Zobrazeno 1 - 10
of 1 081
pro vyhledávání: '"Neil Hunter"'
Autor:
Filip Vujovic, Mary Simonian, William E. Hughes, Claire E. Shepherd, Neil Hunter, Ramin M. Farahani
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Mitochondrial activity directs neuronal differentiation dynamics during brain development. In this context, the long-established metabolic coupling of mitochondria and the eukaryotic host falls short of a satisfactory mechanistic explanation
Externí odkaz:
https://doaj.org/article/e614816f591446b3bb144eb2a89bf3bd
Autor:
Mengwen Hu, Yu-Han Yeh, Yasuhisa Munakata, Hironori Abe, Akihiko Sakashita, So Maezawa, Miguel Vidal, Haruhiko Koseki, Neil Hunter, Richard M. Schultz, Satoshi H. Namekawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
In humans, the ovarian reserve is maintained over decades by meiotic arrest of oocytes. Here the authors show that Polycomb Repressive Complex 1 (PRC1)-mediated epigenetic programming is essential for formation of ovarian reserve and thus female repr
Externí odkaz:
https://doaj.org/article/624f67717ea24811b6f89159a7977918
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Notch signalling pathway plays a key role in metazoan biology by contributing to resolution of binary decisions in the life cycle of cells during development. Outcomes such as proliferation/differentiation dichotomy are resolved by transcrip
Externí odkaz:
https://doaj.org/article/00cb7ad1cd3148079e49b2b8a14f48db
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1873 (2023)
Metazoan signalling pathways can be rewired to dampen or amplify the rate of events, such as those that occur in development and aging. Given that a linear network topology restricts the capacity to rewire signalling pathways, such scalability of the
Externí odkaz:
https://doaj.org/article/ba92bc202a4d44ce899279c37ce07555
Autor:
Sumit Sandhu, Ieng F. Sou, Jill E. Hunter, Lucy Salmon, Caroline L. Wilson, Neil D. Perkins, Neil Hunter, Owen R. Davies, Urszula L. McClurg
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Sandhu et al. report that the synaptonemal complex (SC) protein, TEX12, localises to centrosomes independently of the SC during meiosis. They also show that it provokes centrosome amplification in somatic cells, a pathology associated with cancer dev
Externí odkaz:
https://doaj.org/article/d1221d134947415086c9e1e96900d10e
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract Background Transdifferentiation describes transformation in vivo of specialized cells from one lineage into another. While there is extensive literature on forced induction of lineage reprogramming in vitro, endogenous mechanisms that govern
Externí odkaz:
https://doaj.org/article/2e223584c30e4bc5bba466bf7a3160c0
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background The origin of most of the Lactobacillus rhamnosus genome sequences lodged in NCBI can be traced to food and faecal isolates followed by blood and tissue sites but with minimal representation from oral and vaginal isolates. However
Externí odkaz:
https://doaj.org/article/6c3491d0e30c4558a21ca8b100ef02d7
Autor:
Anastasiia Bondarieva, Kavya Raveendran, Vladyslav Telychko, H. B. D. Prasada Rao, Ramya Ravindranathan, Chrysoula Zorzompokou, Friederike Finsterbusch, Ihsan Dereli, Frantzeskos Papanikos, Daniel Tränkner, Alexander Schleiffer, Ji-Feng Fei, Anna Klimova, Masaru Ito, Dhananjaya S. Kulkarni, Ingo Roeder, Neil Hunter, Attila Tóth
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Crossing over is a critical process during meiosis, although the regulation of this process still remains somewhat elusive. Here, the authors show that PRR19 partners with CNTD1 to enable formation of crossover-specific recombination complexes in mou
Externí odkaz:
https://doaj.org/article/380ea6fcb06a43c3808405a22b032e52
Autor:
Cathryn E. Birch, Benjamin L. Rabb, Steven J. Böing, Kay L. Shelton, Rob Lamb, Neil Hunter, Mark A. Trigg, Adrian Hines, Andrea L. Taylor, Charlie Pilling, Murray Dale
Publikováno v:
Journal of Flood Risk Management, Vol 14, Iss 2, Pp n/a-n/a (2021)
Abstract The risk of surface water flooding (SWF) in England is already high and its frequency and severity is projected to increase in the future. SWF generally occurs due to intense, highly localised rainfall, which is challenging to forecast with
Externí odkaz:
https://doaj.org/article/d007d5ab324249dbb69a00d02fb3b713
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Notch signalling pathway is central to development of metazoans. The pathway codes a binary fate switch. Upon activation, downstream signals contribute to resolution of fate dichotomies such as proliferation/differentiation or sub-lineage di
Externí odkaz:
https://doaj.org/article/d29815c77a71488f8c16c7bcb4426622