Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Neil S Jensen"'
Autor:
Jonathan M. Oyler, Robert A. Moyer, Daniel Angelini, Neil S Jensen, Harry Salem, Kristen L. Willis, Charles Hong, Russell M. Dorsey
Publikováno v:
Inhalation Toxicology. 25:37-62
Chemical warfare agents (CWAs) as well as biological toxins present a significant inhalation injury risk to both deployed warfighters and civilian targets of terrorist attacks. Inhalation of many CWAs and biological toxins can induce severe pulmonary
Autor:
Oksana Lockridge, Kalpana Parikh, Neil S. Jensen, Veeraswamy Manne, Ellen G. Duysen, Nageswararao Chilukuri, Benjamin Snow
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 337:92-101
Gene delivery using an adenoviral system has been effective in introducing therapeutic proteins in vitro and in vivo. This study tested the feasibility of using adenovirus to deliver clinically relevant amounts of butyrylcholinesterase (BChE), a prov
Autor:
Qiahong Liu, Mark A. Doll, David F. Barker, Yan Li, David W. Hein, Robert C.G. Martin, Neil S. Jensen
Publikováno v:
DNA and Cell Biology. 28:3-7
Mitochondrial manganese superoxide dismutase (MnSOD), encoded by the SOD2 gene, represents a major cellular defense against environmental carcinogens that cause oxidative stress. Two single-nucleotide polymorphisms −9 T>C (V16A in the MnSOD mitocho
Publikováno v:
Chemico-Biological Interactions. 165:165-174
Halobenzenes are ubiquitous environmental contaminants, which are hepatotoxic in both rodents and humans. The molecular mechanism of halobenzene hepatotoxicity was investigated using Quantitative structure-activity relationships (QSAR) and accelerate
Autor:
Todd D. Porter, Guy Russo, Paul Silber, Peter J. Wedlund, Li Li, Barbara J. Ring, John B. Heim, John A. Tine, Run-Mei Pan, Neil S. Jensen
Publikováno v:
Drug Metabolism and Disposition. 34:1411-1416
Genotype/phenotype analysis with human hepatocytes has identified a new inactive CYP2D6 allele, CYP2D6*56. Cryopreserved human hepatocytes from 51 livers were evaluated for CYP2D6 activity with dextromethorphan as the probe substrate. Hepatocyte lots
Publikováno v:
Applied and Environmental Microbiology. 65:5028-5034
Brachyspira ( Serpulina ) hyodysenteriae , the etiologic agent of swine dysentery, uses the enzyme NADH oxidase to consume oxygen. To investigate possible roles for NADH oxidase in the growth and virulence of this anaerobic spirochete, mutant strains
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 11:379-382
1. Akita GY, Glenn J, Castro AE, Osburn BI: 1993, Detection of bluetongue virus in clinical samples by polymerase chain reaction. J Vet Diagn Invest 5:154–158. 2. Aradaib IE, Akita GY, Osburn BI: 1994, Detection of epizootic hemorrhagic disease vir
Publikováno v:
Journal of Bacteriology. 179:323-329
Serpulina hyodysenteriae B204 cells treated with mitomycin (20 microg of mitomycin/ml of culture broth) lysed and released bacteriophages. Bacteriophage particles, precipitated by using polyethylene glycol and purified by CsC1 density gradient ultrac
Publikováno v:
FEMS Microbiology Letters. 142:209-214
The phenotypic characteristics of three Serpulina pilosicoli strains isolated from humans with diarrhoea (WesB, Kar, Hrm7) and two porcine S. pilosicoli strains isolated from pigs with intestinal spirochaetosis (1648, 3295), were compared with the ty
Autor:
Neil S. Jensen, Thad B. Stanton, David J. Hampson, A.J. McLaren, Brace J. Paster, Darren J. Trott, Jae I. Lee
Publikováno v:
FEMS Microbiology Letters. 136:181-186
Multilocus enzyme electrophoresis (MEE) analysis and comparisons of nearly complete 16S rRNA gene sequences (1416 nucleotide positions) were used to evaluate phylogenetic relationships among Serpulina hyodysenteriae strain B78(T), S. innocens strain