Výsledky vyhledávání - "Neil Hershey"

Structure-Function Assessment and High-Throughput Quantification of Site-Specific Aspartate Isomerization in Monoclonal Antibody Using a Novel Analytical Tool Kit

Autor: Tapan K. Das, Zhi Chen, Neil Hershey, Ming Zeng, Li Tao, James Bautista, Richard Ludwig, Xiang Cao, Kaimeng Zhou

Publikováno v: Journal of pharmaceutical sciences. 109(1)

Isomerization of surface-exposed aspartic acid (Asp) in the complementarity-determining regions of therapeutic proteins could potentially impact their target binding affinity because of the sensitive location, and often requires complex analytical ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7247867ac649d597c0777e7c46a47e7
https://pubmed.ncbi.nlm.nih.gov/31469998

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