
Considerable progress has been made in recent years towards the identification and characterisation of novel subtype-selective modulators of nicotinic acetylcholine receptors (nAChRs). In particular, this has focussed on modulators of α7 nAChRs, a n
Externí odkaz:
https://doaj.org/article/318ad66499f947909440536d9ead5152
Publikováno v:
ACS Bio & Med Chem Au. 3:147-157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993c0705e8c391e9f4766a7b6ea9dd9b
https://doi.org/10.1021/acsbiomedchemau.2c00057
https://doi.org/10.1021/acsbiomedchemau.2c00057
Publikováno v:
ACS chemical neuroscience. 13(12)
Quinolone antibiotics disrupt bacterial DNA synthesis by interacting with DNA gyrase and topoisomerase IV. However, in addition, they have been shown to act as inhibitors of pentameric ligand-gated ion channels such as GABA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f35feb4926c9876578b7a98c5e775d
https://pubmed.ncbi.nlm.nih.gov/35657695
https://pubmed.ncbi.nlm.nih.gov/35657695
Autor:
Neil S Millar
Publikováno v:
BMJ. :p16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ace1db1903415d6c654318573135c79
https://doi.org/10.1136/bmj.p16
https://doi.org/10.1136/bmj.p16