Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Neil Rollins"'
Autor:
Lawrence R. Dick, Hua Liao, Neil Rollins, Xiaofeng Yang, William D. Mallender, Qing Xu, James E. Brownell, James M. Gavin, Jingyang Chen, Alexandra E. Gould, Huay-Keng Loke, Jingya Ma, Trupti Lingaraj, Benjamin S. Amidon
Publikováno v:
Journal of Biological Chemistry. 287:15512-15522
Uba6 is a homolog of the ubiquitin-activating enzyme, Uba1, and activates two ubiquitin-like proteins (UBLs), ubiquitin and FAT10. In this study, biochemical and biophysical experiments were performed to understand the mechanisms of how Uba6 recogniz
Autor:
James E. Brownell, Erik Koenig, Neil Rollins, Olga Tayber, Patrick J. LeRoy, Ping Li, Hugues Bernard, Jonathan Mandelbaum, Janice Y Lee, Pooja Shah, Doug Bowman, Natalie Roy D’Amore
Publikováno v:
Autophagy.
Autophagy is a major cellular process for bulk degradation of proteins and organelles in order to maintain metabolic homeostasis, and it represents an emerging target area for cancer. Initially proposed to be a cancer-restricting process for tumor in
Absolute quantification of E1, ubiquitin-like proteins and Nedd8-MLN4924 adduct by mass spectrometry
Autor:
Teresa A. Soucy, Michael P. Thomas, Xiaofeng Yang, Hua Liao, Qing Xu, Huay-Keng Loke, Ping Li, Neil Rollins, William D. Mallender, Fengying Zhu, Jingya Ma, Lawrence R. Dick, James J. Minissale, James E. Brownell
Publikováno v:
Cell biochemistry and biophysics. 67(1)
Ubiquitin (Ub) and ubiquitin-like (Ubl) proteins regulate a variety of important cellular processes by forming covalent conjugates with target proteins or lipids. Ubl conjugation is catalyzed by a cascade of proteins including activating enzymes (E1)