Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Neil J Oldfield"'
Autor:
Eduardo Rojas, Johanna Hoyos, Neil J Oldfield, Philip Lee, Mike Flint, C Hal Jones, Dlawer A A Ala'Aldeen, Kathrin U Jansen, Annaliesa S Anderson
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132140 (2015)
The reservoir for Neisseria meningitidis (Nm) is the human oropharynx. Implementation of Nm serogroup C (NmC) glycoconjugate vaccines directly reduced NmC carriage. Prophylactic vaccines are now available to prevent disease caused by the five major N
Externí odkaz:
https://doaj.org/article/36a9d7ded5454c5bac50ee98e296e884
Autor:
Neil J Oldfield, Suzan Matar, Fadil A Bidmos, Mohammed Alamro, Keith R Neal, David P J Turner, Christopher D Bayliss, Dlawer A A Ala'aldeen
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69746 (2013)
Neisseria meningitidis is a human nasopharyngeal commensal capable of causing life-threatening septicemia and meningitis. Many meningococcal surface structures, including the autotransporter proteins NalP and MspA, are subject to phase variation (PV)
Externí odkaz:
https://doaj.org/article/9843899e88734535bc4a8ea67087be38
Autor:
Noha M Abouseada, Mahde Saleh A Assafi, Jafar Mahdavi, Neil J Oldfield, Lee M Wheldon, Karl G Wooldridge, Dlawer A A Ala'Aldeen
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46233 (2012)
Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumoniae are major bacterial agents of meningitis. They each bind the 37/67-kDa laminin receptor (LamR) via the surface protein adhesins: meningococcal PilQ and PorA, H. influenzae Om
Externí odkaz:
https://doaj.org/article/fec9ce300b154828a3f36c6ebc13dda3
Autor:
Jennifer C. Okoye, Alexandria Holland, Matthaios Pitoulias, Vasileios Paschalis, Artem Piddubnyi, Osman A. Dufailu, Thomas Borén, Neil J. Oldfield, Jafar Mahdavi, Panos Soultanas
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Campylobacter jejuni colonizes hosts by interacting with Blood Group Antigens (BgAgs) on the surface of gastrointestinal epithelia. Genetic variations in BgAg expression affects host susceptibility to C. jejuni. Here, we show that the essential major
Externí odkaz:
https://doaj.org/article/c84216198c4f45a196212118ed939b0b
Autor:
Matthew Vassey, Rininta Firdaus, Akhmed Aslam, Lee M. Wheldon, Neil J. Oldfield, Dlawer A. A. Ala’Aldeen, Karl G. Wooldridge
Publikováno v:
Cellular Microbiology, Vol 2023 (2023)
Neisseria meningitidis is the most frequent cause of bacterial meningitis and is one of the few bacterial pathogens that can breach the blood-brain barrier (BBB). The 37/67 kDa laminin receptor (LamR) was previously identified as a receptor mediating
Externí odkaz:
https://doaj.org/article/80812655905a4ffbb15e7e36e8d17994
Autor:
Neelam Dave, Raed S. Albiheyri, Joseph J. Wanford, Luke R. Green, Neil J. Oldfield, David P. J. Turner, Luisa Martinez-Pomares, Christopher D. Bayliss
Publikováno v:
Microbiology. 169
Colonization of mucosal tissues by Neisseria meningitidis requires adhesion mediated by the type IV pilus and multiple outer-membrane proteins. Penetration of the mucosa and invasion of epithelial cells are thought to contribute to host persistence a
Autor:
Jennifer C. Okoye, Jeddidiah Bellamy-Carter, Neil J. Oldham, Neil J. Oldfield, Jafar Mahdavi, Panos Soultanas
Publikováno v:
Computational and Structural Biotechnology Journal. 20:5355-5363
Ferric chelates like ferric tyrosinate (TYPLEX) and the closely related ferric quinate (QPLEX) are structural mimics of bacterial siderophores. TYPLEX has been trialled as a feed additive in farming of commercial broilers, reducing Campylobacter load
Autor:
Robert H Shaw, Xinxue Liu, Arabella S V Stuart, Melanie Greenland, Parvinder K Aley, Nick J Andrews, J Claire Cameron, Sue Charlton, Elizabeth A Clutterbuck, Andrea M Collins, Wanwisa Dejnirattisai, Tanya Dinesh, Saul N Faust, Daniela M Ferreira, Adam Finn, Christopher A Green, Bassam Hallis, Paul T Heath, Helen Hill, Teresa Lambe, Rajeka Lazarus, Vincenzo Libri, Fei Long, Yama F Mujadidi, Emma L Plested, Ella R Morey, Samuel Provstgaard-Morys, Maheshi N Ramasamy, Mary Ramsay, Robert C Read, Hannah Robinson, Gavin R Screaton, Nisha Singh, David P J Turner, Paul J Turner, Iason Vichos, Laura L Walker, Rachel White, Jonathan S Nguyen-Van-Tam, Matthew D Snape, Alasdair