Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Neil J. Howell"'
Publikováno v:
The Journal of Vascular Access. 20:760-762
Left ventricular assist devices are used in heart failure patients as bridge to transplantation or increasingly as a destination therapy. These patients frequently have renal dysfunction and many reach end-stage renal failure. If haemodialysis is req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f9026c0e7e9f7bbba9f63271e562b38
https://doi.org/10.1177/1129729819826029
https://doi.org/10.1177/1129729819826029
Autor:
Lisa C Heather, Neil J Howell, Yaso Emmanuel, Mark A Cole, Michael P Frenneaux, Domenico Pagano, Kieran Clarke
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26326 (2011)
In the hypertrophied human heart, fatty acid metabolism is decreased and glucose utilisation is increased. We hypothesized that the sarcolemmal and mitochondrial proteins involved in these key metabolic pathways would mirror these changes, providing
Externí odkaz:
https://doaj.org/article/baf0ec011cbe4aa2b81c1078baf87b53
Publikováno v:
Journal of Cardiac Failure. 23:169-180
The use of left ventricular assist devices (LVADs) has increased significantly over the past few years, in part because heart transplant activity has plateaued, but also because of the improving clinical outcomes with contemporary continuous-flow LVA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d889b7451c7f882703cbf254a852054
https://doi.org/10.1016/j.cardfail.2016.10.015
https://doi.org/10.1016/j.cardfail.2016.10.015
Autor:
Julian L. Griffin, John French, Nikhil Pal, Parisa Yavari, Rina Ariga, William T.E. Briggs, Tim Dent, Masliza Mahmod, Arash Yavari, Houman Ashrafian, Mark Cassar, John D. Horowitz, Jeremy S Dwight, Zsuzsanna Ament, James A. West, Bernard D. Prendergast, David L Hare, Anthony C Keech, Animesh Acharjee, Hugh Watkins, Kate S. Elliott, Helen Lockstone, Rajesh K. Kharbanda, Violetta Steeples, Michael P. Frenneaux, Neil J. Howell, Mark Richards, Thanh H Nguyen, Steven Unger
Background Aortic stenosis (AS) and hypertrophic cardiomyopathy (HCM) are highly distinct disorders leading to LVH, but whether cardiac metabolism substantially differs between these in humans remains to be elucidated. Method We undertook a detailed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c7ba587786330e5d739faf53a4c95e
https://doi.org/10.1101/715680
https://doi.org/10.1101/715680
Publikováno v:
ASAIO journal (American Society for Artificial Internal Organs : 1992). 65(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec4b75ca35580f867cf1bfd9b53e90fb
https://pubmed.ncbi.nlm.nih.gov/30074966
https://pubmed.ncbi.nlm.nih.gov/30074966
Autor:
Miguel Sousa-Uva, Domenico Pagano, Joel Dunning, Matthias Thielmann, Neil J. Howell, Giuseppe Cardillo, Manuel Castellá, Tomas Gudbjartsson, Umberto Benedetto, Philippe Kolh, Martin Czerny, A. Pieter Kappetein, Mark G. Hazekamp, Stuart J. Head, Friedhelm Beyersdorf
Publikováno v:
European Journal of Cardio-thoracic Surgery, 48(6), 809-816. Elsevier
European Journal of Cardio-Thoracic Surgery, 48(6), 809-816
European Journal of Cardio-Thoracic Surgery, 48(6), 809-816
The goal of all clinical guidelines is to assist patients and practitioners in making healthcare decisions. However, clinical guidelines have been questioned about their quality, transparency and independence. Based on the revision of manuals by othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff1be93703341f730266da1e434771d
https://doi.org/10.1093/ejcts/ezv309
https://doi.org/10.1093/ejcts/ezv309
Autor:
Timothy R. Graham, Michael E. Lewis, Nick Freemantle, Ian C. Wilson, Jorge Mascaro, Stephen J. Rooney, Nigel E Drury, David H. Green, Eshan L Senanayake, Neil J. Howell, Michael P. Frenneaux, Sunil K. Bhudia, Aaron M. Ranasinghe, Tessa Oelofse, Domenico Pagano
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 48:354-362
Patients undergoing cardiac surgery require adequate myocardial protection. Manipulating myocardial metabolism may improve the extent of myocardial protection. Perhexiline has been shown to be an effective anti-anginal agent due to its metabolic modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66346a6c3f8887913726fd6c3d2904d
https://doi.org/10.1093/ejcts/ezu452
https://doi.org/10.1093/ejcts/ezu452
Autor:
John H. Dark, Neil J. Howell, Ioannis Dimarakis, Marius Berman, Ha Sum Esther Wong, Rajamiyer Venkateswaran, Nicholas R. Banner, John R. Payne, Jenny Mehew, Sally Rushton
Publikováno v:
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 53(6)
OBJECTIVES The optimum time after brainstem death (BSD) at which to assess the function of donor hearts is unknown. We hypothesized that a longer interval may be associated with a higher transplantation rate due to improved function. METHODS Data wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d3b9ac58613e0ddca722652b1fcb3c
https://pubmed.ncbi.nlm.nih.gov/29370400
https://pubmed.ncbi.nlm.nih.gov/29370400
Autor:
Eshan L Senanayake, Domenico Pagano, Stephen J. Rooney, Jorge Mascaro, Daniel Ray, Ian C. Wilson, Neil J. Howell, Timothy Graham
Publikováno v:
Asian Cardiovascular and Thoracic Annals. 23:11-16
Aim Late failure of bioprosthetic valves may limit their use in patients Methods Patients who underwent aortic valve replacement with or without coronary artery bypass grafting between July 1997 and January 2010 with Carbomedics supraannular Top Hat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9513dff04acd637bbbfe809da99cf7fd
https://doi.org/10.1177/0218492314529954
https://doi.org/10.1177/0218492314529954
Autor:
Nigel E. Drury, Cher-Rin Chong, Domenico Pagano, Michael P. Frenneaux, John D. Horowitz, Benedetta C. Sallustio, Neil J. Howell, Giovanni Licari
Publikováno v:
British Journal of Clinical Pharmacology. 77:789-795
Little is known regarding the steady-state uptake of drugs into the human myocardium. Perhexiline is a prophylactic anti-anginal drug which is increasingly also used in the treatment of heart failure and hypertrophic cardiomyopathy. We explored the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fde8b44f3be2c3d2311d8a31b4c067e
https://doi.org/10.1111/bcp.12254
https://doi.org/10.1111/bcp.12254