Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Neil McPhail"'
Autor:
Gerhardt Attard, Laura Murphy, Noel W Clarke, Ashwin Sachdeva, Craig Jones, Alex Hoyle, William Cross, Robert J Jones, Christopher C Parker, Silke Gillessen, Adrian Cook, Chris Brawley, Clare Gilson, Hannah Rush, Hoda Abdel-Aty, Claire L Amos, Claire Murphy, Simon Chowdhury, Zafar Malik, J Martin Russell, Nazia Parkar, Cheryl Pugh, Carlos Diaz-Montana, Carmel Pezaro, Warren Grant, Helen Saxby, Ian Pedley, Joe M O'Sullivan, Alison Birtle, Joanna Gale, Narayanan Srihari, Carys Thomas, Jacob Tanguay, John Wagstaff, Prantik Das, Emma Gray, Mymoona Alzouebi, Omi Parikh, Angus Robinson, Amir H Montazeri, James Wylie, Anjali Zarkar, Richard Cathomas, Michael D Brown, Yatin Jain, David P Dearnaley, Malcolm D Mason, Duncan Gilbert, Ruth E Langley, Robin Millman, David Matheson, Matthew R Sydes, Louise C Brown, Mahesh K B Parmar, Nicholas D James, Elin Jones, Katherine Hyde, Hilary Glen, Sarah Needleman, Ursula McGovern, Denise Sheehan, Sangeeta Paisey, Richard Shaffer, Mark Beresford, Emilio Porfiri, David Fackrell, Ling Lee, Thiagarajan Sreenivasan, Sue Brock, Simon Brown, Amit Bahl, Mike Smith-Howell, Cathryn Woodward, Mau-Don Phan, Danish Mazhar, Krishna Narahari, Fiona Douglas, Anil Kumar, Abdel Hamid, Azman Ibrahim, Dakshinamoorthy Muthukumar, Matthew Simms, Jane Worlding, Anna Tran, Mohammed Kagzi, Virgil Sivoglo, Benjamin Masters, Pek Keng-Koh, Caroline Manetta, Duncan McLaren, Nishi Gupta, Stergios Boussios, Henry Taylor, John Graham, Carla Perna, Lucinda Melcher, Ami Sabharwal, Uschi Hofmann, Robert Dealey, Neil McPhail, Robert Brierly, Lisa Capaldi, Norma Sidek, Peter Whelan, Peter Robson, Alison Falconer, Sarah Rudman, Sindu Vivekanandan, Vinod Mullessey, Maria Vilarino-Varela, Vincent Khoo, Karen Tipples, Mehran Afshar, Patryk Brulinski, Vijay Sangar, Clive Peedell, Ashraf Azzabi, Peter Hoskin, Viwod Mullassery, Santhanam Sundar, Yakhub Khan, Ruth Conroy, Andrew Protheroe, Judith Carser, Paul Rogers, Kathryn Tarver, Stephanie Gibbs, Mohammad Muneeb Khan, Mohan Hingorani, Simon Crabb, Manal Alameddine, Neeraj Bhalla, Robert Hughes, John Logue, Darren Leaning, Salil Vengalil, Daniel Ford, Georgina Walker, Ahmed Shaheen, Omar Khan, Andrew Chan, Imtiaz Ahmed, Serena Hilman, Ian Sayers, Ashok Nikapota, David Bloomfield, Tim Porter, Joji Joseph, Cyrill Rentsch, Ricardo Pereira Mestre, Enrico Roggero, Jörg Beyer, Markus Borner, Raeto Strebel, Dominik Berthold, Daniel Engeler, Hubert John, Razvan Popescu, Donat Durr
Publikováno v:
STAMPEDE investigators, Attard, G, Murphy, L, Clarke, N W, Sachdeva, A, Jones, C, Hoyle, A, Cross, W, Jones, R J, Parker, C C, Gillessen, S, Cook, A, Brawley, C, Gilson, C, Rush, H, Abdel-Aty, H, Amos, C L, Murphy, C, Chowdhury, S, Malik, Z, Russell, J M, Parkar, N, Pugh, C, Diaz-Montana, C, Pezaro, C, Grant, W, Saxby, H, Pedley, I, O'Sullivan, J M, Birtle, A, Gale, J, Srihari, N, Thomas, C, Tanguay, J, Wagstaff, J, Das, P, Gray, E, Alzouebi, M, Parikh, O, Robinson, A, Montazeri, A H, Wylie, J, Zarkar, A, Cathomas, R, Brown, M D, Jain, Y, Dearnaley, D P, Mason, M D, Gilbert, D, Langley, R E & Millman, R 2023, ' Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol ', Lancet Oncology, vol. 24, no. 5, pp. 443-456 . https://doi.org/10.1016/S1470-2045(23)00148-1
Attard, G, Murphy, L, Clarke, N W, Sachdeva, A, Jones, C, Hoyle, A, Cross, W, Jones, R J, Parker, C C, Gillessen, S, Cook, A, Brawley, C, Gilson, C, Rush, H, Abdel-Aty, H, Amos, C L, Murphy, C, Chowdhury, S, Malik, Z, Russell, J M, Parkar, N, Pugh, C, Diaz-Montana, C, Pezaro, C, Grant, W, Saxby, H, Pedley, I, O'Sullivan, J M, Birtle, A, Gale, J, Srihari, N, Thomas, C, Tanguay, J, Wagstaff, J, Das, P, Gray, E, Alzouebi, M, Parikh, O, Robinson, A, Montazeri, A H, Wylie, J, Zarkar, A, Cathomas, R, Brown, M D, Jain, Y, Dearnaley, D P, Mason, M D, Gilbert, D, Langley, R E & Millman, R 2023, ' Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy : final results from two randomised phase 3 trials of the STAMPEDE platform protocol ', The Lancet. Oncology, vol. 24, no. 5, pp. 443-456 . https://doi.org/10.1016/S1470-2045(23)00148-1
