Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Neil G. Carmichael"'
Autor:
Neil G. Carmichael, Richard Billington
Publikováno v:
Food Additives and Contaminants. 17:621-626
Reference doses (RfD) for the definition of tolerable food residues have traditionally been based on the lowest no observed adverse effect level (NOAEL), which usually comes from chronic toxicity studies. While this is generally agreed to be a safe a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5787215faf83a02db84bd8b9b4bda071
https://doi.org/10.1080/026520300412546
https://doi.org/10.1080/026520300412546
Publikováno v:
Environmental Health Perspectives
Heterozygous p53 knockout mice were investigated as a potential model for vascular tumor carcinogenesis. Groups of 20 male mice were exposed by gavage for 6 months to the vascular carcinogen urethane at 1, 10, or 100 mg/kg body weight/day. Wild-type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602086dbb6985b38bde3997d7269bc69
https://doi.org/10.1289/ehp.0010861
https://doi.org/10.1289/ehp.0010861
Publikováno v:
Environmental Health Perspectives
A survey was performed on the results of 138 carcinogenicity studies conducted in various mouse strains by the agrochemical industry over the period 1983-1993. Data for liver tumor incidence, liver weight, and histopathology were collected along with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff5b33f930708015430d7f019b67740
https://doi.org/10.1289/ehp.971051196
https://doi.org/10.1289/ehp.971051196
Publikováno v:
Toxicology and Applied Pharmacology. 141:35-43
Oxadiazon [5-ter-butyl-3-(2,4-dichloro-5-isopropoxyphenyl)-1,3,4-oxadiazol-2(3H)-one] was administered orally at 20–500 mg/kg body wt/day to male Sprague-Dawley CD rats for 14 days, at 20–200 mg/kg body wt/day to male CD1 [CR1/CD-1(1GR)BR] mice f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::265912d3904f712458cabd4367a396c8
https://doi.org/10.1016/s0041-008x(96)80006-8
https://doi.org/10.1016/s0041-008x(96)80006-8
Publikováno v:
Journal of Clinical Epidemiology, 64(5), 481-486. Elsevier Science
Objective To evaluate the need for the creation of a system in which observational epidemiology studies are registered; an Observational Studies Register (OSR). Study Design and Setting The current scientific process for observational epidemiology st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09042f08f397964f8aaec8472d2d7c62
https://cris.maastrichtuniversity.nl/en/publications/e71729f6-746e-4116-8aa1-9160342c1e24
https://cris.maastrichtuniversity.nl/en/publications/e71729f6-746e-4116-8aa1-9160342c1e24
Autor:
John E. Doe, Neil G. Carmichael, Carolyn Vickers, Melanie Bausen, Alan R. Boobis, Samuel M. Cohen, Michelle R. Embry, Richard Lewis, Claudia Fruijtier-Pölloth, Howard R. Mellor, Helmut Greim, M. E. Meek
Publikováno v:
Critical reviews in toxicology. 41(3)
The European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC), the International Life Sciences Institute (ILSI) Research Foundation (RF), and the ILSI Health and Environmental Sciences Institute (HESI) hosted a workshop in November 2009
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3524607bb2b96e49476ff3b62eaa631e
https://pubmed.ncbi.nlm.nih.gov/21401325
https://pubmed.ncbi.nlm.nih.gov/21401325
Autor:
Hugh A. Barton, Ralph L. Cooper, Vicki L. Dellarco, Penelope A. Fenner-Crisp, James C. Lamb, John E. Doe, Alan R. Boobis, Nancy G. Doerrer, Neil G. Carmichael, Timothy P. Pastoor
Publikováno v:
Critical reviews in toxicology. 36(1)
Better understanding of toxicological mechanisms, enhanced testing capabilities, and demands for more sophisticated data for safety and health risk assessment have generated international interest in improving the current testing paradigm for agricul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61043858fabca6bb22eaad9567cf13d4
https://pubmed.ncbi.nlm.nih.gov/16708692
https://pubmed.ncbi.nlm.nih.gov/16708692
Autor:
Neil G, Carmichael
Publikováno v:
Scandinavian journal of work, environmenthealth. 31
Most agrochemicals have physicochemical properties that make it impractical to apply them directly to crops and other targets. It is necessary to provide a concentrate of the active ingredient, to which formulation agents have been added to allow dil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::417173eb33e1bf120dcdf7e93d499d27
https://pubmed.ncbi.nlm.nih.gov/16190162
https://pubmed.ncbi.nlm.nih.gov/16190162
Autor:
Neil G. Carmichael
Publikováno v:
The Annals of occupational hygiene. 45
The toxicology studies required for the registration of a pesticide are not necessarily well adapted to user safety assessment. This problem can be overcome in some cases by improving the guideline studies. In other cases the guidelines are based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a411b14ada7c81186b52403ed504047
https://pubmed.ncbi.nlm.nih.gov/11290343
https://pubmed.ncbi.nlm.nih.gov/11290343
Autor:
Dominique Lassere, Neil G. Carmichael, Laurence Nicod, Lysiane Richert, Catherine Viollon-Abadie, Eric L. M. Debruyne
Publikováno v:
Toxicology and Applied Pharmacology
Toxicology and Applied Pharmacology, Elsevier, 1999, 155 (1), pp.1-12. ⟨10.1006/taap.1998.8558⟩
Toxicology and Applied Pharmacology, Elsevier, 1999, 155 (1), pp.1-12. ⟨10.1006/taap.1998.8558⟩
International audience; The effects of representative liver enzyme inducers such as clofibrate (CLO), phenobarbital (PB), pregnenolone-16alpha-carbonitrile (PCN), and beta-naphthoflavone (NF) on hepatic microsomal thyroxin (T4)- UDP-glucuronosyl tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5fed447d13ea4648e9d336e7895ee5
https://hal.archives-ouvertes.fr/hal-00502778
https://hal.archives-ouvertes.fr/hal-00502778