Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

Autor: T.G.M. van Erp, Martin Alda, Harald Kugel, Salvador Sarró, Eduard Vieta, Lucija Abramovic, Jair C. Soares, Theodore D. Satterthwaite, Sarah Trost, René S. Kahn, M F Ponteduro, Michael Bauer, M. Fatjó-Vilas, Rhoshel K. Lenroot, Amy C. Bilderbeck, Christopher R.K. Ching, Janusz K. Rybakowski, Danai Dima, Volker Arolt, Udo Dannlowski, Thomas Nickson, Henricus G. Ruhé, Christian Simhandl, Guy M. Goodwin, Edith Pomarol-Clotet, Chantal Henry, Saskia P. Hagenaars, Neil Horn, Benson Mwangi, M Bonnin, Matthew J. Kempton, Erlend Bøen, Daniel H. Wolf, Christoph Abé, Ingrid Agartz, Wayne C. Drevets, Marcus V. Zanetti, Bernhard T. Baune, Mary L. Phillips, Amelia Versace, Fabiano G. Nery, Nhat Trung Doan, Carrie E. Bearden, Fleur M. Howells, Derrek P. Hibar, Nefize Yalin, Oliver Gruber, Lars T. Westlye, Henk Temmingh, Janice M. Fullerton, Jose Manuel Goikolea, David C. Glahn, Godfrey D. Pearlson, Roel A. Ophoff, Josselin Houenou, C J Ekman, Anne Uhlmann, Rodrigo Machado-Vieira, Adrian J. Lloyd, Nelson B. Freimer, Andrew M. McIntosh, Lisa Rauer, Neda Jahanshad, Aart H. Schene, Cecilie B. Hartberg, Allison C. Nugent, Tomas Hajek, Bernd Kramer, Esther Jiménez, P. G. P. Rosa, Emma Sprooten, G. Delvecchio, Khallil T. Chaim, Allan H. Young, Silvia Alonso-Lana, Maria M. Rive, Paul M. Thompson, Erick J. Canales-Rodríguez, Maristela S. Schaufelberger, Nailin Yao, Mikael Landén, Wagner F. Gattaz, Heather C. Whalley, Torbjørn Elvsåshagen, Scott C. Fears, Beny Lafer, Dan J. Stein, Jonathan Savitz, L M Beard, Maria Concepcion Garcia Otaduy, Sophia Frangou, Dominik Grotegerd, Ulrik Fredrik Malt, Marco P. Boks, C Bourne, Ronny Redlich, J Starke, Anders M. Dale, Geraldo F. Busatto, Andrea Pfennig, Martin Ingvar, Peter R. Schofield, Dara M. Cannon, Carlos A. Zarate, Tiffany M. Chaim-Avancini, Fábio L.S. Duran, Dick J. Veltman, Bronwyn Overs, Unn K. Haukvik, Philip B. Mitchell, Márcio Gerhardt Soeiro-de-Souza, Colm McDonald, Maria Keil, Jorge R. C. Almeida, Timothy B. Meier, Joshua W. Cheung, Gloria Roberts, Xavier Caseras, Won Hee Lee, N.E.M. van Haren, Ole A. Andreassen, Pablo Najt, Natalia Lawrence

