Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Neil G Greene"'
Publikováno v:
PLoS Pathogens, Vol 11, Iss 6, p e1004996 (2015)
Streptococcus pneumoniae (the pneumococcus) colonizes the human nasopharynx and is a significant pathogen worldwide. Pneumolysin (Ply) is a multi-functional, extracellular virulence factor produced by this organism that is critical for pathogenesis.
Externí odkaz:
https://doaj.org/article/73f3091ddf244f008abbcc0cba6d3213
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Class A penicillin-binding proteins (aPBPs) assemble the bacterial cell wall and are the targets of penicillin and related β-lactam antibiotics. In gram-negative bacteria, the aPBPs require outer membrane lipoproteins to function. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbeb10c7e913fd3d509de2a4bffc71b4
https://doi.org/10.1073/pnas.2108894118
https://doi.org/10.1073/pnas.2108894118
Penicillin-binding proteins (PBPs) are synthases required to build the essential peptidoglycan (PG) cell wall surrounding most bacterial cells. The mechanisms regulating the activity of these enzymes to control PG synthesis remain surprisingly poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4403d07ba73013585d39a981d902e2fe
https://europepmc.org/articles/PMC5866570/
https://europepmc.org/articles/PMC5866570/
Autor:
Scott Howell, George R. Dubyak, Neil G. Greene, Hesham A. Malak, Eric Pearlman, Andrew Camilli, Amy G. Hise, Aras Kadioglu, Michael A. Katsnelson, Mausita Karmakar
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), vol 194, iss 4
Although neutrophils are the most abundant cells in acute infection and inflammation, relatively little attention has been paid to their role in inflammasome formation and IL-1β processing. In the present study, we investigated the mechanism by whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aaf6e4d7287463ecec6ea3e41f17bcf
https://doi.org/10.4049/jimmunol.1401624
https://doi.org/10.4049/jimmunol.1401624
Publikováno v:
Journal of Virology. 86:8171-8184
Herpes simplex virus type 1 (HSV-1) enters cells by fusion of its envelope with a host cell membrane, which requires four viral glycoproteins and a cellular receptor. Viral fusion glycoprotein B (gB) mediates membrane fusion through the action of its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a87f60b8f632111b9fb2edd6169e97b
https://doi.org/10.1128/jvi.00932-12
https://doi.org/10.1128/jvi.00932-12
Streptococcus pneumoniae is a major causative agent of otitis media, pneumonia, bacteremia, and meningitis. Pneumolysin (Ply), a member of the cholesterol-dependent cytolysins (CDCs), is produced by virtually all clinical isolates of S. pneumoniae ,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3990cf2170324823ffe5336f608e070
https://europepmc.org/articles/PMC3393478/
https://europepmc.org/articles/PMC3393478/