Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Neil J, Wells"'
Autor:
Bruno Linclau, Jean-Baptiste Vendeville, Clement Q. Fontenelle, Robert Szpera, Mark E. Light, Ramakrishna Kuppala, Edward L Briggs, David E Wheatley, Neil J. Wells
Protein-carbohydrate interactions are implicated in many biochemical/biological processes that are fundamental to life and to human health. Fluorinated carbohydrate analogues play an important role in the study of these interactions and find applicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7084be9f42955cdf4ef449719b539715
https://eprints.soton.ac.uk/450092/
https://eprints.soton.ac.uk/450092/
Autor:
David E, Wheatley, Clement Q, Fontenelle, Ramakrishna, Kuppala, Robert, Szpera, Edward L, Briggs, Jean-Baptiste, Vendeville, Neil J, Wells, Mark E, Light, Bruno, Linclau
Publikováno v:
The Journal of organic chemistry. 86(11)
Protein-carbohydrate interactions are implicated in many biochemical/biological processes that are fundamental to life and to human health. Fluorinated carbohydrate analogues play an important role in the study of these interactions and find applicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de605cea69bd18ea52ed43c7397e7b94
https://pubmed.ncbi.nlm.nih.gov/34029099
https://pubmed.ncbi.nlm.nih.gov/34029099
Publikováno v:
Supramolecular Chemistry. 30:286-295
Herein, we present the synthesis of a thymine nucleobase appended ‘frustrated’ monomer, which exhibits self-association in DMSO solutions through the formation of hydrogen bonds. This self-association process has been explored in both competitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad67ed326fa5d69531ec4d640f487dcf
https://doi.org/10.1080/10610278.2017.1351613
https://doi.org/10.1080/10610278.2017.1351613
Autor:
Zhong, Wang, Benjamin F, Jeffries, Hannah R, Felstead, Neil J, Wells, Elisabetta, Chiarparin, Bruno, Linclau
Publikováno v:
Journal of visualized experiments : JoVE. (143)
Fluorination has become an effective tool to optimize physicochemical properties of bioactive compounds. One of the applications of fluorine introduction is to modulate the lipophilicity of the compound. In our group, we are interested in the study o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8e8d72ddbeab443cc700e4c1227933b
https://pubmed.ncbi.nlm.nih.gov/30774129
https://pubmed.ncbi.nlm.nih.gov/30774129
Autor:
Neil J. Wells, Bruno Linclau, Zhong Wang, Hannah R Felstead, Elisabetta Chiarparin, Benjamin Jeffries
Publikováno v:
Journal of Visualized Experiments.
Fluorination has become an effective tool to optimize physicochemical properties of bioactive compounds. One of the applications of fluorine introduction is to modulate the lipophilicity of the compound. In our group, we are interested in the study o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e4c526bc6c0cc7e9bd9b156c1e1bc7
https://doi.org/10.3791/58567
https://doi.org/10.3791/58567
Publikováno v:
Liquid Crystals
In this article, we explore those factors that influence the orientational order in both nematic and twist-bend nematic phases. The systems used for our NMR experiments are binary mixtures of a dimer and a related monomer thus enabling its behaviour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce8c85b98a94dc8ae053a0c636ad470c
https://eprints.soton.ac.uk/428373/
https://eprints.soton.ac.uk/428373/
Publikováno v:
Organic & Biomolecular Chemistry. 14:9560-9567
A series of neutral ditopic and negatively charged, monotopic host molecules have been evaluated for their ability to bind chloride and dihydrogen phosphate anions, and neutral organophosphorus species dimethyl methylphosphonate (DMMP), pinacolyl met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07543664c553ea9bce6684315e8ec2a9
https://doi.org/10.1039/c6ob01210h
https://doi.org/10.1039/c6ob01210h
Autor:
Clement Q. Fontenelle, Neil J. Wells, Nicolas Galland, Bruno Linclau, Zhong Wang, Elena Bogdan, Jérôme Graton, Jean-Yves Le Questel, Florent Peron, Guillaume Compain
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Fluorination is commonly exercised in compound property optimization. However, the influence of fluorination on hydrogen-bond (HB) properties of adjacent functional groups, as well as the HB-accepting capacity of fluorine itself, is still not complet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f5482749f89c61209e30feec9134e1
https://doi.org/10.1002/chem.201503253
https://doi.org/10.1002/chem.201503253
Publikováno v:
Journal of the American Chemical Society. 137:1476-1484
We report a dynamic covalent approach to transmembrane transport of amino acids by the formation of a three-component assembly. A mixture of a squaramide and a lipophilic and electrophilic aldehyde is shown to synergistically transport highly polar g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d0b61ac5cde082689a7d02eebbd6e1
https://doi.org/10.1021/ja510063n
https://doi.org/10.1021/ja510063n
Publikováno v:
Journal of Materials Chemistry A. 3:1230-1234
The chemical warfare agent (CWA) soman (GD) acts as a molecular stimulus for the disruption of an anthracene-based binary organogel prepared in cyclohexane. The CWA simulants dimethyl methylphosphonate (DMMP) and diethyl chlorophosphate (DCP) were al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e233cd0d252a40ebe2ee01e4e220d6
https://doi.org/10.1039/c4ta04834b
https://doi.org/10.1039/c4ta04834b