Publikováno v: Hibar, D P, Westlye, L T, Doan, N T, Jahanshad, N, Cheung, J W, Ching, C R K, Versace, A, Bilderbeck, A C, Uhlmann, A, Mwangi, B, Krämer, B, Overs, B, Hartberg, C B, Abe, C, Dima, D, Grotegerd, D, Sprooten, E, Ben, E, Jimenez, E, Howells, F M, Delvecchio, G, Temmingh, H, Starke, J, Almeida, J R C, Goikolea, J M, Houenou, J, Beard, L M, Rauer, L, Abramovic, L, Bonnin, M, Ponteduro, M F, Keil, M, Rive, M M, Yao, N, Yalin, N, Najt, P, Rosa, P G, Redlich, R, Trost, S, Hagenaars, S, Fears, S C, Alonso-Lana, S, Van Erp, T G M, Nickson, T, Chaim-Avancini, T M, Meier, T B, Elvsashagen, T, Haukvik, U K, Lee, W H, Schene, A H, Lloyd, A J, Young, A H, Nugent, A, Dale, A M, Pfennig, A, McIntosh, A M, Lafer, B, Baune, B T, Ekman, C J, Zarate, C A, Bearden, C E, Henry, C, Simhandl, C, McDonald, C, Bourne, C, Stein, D J, Wolf, D H, Cannon, D M, Glahn, D C, Veltman, D J, Pomarol-Clotet, E, Vieta, E, Canales-Rodriguez, E J, Nery, F G, Duran, F L S, Busatto, G F, Roberts, G, Pearlson, G D, Goodwin, G M, Kugel, H, Whalley, H C, Ruhe, H G, Soares, J C, Fullerton, J M, Rybakowski, J K, Savitz, J, Chaim, K T, Fatjó-Vilas, M, Soeiro-De-Souza, M G, Boks, M P, Zanetti, M V, Otaduy, M C G, Schaufelberger, M S, Alda, M, Ingvar, M, Phillips, M L, Kempton, M J, Bauer, M, Landén, M, Lawrence, N S, Van Haren, N E M, Horn, N R, Freimer, N B, Gruber, O, Schofield, P R, Mitchell, P B, Kahn, R S, Lenroot, R, Machado-Vieira, R, Ophoff, R A, Sarró, S, Frangou, S, Satterthwaite, T D, Hajek, T, Dannlowski, U, Malt, U F, Arolt, V, Gattaz, W F, Drevets, W C, Caseras, X, Agartz, I, Thompson, P M & Andreassen, O A 2018, ' Cortical abnormalities in bipolar disorder : An MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group ', Molecular Psychiatry, vol. 23, no. 4, pp. 932-942 . https://doi.org/10.1038/mp.2017.73
Molecular Psychiatry, 23(4), 932-942. Nature Publishing Group
Molecular Psychiatry
Andreassen, O A, Hibar, D P, Westlye, L T, Doan, N T, Jahanshad, N, Cheung, J, Ching, C R K, Versace, A, Bilderbeck, A, Uhlmann, A, Mwangi, B, Krämer, B, Overs, B, Hartberg, C B, Abe, C, Dima, D, Grotegerd, D, Sprooten, E, Boen, E, Jiménez, E, Howells, F M, Delvecchio, G, Temmingh, H, Starke, J, Almeida, J, Goikolea, J M, Houenou, J, Beard, L, Rauer, L, Abramovic, L, Bonnin, C, Ponteduro, M, Keil, M, Rive, M, Yao, N, Yalin, N, Najt, P, Rosa, P, Redlich, R, Trost, S, Hagenaars, S, Fears, S, Alonso-Lana, S, van Erp, T G M, Nickson, T, Chaim-Avancini, T, Meier, T, Elvsashagen, T, Haukvik, U K, Lee, W, Schene, A, Lloyd, A J, Young, A, Nugent, A C, Dale, A M, Pfennig, A, McIntosh, A, Lafer, B, Baune, B T, Ekman, C J, Zarate, C A, Bearden, C E, Henry, C, Simhandl, C, McDonald, C, Bourne, C, Stein, D, Wolf, D, Cannon, D M, Glahn, D C, Veltman, D J, Pomarol-Clotet, E, Vieta, E, Canales-Rodríguez, E, Nery, F, Duran, F, Busatto, G, Roberts, G, Pearlson, G D, Goodwin, G M, Kugel, H, Sibley, H, Ruhe, H, Soares, J C, Fullerton, J, Rybakowski, J, Savitz, J, Chaim, K, Fatjo-Vilas, M, Soeiro-de-Souza, M, Boks, M P, Zanetti, M, Otaduy, M, Schaufelberger, M, Alda, M, Ingvar, M, Phillips, M L, Kempton, M J, Bauer, M, Landén, M, Lawrence, N S, Van Haren, N E M, Horn, N, Freimer, N B, Gruber, O, Schofield, P M, Mitchell, P, Kahn, R S, Lenroot, R, Machado-Vieira, R, Ophoff, R A, Sarró, S, Frangou, S, Satterthwaite, T, Hajek, T, Dannlowski, U, Malt, U F, Arolt, V, Gattaz, W, Drevets, W C, Caseras, X, Agartz, I & Thompson, P 2017, ' Cortical abnormalities in bipolar disorder: An MRI analysis of 6,503 individuals from the ENIGMA-Bipolar Disorder Working Group ', Molecular Psychiatry . https://doi.org/10.1038/mp.2017.73
Molecular Psychiatry, 23, 932-942
Hibar, D P, Westlye, L T, Doan, N T, Jahanshad, N, Cheung, J W, Ching, C R K, Versace, A, Bilderbeck, A C, Uhlmann, A, Mwangi, B, Krämer, B, Overs, B, Hartberg, C B, Abé, C, Dima, D, Grotegerd, D, Sprooten, E, Bøen, E, Jimenez, E, Howells, F M, Delvecchio, G, Temmingh, H, Starke, J, Almeida, J R C, Goikolea, J M, Houenou, J, Beard, L M, Rauer, L, Abramovic, L, Bonnin, M, Ponteduro, M F, Keil, M, Rive, M M, Yao, N, Yalin, N, Najt, P, Rosa, P G, Redlich, R, Trost, S, Hagenaars, S, Fears, S C, Alonso-Lana, S, van Erp, T G M, Nickson, T, Chaim-Avancini, T M, Meier, T B, Elvsåshagen, T, Haukvik, U K, Lee, W H, Schene, A H, Lloyd, A J, Young, A H, Nugent, A, Dale, A M, Pfennig, A, McIntosh, A M, Lafer, B, Baune, B T, Ekman, C J, Zarate, C A, Bearden, C E, Henry, C, Simhandl, C, McDonald, C, Bourne, C, Stein, D J, Wolf, D H, Cannon, D M, Glahn, D C, Veltman, D J, Pomarol-Clotet, E, Vieta, E, Canales-Rodriguez, E J, Nery, F G, Duran, F L S, Busatto, G F, Roberts, G, Pearlson, G D, Goodwin, G M, Kugel, H, Whalley, H C, Ruhe, H G, Soares, J C, Fullerton, J M, Rybakowski, J K, Savitz, J, Chaim, K T, Fatjó-Vilas, M, Soeiro-de-Souza, M G, Boks, M P, Zanetti, M V, Otaduy, M C G, Schaufelberger, M S, Alda, M, Ingvar, M, Phillips, M L, Kempton, M J, Bauer, M, Landén, M, Lawrence, N S, van Haren, N E M, Horn, N R, Freimer, N B, Gruber, O, Schofield, P R, Mitchell, P B, Kahn, R S, Lenroot, R, Machado-Vieira, R, Ophoff, R A, Sarró, S, Frangou, S, Satterthwaite, T D, Hajek, T, Dannlowski, U, Malt, U F, Arolt, V, Gattaz, W F, Drevets, W C, Caseras, X, Agartz, I, Thompson, P M & Andreassen, O A 2018, ' Cortical abnormalities in bipolar disorder : an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group ', Molecular Psychiatry, vol. 23, no. 4, pp. 932–942 . https://doi.org/10.1038/mp.2017.73
Molecular psychiatry, 23. Nature Publishing Group
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Universidade de São Paulo (USP)
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Molecular Psychiatry, 23, 4, pp. 932-942

