Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Neil L. A. Misso"'
Autor:
Svetlana Baltic, Cornelia M. Bertram, Philip J. Thompson, Rosalind Gulliver, Neil L. A. Misso, Mirjana Fogel-Petrovic
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 45:542-549
This study tested the hypothesis that proinflammatory kinin peptides are involved in modulating human dendritic cell (DC) function. Inflammation is accompanied by an increased maturation of DCs and the generation of kinins, particularly Lys-des[Arg(9
Publikováno v:
Current Pharmacogenomics and Personalized Medicine. 7:133-145
Publikováno v:
International Archives of Allergy and Immunology. 149:127-132
Background: Wine-induced asthmatic symptoms may be caused by sulphite additives. Prostaglandin (PG)D2 and cysteinyl leukotrienes (cysLT) are important mediators of asthmatic responses. To determine whether the sulphite additives in wine alter the pro
Autor:
Kanti D. Bhoola, Philip J. Thompson, Anupam Naran, Neil L. A. Misso, Daniel R Langlands, Bilkish Cassim, Odette M. Shaw, Margaret Mazur
Publikováno v:
Rheumatology. 48:490-496
Objectives. Neutrophils traffic into and have the capacity to generate kinins in SF of RA patients. The aim of this study was to assess the expression of kallikreins, kininogens and kinin receptors in circulating and SF neutrophils, as well as synovi
Autor:
Paul S. Foster, Mirjana Fogel-Petrovic, Neil L. A. Misso, Carlos D. Figueroa, Cornelia M. Bertram, Kanti D. Bhoola, Philip J. Thompson
Publikováno v:
Journal of Leukocyte Biology. 85:544-552
Eosinophils contribute to asthmatic airway inflammation by releasing cysteinyl leukotrienes (cysLT) and other inflammatory mediators, and bradykinin (BK) induces bronchoconstriction in asthmatic patients. The aims of this study were to investigate ki
Autor:
Neil L. A. Misso, Mary-Anne Kedda, Carolyn Williams, Philip J. Thompson, David L. Duffy, Mat Welch, J. Shi, J. Horn
Publikováno v:
Clinical & Experimental Allergy. 38:913-920
Background Cyclooxygenase (COX)-2 is an inducible enzyme responsible for catalysing the formation of prostaglandins (PGs) in settings of inflammation. Single nucleotide polymorphisms (SNPs) of the COX-2 gene may influence gene transcription and PG pr
Autor:
Neil L. A. Misso, Jasmine Singh, Philip J. Thompson, Anupam Naran, Kanti D. Bhoola, Paul Rigby
Publikováno v:
International Immunopharmacology. 8:300-306
Lung cancer is currently the leading cause of cancer mortality worldwide. Expression of kallikrein-related peptidases (KRP/hK/KLK) may be induced during lung carcinogenesis. To test the hypothesis that KRP/hK, previously identified in the skin (KRP/h
Autor:
Anthony Celenza, Nenad Petrovic, Carolyn S. Grove, Philip J. Thompson, Neil L. A. Misso, Joanne Brooks-Wildhaber
Publikováno v:
Thorax. 63:21-26
Background: Secretory phospholipases A2 (sPLA2) have functions relevant to asthmatic inflammation, including eicosanoid synthesis and effects on dendritic cells and T cells. The aim of this study was to measure sPLA2 activity in patients with stable
Autor:
Kanti D. Bhoola, Philip J. Thompson, Neil L. A. Misso, Cornelia M. Bertram, Carlos D. Figueroa, Mirjana Fogel-Petrovic
Publikováno v:
International Immunopharmacology. 7:1862-1868
Kinins have been implicated in the pathophysiology of asthma and activation of kinin receptors stimulates neutrophil chemotaxis. However, the expression of kinin receptors on neutrophils of asthmatic subjects has not been assessed. The aim of this st
Autor:
Jessica Chee, Neil L. A. Misso, Philip J. Thompson, Jasmine Singh, Anupam Naran, Kanti D. Bhoola
Publikováno v:
bchm. 388:1235-1242
Malignant mesothelioma is an aggressive cancer of the pleura that is causally related to exposure to asbestos fibres. The kallikrein serine proteases [tissue (hK1) and plasma (hKB1) kallikreins, and kallikrein-related peptidases (KRP/hK2–15)] and t