Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Neil G, Stoker"'
Autor:
Adam A. Witney, Anna L. E. Bateson, Amina Jindani, Patrick P. J. Phillips, David Coleman, Neil G. Stoker, Philip D. Butcher, Timothy D. McHugh, RIFAQUIN Study Team
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-13 (2017)
Abstract Background RIFAQUIN was a tuberculosis chemotherapy trial in southern Africa including regimens with high-dose rifapentine with moxifloxacin. Here, the application of whole-genome sequencing (WGS) is evaluated within RIFAQUIN for identifying
Externí odkaz:
https://doaj.org/article/8b485d5bfae443b0bac7ebba395890d0
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials
Annals of Clinical Microbiology and Antimicrobials, Vol 19, Iss 1, Pp 1-6 (2020)
Annals of clinical microbiology and antimicrobials
Annals of Clinical Microbiology and Antimicrobials, Vol 19, Iss 1, Pp 1-6 (2020)
Annals of clinical microbiology and antimicrobials
The COVID-19 pandemic has currently overtaken every other health issue throughout the world. There are numerous ways in which this will impact existing public health issues. Here we reflect on the interactions between COVID-19 and tuberculosis (TB),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feae24ecd768ae9245c67c048b2dd3fd
https://doi.org/10.1186/s12941-020-00363-1
https://doi.org/10.1186/s12941-020-00363-1
Autor:
Ludovic Tailleux, Simon J Waddell, Mattia Pelizzola, Alessandra Mortellaro, Michael Withers, Antoine Tanne, Paola Ricciardi Castagnoli, Brigitte Gicquel, Neil G Stoker, Philip D Butcher, Maria Foti, Olivier Neyrolles
Publikováno v:
PLoS ONE, Vol 3, Iss 1, p e1403 (2008)
Transcriptional profiling using microarrays provides a unique opportunity to decipher host pathogen cross-talk on the global level. Here, for the first time, we have been able to investigate gene expression changes in both Mycobacterium tuberculosis,
Externí odkaz:
https://doaj.org/article/65e48e15cfcc4b5bad153688fefb88e7
Autor:
Marc Lipman, Molebogeng X Rangaka, Katharina Kranzer, Neil G. Stoker, Timothy D. McHugh, C. Finn McQuaid, Mishal S Khan, Ibrahim Abubakar, Chandrasekaran Padmapriyadarsini
Publikováno v:
The Indian Journal of Medical Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c89219b52b463e5d1eab2f418cd8d310
https://doi.org/10.4103/ijmr.ijmr_326_21
https://doi.org/10.4103/ijmr.ijmr_326_21
Drug-resistant tuberculosis has become a major public health problem. Resistance to rifampicin probably arises through mutations in the mycobacterial RNA polymerase. Patients may acquire rifampicin resistant tuberculosis by three mechanisms: (1) infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e880a6125908f6d4816825bc6c98cc
https://doi.org/10.1016/0962-8479(93)90049-4
https://doi.org/10.1016/0962-8479(93)90049-4
Autor:
Adam A. Witney, Philip D. Butcher, Neil G. Stoker, Amber Arnold, Jason Hinds, Catherine Cosgrove
Publikováno v:
BMC Medicine
Drug-resistant tuberculosis (TB) remains a major challenge to global health and to healthcare in the UK. In 2014, a total of 6,520 cases of TB were recorded in England, of which 1.4 % were multidrug-resistant TB (MDR-TB). Extensively drug-resistant T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724ce832c7e007a853882d83a50612ba
https://doi.org/10.1186/s12916-016-0598-2
https://doi.org/10.1186/s12916-016-0598-2
Autor:
Jérôme Nigou, Claudia Nobrega, Germain Puzo, Sílvia Vale-Costa, Simon O. Clark, Roy Ummels, Ann Williams, A. Afonso-Barroso, Farahnaz Movahedzadeh, Arjen Sloots, P. van der Ley, Jeroen Geurtsen, G.T. Rosa, Rui Appelberg, Sandro Silva-Gomes, B.J. Appelmelk, Neil G. Stoker, Marlène Cot
Publikováno v:
Cellular Microbiology. 15:660-674
Mannose-capped lipoarabinomannan (ManLAM) is considered an important virulence factor of Mycobacterium tuberculosis. However, while mannose caps have been reported to be responsible for various immunosuppressive activities of ManLAM observed in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f30e03f5c8590ff263502121f1d3ffe4
https://doi.org/10.1111/cmi.12065
https://doi.org/10.1111/cmi.12065
Publikováno v:
Environmental Microbiology Reports. 4:168-182
Summary The metabolism of cholesterol in Mycobacterium smegmatis mc2155 has been investigated by using a microarray approach. The transcriptome of M. smegmatis growing in cholesterol was compared with that of cells growing in glycerol as the sole car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a2a02cbccf0da6b9a8df91542bfa6c5
https://doi.org/10.1111/j.1758-2229.2011.00314.x
https://doi.org/10.1111/j.1758-2229.2011.00314.x
Autor:
Annemieke Ten Bokum, Iria Uhia-Castro, Mike Withers, Ricardo Balhana, Sharon L. Kendall, Chen Gao, Neil G. Stoker, Philippa Burgess, J. Shaun Lott
Publikováno v:
Microbiology
Mycobacterium tuberculosis is able to use a variety of carbon sources in vivo and current knowledge suggests that cholesterol is used as a carbon source during infection. The catabolized cholesterol is used both as an energy source (ATP generation) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35396471ca7f5c7f3a610fc42b68780f
https://doi.org/10.1099/mic.0.034538-0
https://doi.org/10.1099/mic.0.034538-0
Autor:
Digby F. Warner, Nackmoon Sung, Liana Tsenova, Neil G. Stoker, James C. Sacchettini, Valerie Mizrahi, Gilla Kaplan, Bavesh D. Kana, Bhavna G. Gordhan, Edith E. Machowski, Garth L. Abrahams
Publikováno v:
Journal of Bacteriology. 192:2220-2227
The environment encountered by Mycobacterium tuberculosis during infection is genotoxic. Most bacteria tolerate DNA damage by engaging specialized DNA polymerases that catalyze translesion synthesis (TLS) across sites of damage. M. tuberculosis posse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113996d57332c95f3209b6ae86d62818
https://doi.org/10.1128/jb.01135-09
https://doi.org/10.1128/jb.01135-09