Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Neil MacRitchie"'
Autor:
Agnieszka Sagan, Tomasz P. Mikolajczyk, Wojciech Mrowiecki, Neil MacRitchie, Kevin Daly, Alan Meldrum, Serena Migliarino, Christian Delles, Karol Urbanski, Grzegorz Filip, Boguslaw Kapelak, Pasquale Maffia, Rhian Touyz, Tomasz J. Guzik
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Abdominal Aortic Aneurysm (AAA) is a major cause of cardiovascular mortality. Adverse changes in vascular phenotype act in concert with chronic inflammation to promote AAA progression. Perivascular adipose tissue (PVAT) helps maintain vascular homeos
Externí odkaz:
https://doaj.org/article/fbbdf7e078ea4de3a37774b6a2dfbbca
Autor:
Jonathan Noonan, Gianluca Grassia, Neil MacRitchie, Paul Garside, Tomasz J. Guzik, Angela C. Bradshaw, Pasquale Maffia
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Atherosclerosis is a complex inflammatory pathology underpinning cardiovascular diseases (CVD), which are the leading cause of death worldwide. The interplay between vascular stromal cells and immune cells is fundamental to the progression and outcom
Externí odkaz:
https://doaj.org/article/5dfcc9a1d25940f1b06bfc4cfc86fa26
Autor:
Junxi Wu, Gianluca Grassia, Helen Cambrook, Armando Ialenti, Neil MacRitchie, Jaclyn Carberry, Roger M. Wadsworth, Catherine Lawrence, Simon Kennedy, Pasquale Maffia
Publikováno v:
PeerJ, Vol 3, p e1192 (2015)
Objective. Emerging evidence suggests an important role for mast cells in vein graft failure. This study addressed the hypothesis that perivascular mast cells regulate in situ vascular inflammatory and proliferative responses and subsequent vein graf
Externí odkaz:
https://doaj.org/article/98c56c9518df49e3958466d9420532f6
Autor:
Neil MacRitchie, Pasquale Maffia, Miguel Ferreira, Valentina Di Francesco, Paolo Decuzzi, Tomasz J. Guzik
Publikováno v:
Seminars in immunology. 56
Theranostics, literally derived from the combination of the words diagnostics and therapy, is an emerging field of clinical and preclinical research, where contrast agents, drugs and diagnostic techniques are combined to simultaneously diagnose and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4dbc73de95cd5219249a7a1d2b1771
https://pubmed.ncbi.nlm.nih.gov/34862118
https://pubmed.ncbi.nlm.nih.gov/34862118
Autor:
Thomas D. Otto, Lucy McShane, Danila Gurgone, Gabrielle Paulsson-Berne, Gianluca Grassia, Mariola Kurowska-Stolarska, Neil MacRitchie, Abdullatif Mohammed Bin-Khunayn, Glykeria Karadimou, Pasquale Maffia, Eva Crespo, Tomasz J. Guzik, Peder S. Olofsson, Lorena Zentilin, Mauro Giacca
Publikováno v:
Basic science.
Introduction The TAM receptors (Tyro3, Axl, and MerTK) are a distinct family of three receptor tyrosine kinases, namely Tyro3, Axl and MerTK, which play critical roles in cancer, inflammatory disorders and cardiovascular diseases. Axl, in particular,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff9ff13a2c914370349802d61fb01c11
https://doi.org/10.1136/heartjnl-2021-bcs.223
https://doi.org/10.1136/heartjnl-2021-bcs.223
Autor:
Maciej Tomaszewski, Tomasz J. Guzik, Ryszard Nosalski, Eleanor Murray, Neil MacRitchie, Pasquale Maffia, David G. Harrison
Animal models, human observational and genetic studies have shown that immune and inflammatory mechanisms play a key role in hypertension and its complications. We review the effects of immunomodulatory interventions on blood pressure, target organ d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd58934688a33f99aa3721483f6cd69
http://hdl.handle.net/11588/880787
http://hdl.handle.net/11588/880787
Publikováno v:
British Journal of Pharmacology
Cardiovascular diseases (CVDs), including atherosclerosis, are chronic inflammatory diseases characterised by a complex and evolving tissue micro-environment. Molecular heterogeneity of inflammatory responses translates into clinical outcomes. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1ac354090a2561fced320ebc8f095e
https://pubmed.ncbi.nlm.nih.gov/34378206
https://pubmed.ncbi.nlm.nih.gov/34378206
Autor:
Pasquale Maffia, Neil MacRitchie
Publikováno v:
Cardiovasc Res
AIMS: Assessment of preclinical models of vascular disease is paramount in the successful translation of novel treatments. The results of these models have traditionally relied on two-dimensional (2D) histological methodologies. Light sheet fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a4e6d5a2954190438d931b0aed0d19
https://europepmc.org/articles/PMC7820857/
https://europepmc.org/articles/PMC7820857/
Autor:
Tristan Lawton, Atsuko Sugiyama, Neil MacRitchie, Marina Frleta-Gilchrist, Pasquale Maffia, Iain B. McInnes
Publikováno v:
Pharmacology & Therapeutics
Inflammation is a key factor in multiple diseases including primary immune-mediated inflammatory diseases e.g. rheumatoid arthritis but also, less obviously, in many other common conditions, e.g. cardiovascular disease and diabetes. Together, chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6edc3363f48f2be1b9143a4fa9ce7600
Autor:
Christoph Alexiou, Pasquale Maffia, Josbert M. Metselaar, Donald Bruce, Didier Letourneur, Iwona Cicha, Janos Szebeni, Cédric Chauvierre, Erik S.G. Stroes, Gert Storm, Neil MacRitchie, László Dézsi, Claudia Cabella, François Rouzet, Isabelle Texier
Publikováno v:
Cardiovascular Research
Cardiovascular Research, 2018, 114 (13), pp.1714-1727. ⟨10.1093/cvr/cvy219⟩
Cardiovascular research, 114(13), 1714-1727. Oxford University Press
Cardiovascular Research, Oxford University Press (OUP), 2018, 114 (13), pp.1714-1727. ⟨10.1093/cvr/cvy219⟩
Cardiovascular Research, 114(13), 1714. Oxford University Press
Cardiovascular Research, 2018, 114 (13), pp.1714-1727. ⟨10.1093/cvr/cvy219⟩
Cardiovascular research, 114(13), 1714-1727. Oxford University Press
Cardiovascular Research, Oxford University Press (OUP), 2018, 114 (13), pp.1714-1727. ⟨10.1093/cvr/cvy219⟩
Cardiovascular Research, 114(13), 1714. Oxford University Press
Cardiovascular diseases (CVD) account for nearly half of all deaths in Europe and almost 30% of global deaths. Despite the improved clinical management, cardiovascular mortality is predicted to rise in the next decades due to the increasing impact of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7730fee9272e758f619b2e693b916e3b
https://doi.org/10.1093/cvr/cvy219
https://doi.org/10.1093/cvr/cvy219