Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Neil J, Shimwell"'
Autor:
Nafiseh, Chalabi Hagkarim, Ellis L, Ryan, Philip J, Byrd, Robert, Hollingworth, Neil J, Shimwell, Angelo, Agathanggelou, Manon, Vavasseur, Viktoria, Kolbe, Thomas, Speiseder, Thomas, Dobner, Grant S, Stewart, Roger J, Grand
Publikováno v:
Journal of Virology
Infection by most DNA viruses activates a cellular DNA damage response (DDR), which may be to the detriment or advantage of the virus. In the case of adenoviruses, they neutralize antiviral effects of DDR activation by targeting a number of proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22e87554708b3674196626fc2f514be6
https://pubmed.ncbi.nlm.nih.gov/29593045
https://pubmed.ncbi.nlm.nih.gov/29593045
Autor:
Y C Miki, Wenbin Wei, Olga Tucker, L Pallan, Neil J. Shimwell, Janet Morse, Yasuhiko Mohri, T. Mohri, Douglas G. Ward, M Teng, Masato Kusunoki, Philip J. Johnson
Publikováno v:
British Journal of Cancer
Background: There is a need for sensitive and specific blood-borne markers for the detection of gastric cancer. Raised serum macrophage inhibitory factor (MIF) levels have been proposed as a marker for gastric cancer diagnosis but, to date, studies h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9bd980d9ecd8fb2da8259f50340c18
http://europepmc.org/articles/PMC3493758
http://europepmc.org/articles/PMC3493758
Autor:
Christopher McCabe, Thomas Dobner, Peter Groitl, Andrew S. Turnell, Natalie A. Forrester, Rakesh N. Patel, Robert Seed, Garry G. Sedgwick, Roger J.A. Grand, Ashley Martin, Pól Ó Catnaigh, Neil J. Shimwell, Thomas Speiseder, Grant S. Stewart
Publikováno v:
Journal of Virology. 86:3167-3179
The ability of adenovirus early region proteins, E1B-55K and E4orf6, to usurp control of cellular ubiquitin ligases and target proteins for proteasome-dependent degradation during infection is well established. Here we show that the E4 gene product,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e178eecb469d81d77092ea5efa5469
https://doi.org/10.1128/jvi.06583-11
https://doi.org/10.1128/jvi.06583-11
Autor:
Wenbin Wei, Neil J. Shimwell, Michael J.O. Wakelam, Sue Wilson, Tariq Ismail, Douglas G. Ward, Ashley Martin, Tariq Iqbal, Philip J. Johnson
Publikováno v:
Cancer Biomarkers. 7:123-132
BACKGROUND Patients with colorectal cancer often present with advanced disease and concomitant poor prognosis. The best known serum biomarker, carcinoembryonic antigen (CEA) is not recommended for screening because of its limited specificity and sens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2838a6f510c31458b9c82635f3f42c7b
https://doi.org/10.3233/cbm-2010-0155
https://doi.org/10.3233/cbm-2010-0155
Autor:
Simon C. Afford, Barney Stephenson, David H. Adams, Douglas G. Ward, Ashley Martin, Neil J. Shimwell, E Humphreys
Publikováno v:
Lancet (London, England). 385
Background Cholangiocarcinoma has a high mortality and morbidity. Median survival is less than 6 months. Surgical resection is appropriate in certain circumstances. Because distal cholangiocarcinoma is difficult to distinguish from pancreatic cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2db29d0a85d0a92dc10e98474caf367
https://pubmed.ncbi.nlm.nih.gov/26312917
https://pubmed.ncbi.nlm.nih.gov/26312917
Autor:
Sarah Pirrie, Wenbin Wei, Douglas G. Ward, Maurice P. Zeegers, Richard T. Bryan, K.K. Cheng, Neil J. Shimwell, Nicholas D. James, Ashley Martin, Adam J. Devall
Publikováno v:
British Journal of Cancer, 110(3), 679-685. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer
Background:Epithelial cell adhesion molecule is overexpressed in bladder tumours and released from bladder cancer cells in vitro. We test the hypotheses that urinary EpCAM could act as a biomarker for primary bladder cancer detection and risk stratif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea921a3f02b4129af47a894b0ba7e33
https://cris.maastrichtuniversity.nl/en/publications/0277b813-2690-4c8e-8029-991299551f8d
https://cris.maastrichtuniversity.nl/en/publications/0277b813-2690-4c8e-8029-991299551f8d
Autor:
Caroline A. Millar, David E. James, Neil J. Shimwell, Michael J.O. Wakelam, Gwyn W. Gould, Sally Martin, Timo Meerloo, Gilles R.X. Hickson
Publikováno v:
Traffic. 1:141-151
Insulin increases the exocytosis of many soluble and membrane proteins in adipocytes. This may reflect a general effect of insulin on protein export from the trans Golgi network. To test this hypothesis, we have compared the trafficking of the secret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16a9eeb501b35f489c7447de0188d6fd
https://doi.org/10.1034/j.1600-0854.2000.010206.x
https://doi.org/10.1034/j.1600-0854.2000.010206.x
Autor:
Wei-Xia Chao, Nathalie Wong, Juan Zhang, Chun Pang, Yuanfang Ma, Ming Wang, Wenbin Wei, Qiang Lou, Neil J. Shimwell, Qi-Ming Wang, Philip J. Johnson, Ashley Martin, Jin Ma, Yijun Qi, Douglas G. Ward
Publikováno v:
Proteomics. 14(2-3)
The aim of this study was to identify novel biomarkers for the diagnosis of, and potential therapeutic targets for, hepatocellular carcinoma (HCC). Multilectin affinity chromatography was used to enrich N-linked glycoproteins from nontumorous liver a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849c89036772cea7168b261fb3a09d0b
https://pubmed.ncbi.nlm.nih.gov/24259486
https://pubmed.ncbi.nlm.nih.gov/24259486
Autor:
Philip J. Johnson, Douglas G. Ward, Neil J. Shimwell, Richard T. Bryan, Wenbin Wei, Maurice P. Zeegers, Ashley Martin, K K Cheng, Nicholas D. James
Publikováno v:
British Journal of Cancer
British Journal of Cancer, 108(9), 1854-1861. Nature Publishing Group
British Journal of Cancer, 108(9), 1854-1861. Nature Publishing Group
Background:\ud Proteomic discovery of cancer biomarkers in body fluids is challenging because of their low abundance in a complex\ud background. Altered gene expression in tumours may not reflect protein levels in body fluids. We have tested combinin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac221ce18f45cb9720e1a7eb56668997
Autor:
Andrew S. Turnell, Roger J.A. Grand, Grant S. Stewart, Ashley Martin, Kelly Townsend, Neil J. Shimwell, Garry G. Sedgwick, Jakob Nilsson
Publikováno v:
Oncogene
The anaphase-promoting complex/cyclosome (APC/C) is an ubiquitin ligase that functions during mitosis. Here we identify the transcriptional regulator, transcriptional intermediary factor 1γ, TIF1γ, as an APC/C-interacting protein that regulates APC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb779b4c3aa953a598ed3d0596bef2d
https://pubmed.ncbi.nlm.nih.gov/23160376
https://pubmed.ncbi.nlm.nih.gov/23160376