Assessment of the sensitizing potential of processed peanut proteins in Brown Norway rats: roasting does not enhance allergenicity.

Autor: Stine Kroghsbo, Neil M Rigby, Philip E Johnson, Karine Adel-Patient, Katrine L Bøgh, Louise J Salt, E N Clare Mills, Charlotte B Madsen

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96475 (2014)

BACKGROUND: IgE-binding of process-modified foods or proteins is the most common method for examination of how food processing affects allergenicity of food allergens. How processing affects sensitization capacity is generally studied by administrati

Externí odkaz: https://doaj.org/article/3cd15df9666f4bc68996910d9b1ef84e

Microbial transglutaminase alters the immunogenic potential and cross-reactivity of horse and cow milk proteins

Autor: Barbara Wróblewska, Joanna Fotschki, Bartosz Fotschki, Neil M. Rigby, Bolesław Kalicki, Alan R. Mackie

Publikováno v: Journal of Dairy Science. 103:2153-2166

Horse milk is a valuable raw material and a very attractive alternative for scientific research to address the issue of cow milk (CM) allergy due to its protein profile. A decrease in immunoreactive properties can be achieved by thermal, enzymatic, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c597ec9f2796bad55dfc3e4d20855b74
https://doi.org/10.3168/jds.2019-17264

Isolation and Characterization of Wheat Derived Nonspecific Lipid Transfer Protein 2 (nsLTP2)

Autor: Marina Naldi, Sara Bosi, Silvana Hrelia, Cecilia Prata, Neil M. Rigby, Luca Massaccesi, Ilaria Marotti, Roberto Gotti, Marco Malaguti, Valeria Bregola, Emanuela Leoncini, Paul A. Kroon, Giovanni Dinelli, Jessica Fiori

Publikováno v: Journal of Food Science. 83:1516-1521

Numerous studies support the protective role of bioactive peptides against cardiovascular diseases. Cereals represent the primary source of carbohydrates, but they also contain substantial amounts of proteins, therefore representing a potential dieta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c9a9b89d7ab5d1b543a1c8552367a79
https://doi.org/10.1111/1750-3841.14175

Study on the digestion of milk with prebiotic carbohydrates in a simulated gastrointestinal model

Autor: Antonia Montilla, Alvaro Ferreira-Lazarte, Neil M. Rigby, Agustín Olano, Alan R. Mackie, Ana-Isabel Mulet-Cabero, Mar Villamiel

Publikováno v: Journal of Functional Foods, Vol 33, Iss, Pp 149-154 (2017)
Digital.CSIC. Repositorio Institucional del CSIC
instname

The behaviour of oligosaccharides from lactulose (OsLu) included with milk was examined during in vitro gastrointestinal digestion using the Infogest protocol as well as some small intestine rat extract. The digestion was compared with commercial pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fb08dcb981f1c14b16b2c8de24b0b9
https://doi.org/10.1016/j.jff.2017.03.031

Rational Design, Structure–Activity Relationship, and Immunogenicity of Hypoallergenic Pru p 3 Variants

Autor: Montserrat Fernandez-Rivas, Bettina M. Jensen, Josef Laimer, Gabriele Gadermaier, Isabel Pablos, Antonio Portolés, Fatima Ferreira, Laurian Jongejan, Juan A. Asturias, Serge A. Versteeg, Lars K. Poulsen, Nikolaos G. Papadopoulos, Peter Briza, Adriano Mari, Markus Steiner, Neil M. Rigby, Angelika Hörschläger, Peter Lackner, Stephanie Pauline Eichhorn, Ronald van Ree

Publikováno v: Molecular Nutrition & Food Research
Eichhorn, S, Hörschläger, A, Steiner, M, Laimer, J, Jensen, B M, Versteeg, S A, Pablos, I, Briza, P, Jongejan, L, Rigby, N, Asturias, J A, Portolés, A, Fernandez-Rivas, M, Papadopoulos, N G, Mari, A, Poulsen, L K, Lackner, P, van Ree, R, Ferreira, F & Gadermaier, G 2019, ' Rational Design, Structure-Activity Relationship, and Immunogenicity of Hypoallergenic Pru p 3 Variants ', Molecular Nutrition & Food Research, vol. 63, no. 18, e1900336 . https://doi.org/10.1002/mnfr.201900336
Eichhorn, S, Hörschläger, A, Steiner, M, Laimer, J, Jensen, B M, Versteeg, S A, Pablos, I, Briza, P, Jongejan, L, Rigby, N, Asturias, J A, Portolés, A, Fernandez-Rivas, M, Papadopoulos, N G, Mari, A, Poulsen, L K, Lackner, P, van Ree, R, Ferreira, F & Gadermaier, G 2019, ' Rational Design, Structure–Activity Relationship, and Immunogenicity of Hypoallergenic Pru p 3 Variants ', Molecular Nutrition and Food Research . https://doi.org/10.1002/mnfr.201900336
Molecular nutrition & food research. Wiley-VCH Verlag

Scope Allergies to lipid transfer proteins involve severe adverse reactions; thus, effective and sustainable therapies are desired. Previous attempts disrupting disulfide bonds failed to maintain immunogenicity; thus, the aim is to design novel hypoa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b9a9ac0b1ad05f26ead459a26cbba7
http://europepmc.org/articles/PMC6790652