Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Neil J. Hounslow"'
Autor:
Henry N. Ginsberg, Neil J. Hounslow, Yusuke Senko, Hideki Suganami, Pawel Bogdanski, Richard Ceska, Akos Kalina, Roman A. Libis, Tatiana V. Supryadkina, G. Kees Hovingh
Publikováno v:
Diabetes care, 45(4), 898-908. American Diabetes Association Inc.
OBJECTIVE High plasma triglyceride (TG) is an independent risk factor for cardiovascular disease. Fibrates lower TG levels through peroxisome proliferator–activated receptor α (PPARα) agonism. Currently available fibrates, however, have relativel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f181e69a767b7adc7c8d8f4d2aa30c9
https://doi.org/10.2337/figshare.18028304
https://doi.org/10.2337/figshare.18028304
Autor:
Bing Bing Yang, Robert B. Abel, Mark MacMahon, Neil J. Hounslow, Stephen C. Olson, Ralph H. Stern
Publikováno v:
The Journal of Clinical Pharmacology. 40:616-623
The objective of this study is to determine the relationships between plasma atorvastatin concentrations, LDL (low-density lipoprotein) cholesterol reduction, and atorvastatin dose; the earliest time at which lipid levels change when atorvastatin tre
Publikováno v:
The Journal of Clinical Pharmacology. 36:356-360
Possible effects of multiple-dose administration of atorvastatin on the pharmacokinetics of single-dose antipyrine were evaluated in this drug-drug interaction study. Twelve healthy male volunteers received three 200-mg capsules of antipyrine on days
Autor:
Christine Alvey, Neil J. Hounslow, George Rausch, Allen J. Sedman, Edward J. Randinitis, Nicola J. Bron, Jeffery R. Koup, Robert Abel, Artemios B. Vassos
Many fluoroquinolone antibiotics are inhibitors of cytochrome P450 enzyme systems and may produce potentially important drug interactions when administered with other drugs. Studies were conducted to determine the effect of clinafloxacin on the pharm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f266c2298c8ee437c267e39a0bad45f0
https://europepmc.org/articles/PMC90690/
https://europepmc.org/articles/PMC90690/
Autor:
George Rausch, Nicola J. Bron, Allen J. Sedman, Edward J. Randinitis, Neil J. Hounslow, Jeffery R. Koup, Robert Abel, Artemios B. Vassos
As the primary route for elimination of clinafloxacin is renal clearance (CL R ) of unchanged drug, studies were conducted to determine the pharmacokinetic profile of clinafloxacin following administration to young and elderly subjects, subjects with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8622350735e505d36e18561d5d513bf
https://europepmc.org/articles/PMC90689/
https://europepmc.org/articles/PMC90689/
Autor:
Lloyd R. Whitfield, Allen J. Sedman, Alan Richens, Neil J. Hounslow, Donald M. Gibson, Nicola J. Bron
Publikováno v:
Journal of clinical pharmacology. 36(3)
Atorvastatin is a new 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor that reduces plasma cholesterol by inhibiting cholesterol synthesis and increasing cellular uptake of low density lipoproteins. The effects of age and gender on