Contains fulltext : 191289.pdf (Publisher’s version ) (Open Access) Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well understood. Structural brain differences have been associated with BD, but results from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e38a16e91d56f2374951f6cd78cae66
https://doi.org/10.1038/mp.2017.73

Increased thalamic phospholipid concentration evident in bipolar I disorder

Autor: Dan J. Stein, Neil Horn, Fleur M. Howells, Victoria L. Ives-Deliperi

Publikováno v: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 41:1-5

Background Bipolar disorder is characterised by changes in brain metabolites, as measured by 1 H-MRS. However, there is no consistent metabolic profile for bipolar disorder, which includes changes in N-acetyl-aspartate (NAA), choline metabolites and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c4f3e273966ffc587d7375671c2eb9
https://doi.org/10.1016/j.pnpbp.2012.10.026

Staff experience of a Canadian long-term care home during a COVID-19 outbreak: a qualitative study

Autor: Lillian Hung, Sophie C. Yang, Ellen Guo, Mariko Sakamoto, Jim Mann, Sheila Dunn, Neil Horne

Publikováno v: BMC Nursing, Vol 21, Iss 1, Pp 1-9 (2022)

Abstract Background COVID-19 has significant impact on long-term care (LTC) residents and staff. The purpose of this paper is to report the data gathered during a COVID-19 outbreak in a Canadian LTC home regarding staff experiences, challenges, and n

Externí odkaz: https://doaj.org/article/8b1ecfef3b914e25b02c992da855c441

Bipolar disorder: emotional dysregulation and neuronal vulnerability

Autor: Neil Horn, Jonathan Savitz, Rajkumar Ramesar, Dan J. Stein

Publikováno v: CNS spectrums. 14(3)

Bipolar disorder is clinically characterized by fluctuating affect, and neuropsychologically by impairment in executive functions. Such phenomena are consistent with the centrality of emotional dysregulation and impulsivity to bipolar disorder. They

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd181538d7e54b60890e13b17c709a82
https://pubmed.ncbi.nlm.nih.gov/19407708

The benefits of and barriers to using a social robot PARO in care settings: a scoping review

Autor: Lillian Hung, Cindy Liu, Evan Woldum, Andy Au-Yeung, Annette Berndt, Christine Wallsworth, Neil Horne, Mario Gregorio, Jim Mann, Habib Chaudhury

Publikováno v: BMC Geriatrics, Vol 19, Iss 1, Pp 1-10 (2019)

Abstract Background Given the complexity of providing dementia care in hospitals, integrating technology into practice is a high challenge and an important opportunity. Although there are a growing demand and interest in using social robots in a vari

Externí odkaz: https://doaj.org/article/9254762c504341b3a9bb21c2efee257b