Attard, G, Murphy, L, Clarke, N W, Sachdeva, A, Jones, C, Hoyle, A, Cross, W, Jones, R J, Parker, C C, Gillessen, S, Cook, A, Brawley, C, Gilson, C, Rush, H, Abdel-Aty, H, Amos, C L, Murphy, C, Chowdhury, S, Malik, Z, Russell, J M, Parkar, N, Pugh, C, Diaz-Montana, C, Pezaro, C, Grant, W, Saxby, H, Pedley, I, O'Sullivan, J M, Birtle, A, Gale, J, Srihari, N, Thomas, C, Tanguay, J, Wagstaff, J, Das, P, Gray, E, Alzouebi, M, Parikh, O, Robinson, A, Montazeri, A H, Wylie, J, Zarkar, A, Cathomas, R, Brown, M D, Jain, Y, Dearnaley, D P, Mason, M D, Gilbert, D, Langley, R E & Millman, R 2023, ' Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy : final results from two randomised phase 3 trials of the STAMPEDE platform protocol ', The Lancet. Oncology, vol. 24, no. 5, pp. 443-456 . https://doi.org/10.1016/S1470-2045(23)00148-1
Background: Abiraterone acetate plus prednisolone (herein referred to as abiraterone) or enzalutamide added at the start of androgen deprivation therapy improves outcomes for patients with metastatic prostate cancer. Here, we aimed to evaluate long-t
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
SV loads in non-BRCA1/2 HR genes per sample by SV type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450cc60ad42d0ec76263ecb09722922f
https://doi.org/10.1158/1078-0432.22481309.v1
https://doi.org/10.1158/1078-0432.22481309.v1
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
SNVs in non-BRCA1/2 HR genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54cf8cb030ddb00004f07efa0c47311e
https://doi.org/10.1158/1078-0432.22481312.v1
https://doi.org/10.1158/1078-0432.22481312.v1
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
SVs at BRCA1/2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38554578554512bab49cac4618f6c237
https://doi.org/10.1158/1078-0432.22481321.v1
https://doi.org/10.1158/1078-0432.22481321.v1
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
Genes in KEGG HR pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfb9d43085118d213d1391cfb7e97ca
https://doi.org/10.1158/1078-0432.22481315
https://doi.org/10.1158/1078-0432.22481315
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
Supplementary tables 3a and 3b. Germline and somatic SNVs/indels at BRCA1/2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef4d7c0f6e80f6af82a9259660ce080
https://doi.org/10.1158/1078-0432.22481306.v1
https://doi.org/10.1158/1078-0432.22481306.v1
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
Differentially expressed genes in HR deficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5faed9345366149f5c7c1dc3fd4e8654
https://doi.org/10.1158/1078-0432.22481318
https://doi.org/10.1158/1078-0432.22481318
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
Number of samples with BRCA1/2 SVs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274dd2042fb42142f0d05e0fc4304c41
https://doi.org/10.1158/1078-0432.22481324
https://doi.org/10.1158/1078-0432.22481324
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
Purpose:The abundance and effects of structural variation at BRCA1/2 in tumors are not well understood. In particular, the impact of these events on homologous recombination repair deficiency (HRD) has yet to be demonstrated.Experimental Design:Explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429aee5bcef4db8eebfa46fee92e5bee
https://doi.org/10.1158/1078-0432.c.6530660.v1
https://doi.org/10.1158/1078-0432.c.6530660.v1
Autor:
Colin A. Semple, Charlie Gourley, Patricia Roxburgh, Andrew V. Biankin, Iain A. McNeish, J. Carl Barrett, Ruth March, Brian Dougherty, Athena Matakidou, Lynn McMahon, Darren Ennis, Brian McDade, Fiona Nussey, Melanie Mackean, Rosalind Glasspool, Suzanne Dowson, Nadeem Siddiqui, Neil McPhail, Trevor McGoldrick, Mairi Lennie, Michelle Ferguson, Ian Croy, Clare Bartos, Tzyvia Rye, C. Simon Herrington, Robert L. Hollis, Graeme R. Grimes, Michael Churchman, Alison Meynert, Ailith Ewing
Supplementary methods and supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c68503278e022aa60be8b0b03fbf981
https://doi.org/10.1158/1078-0432.22481327.v1
https://doi.org/10.1158/1078-0432.22481327.v1