Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Neil Mazumdar"'
Autor:
Pingzhu Zhou, Yan Zhang, Isha Sethi, Lincai Ye, Michael A. Trembley, Yangpo Cao, Brynn N. Akerberg, Feng Xiao, Xiaoran Zhang, Kai Li, Blake D. Jardin, Neil Mazumdar, Qing Ma, Aibin He, Bin Zhou, William T. Pu
Publikováno v:
Circulation research. 131(11)
Background: The pioneer transcription factor (TF) GATA4 (GATA Binding Protein 4) is expressed in multiple cardiovascular lineages and is essential for heart development. GATA4 lineage-specific occupancy in the developing heart underlies its lineage s
Autor:
Yuxuan Guo, Yangpo Cao, Blake D Jardin, Xiaoran Zhang, Pingzhu Zhou, Silvia Guatimosim, Junsen Lin, Zhan Chen, Yueyang Zhang, Neil Mazumdar, Fujian Lu, Qing Ma, Yao-Wei Lu, Mingming Zhao, Da-Zhi Wang, Erdan Dong, William T Pu
Publikováno v:
Cardiovasc Res
Calcium handling capacity is a major gauge of cardiomyocyte maturity. Ryanodine receptor 2 (RYR2) is the predominant calcium channel that releases calcium from the sarcoplasmic reticulum/endoplasmic reticulum (SR/ER) to activate cardiomyocyte contrac
Autor:
Suya Wang, Erika Yazawa, Erin M Keating, Neil Mazumdar, Alexander Hauschild, Qing Ma, Haiyan Wu, Yang Xu, Xu Shi, Douglas Strathdee, Robert E Gerszten, Michael Schlame, William T Pu
Publikováno v:
Human Molecular Genetics.
Barth syndrome is an X-linked disorder caused by loss-of-function mutations in Tafazzin (TAZ), an acyltransferase that catalyzes remodeling of cardiolipin, a signature phospholipid of the inner mitochondrial membrane. Patients develop cardiac and ske
Autor:
Pingzhu Zhou, Nathan J. VanDusen, Yanchun Zhang, Yangpo Cao, Isha Sethi, Rong Hu, Shuo Zhang, Guangyu Wang, Lincai Ye, Neil Mazumdar, Jian Chen, Xiaoran Zhang, Yuxuan Guo, Bin Li, Qing Ma, Julianna Y. Lee, Weiliang Gu, Guo-Cheng Yuan, Bing Ren, Kaifu Chen, William T. Pu
Publikováno v:
Developmental Cell. 58:898-914.e7
Publikováno v:
Microcirculation (New York, N.Y. : 1994)REFERENCES. 29(3)
The myogenic response sets the foundation for blood flow control. Recent findings suggest a role for G protein-coupled receptors (GPCR) and signaling pathways tied to the generation of reactive oxygen species (ROS). In this regard, this study ascerta
Autor:
Guo-Cheng Yuan, Yuxuan Guo, Eric M. Small, Qing Ma, Michael A. Trembley, Alan H. Beggs, Behzad Moghadaszadeh, Emily C Troiano, Blake D. Jardin, Yangpo Cao, Isha Sethi, Neil Mazumdar, William T. Pu
Publikováno v:
Proc Natl Acad Sci U S A
The paucity of knowledge about cardiomyocyte maturation is a major bottleneck in cardiac regenerative medicine. In development, cardiomyocyte maturation is characterized by orchestrated structural, transcriptional, and functional specializations that
Autor:
Suzanne E. Brett, Maria Sancho, Donald G. Welsh, Anil Zechariah, Neil Mazumdar, Rania E. Mufti
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35:2571-2578
Objective— The myogenic response is central to blood flow regulation in the brain. Its induction is tied to elevated cytosolic [Ca 2+ ], a response primarily driven by voltage-gated Ca 2+ channels and secondarily by Ca 2+ wave production. Although
Autor:
Anders Nygren, Ahmed M. Hashad, Donald G. Welsh, Kamran Bigdely-Shamloo, Sean M. Wilson, Jose L. Puglisi, Monica Romero, Edward J. Vigmond, Osama F. Harraz, Neil Mazumdar
Publikováno v:
The Journal of Physiology
The Journal of Physiology, 2017, 595 (4), pp.1111-1126. ⟨10.1113/JP273329⟩
The Journal of Physiology, Wiley, 2017, 595 (4), pp.1111-1126. ⟨10.1113/JP273329⟩
The Journal of Physiology, 2017, 595 (4), pp.1111-1126. ⟨10.1113/JP273329⟩
The Journal of Physiology, Wiley, 2017, 595 (4), pp.1111-1126. ⟨10.1113/JP273329⟩
Ca2+ sparks are generated in a voltage dependent manner to initiate spontaneous transient outward currents (STOC), events that moderate arterial constriction. In this study, we defined the mechanisms by which membrane depolarization increases Ca2+ sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d80a023aa1c0491b208673ca136a46
https://hal.science/hal-02885672
https://hal.science/hal-02885672