P.S. Munro, Jazz Bartholomew, Laura Presland, Sarah Horswill, Sarah Warren, Sophie Varkonyi-Clifford, Stephen Saich, Kirsty Adams, Marivic Ricamara, Nicola Turner, Nicole Y. Yee Ting, Sarah Whittley, Tommy Rampling, Amisha Desai, Claire H. Brown, Ehsaan Qureshi, Karishma Gokani, Kush Naker, Johanna K. Kellett Wright, Rachel L. Williams, Tawassal Riaz, Florentina D. Penciu, Amy Carson, Claudio Di Maso, Gracie Mead, Elizabeth G. Howe, Mujtaba Ghulam Farooq, Rabiullah Noristani, Xin L. Yao, Neil J. Oldfield, Daniel Hammersley, Sue Belton, Simon Royal, Alberto San Francisco Ramos, Cecilia Hultin, Eva P. Galiza, Rebecca Crook, Marcin Bula, Fred Fyles, Hassan Burhan, Flora Maelin, Elen Hughes, Emmanuel Okenyi
Publikováno v:
Shaw, R H, Liu, X, Stuart, A S V, Greenland, M, Aley, P K, Andrews, N J, Finn, A & Lazarus, R & et, A 2022, ' Effect of priming interval on reactogenicity, peak immunological response, and waning after homologous and heterologous COVID-19 vaccine schedules : exploratory analyses of Com-COV, a randomised control trial ', Lancet Respiratory Medicine, vol. 10, no. 11, pp. 1049-1060 . https://doi.org/10.1016/S2213-2600(22)00163-1
Background Priming COVID-19 vaccine schedules have been deployed at variable intervals globally, which might influence immune persistence and the relative importance of third-dose booster programmes. Here, we report exploratory analyses from the Com-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed4ea510bf1be44fbc2afbfb9cf0590
https://eprints.soton.ac.uk/456454/
https://eprints.soton.ac.uk/456454/
Autor:
Ayushi Ramjee, Chloe Ogilvie, Africa Couto, Teresa Matini, Claudia Anaele, Sylwia Bujkiewicz, Neil J Oldfield, David PJ Turner, Christopher David Bayliss
ObjectivesUniversity student cohorts have a potential for significant impacts on public health policies. Health impacts arise from wide geographic catchment areas and behavioural patterns that enhance infectious disease spread and occasional cases of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3fb39968a5f473ff9b650948ac37eb9
https://doi.org/10.31219/osf.io/zsrt5
https://doi.org/10.31219/osf.io/zsrt5
Autor:
Sophie Varkonyi-Clifford, Sue Charlton, Anna England, Matthew D. Snape, Parvinder K. Aley, Elizabeth A. Clutterbuck, Pauline Ambrose, Eva P. Galiza, Adam Finn, Laura L. Walker, Emma Plested, Ehsaan Qureshi, Chanice Knight, David P. J. Turner, Lisa Hitchins, Mujtaba Ghulam Farooq, Christopher A Green, Melanie Greenland, J. Claire Cameron, Stephanie Leung, Karen Buttigieg, Jonathan S. Nguyen-Van-Tam, Cecilia Hultin, Florentina D Penciu, Jazz Bartholomew, Yama F Mujadidi, Nisha Singh, Sarah Horswill, Tommy Rampling, Kush Naker, Rabiullah Noristani, Xinxue Liu, Marivic Ricamara, Tawassal Riaz, Phill Brown, Rajeka Lazarus, Imam Shaik, Johanna K Kellett Wright, Kerry Godwin, Kelly Davies, Robert Shaw, Paminder Lall, Neil J. Oldfield, Farah Shiham, Sue Belton, Karishma Gokani, Carla Solórzano, Mary Ramsay, Kirsty Adams, Ross Fothergill, Hannah Robinson, Claudio Di Maso, Rachel Williams, Lauren Allen, Paul T. Heath, Sarah Whittley, Stephen Saich, E Howe, Bassam Hallis, Alberto San Francisco Ramos, Simon Royal, Alasdair Munro, Tanya Dinesh, Vincenzo Libri, Helen Hill, Arabella Stuart, Samuel Provstgaard-Morys, Xin L Yao, Andrea M. Collins, Rachel White, Paul Turner, Teresa Lambe, Nick Andrews, Iason Vichos, Daniela M. Ferreira, Natalie Baker, Nicole Y Yee Ting, Claire Brown, M N Ramasamy, Sarah Warren, Amisha Desai, Fei Long, Laura Presland, Hannah Sainsbury, Daniel Hammersley, Saul N. Faust, Robert C. Read, Nicola Turner
Publikováno v:
Lancet (London, England)
Snape, M D 2021, ' Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV) : a single-blind, randomised, non-inferiority trial ', Lancet, vol. 398, no. 10303, pp. 856-869 . https://doi.org/10.1016/S0140-6736(21)01694-9
Snape, M D 2021, ' Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV) : a single-blind, randomised, non-inferiority trial ', Lancet, vol. 398, no. 10303, pp. 856-869 . https://doi.org/10.1016/S0140-6736(21)01694-9
Background Use of heterologous prime-boost COVID-19 vaccine schedules could facilitate mass COVID-19 immunisation. However, we have previously reported that heterologous schedules incorporating an adenoviral vectored vaccine (ChAdOx1 nCoV-19, AstraZe