Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Neil E. Garrett"'
Publikováno v:
British Journal of Pharmacology. 124:1573-1579
1 Neurogenic vasoactive responses in rat skin were investigated following 8 weeks of streptozotocin-induced diabetes to determine the effect of diabetes and of treatment with insulin and nerve growth factor (NGF) treatment. 2 Diabetic rats were divid
Publikováno v:
The Journal of Neuroscience. 17:8459-8467
Acute superfusion of nerve growth factor (NGF; 1–100 ng/ml) through a naive rat spinal cord preparation did not alter basal or electrically evoked release of substance P-like immunoreactivity (SP-LI). In contrast, neurotrophin-3 (NT-3; 1–100 ng/m
Publikováno v:
Molecular Brain Research. 42:272-278
Given the involvement of the sensory nervous system in the aetiology of neurogenic inflammation, we have investigated the effect of experimental diabetes and any associated sensory nerve dysfunction on the development of complete Freund's adjuvant-in
Publikováno v:
Environmental Health Perspectives
A graphic approach termed a Genetic Activity Profile (GAP) has been developed to display a matrix of data on the genetic and related effects of selected chemical agents. The profiles provide a visual overview of the quantitative (doses) and qualitati
Publikováno v:
Neuroscience Letters. 193:205-207
The relatively few studies that have investigated the effects of the nervous system on chronic joint disease have reported conflicting results. We have reassessed the effects of capsaicin on experimental polyarthritis with particular reference to the
Publikováno v:
Neuroscience letters. 230(1)
We have investigated the effect of capsaicin pretreatment (50 mg kg −1 s.c.) on substance P, preprotachykinin (PPT) mRNA, and nerve growth factor (NGF), plus its high-affinity receptor, trkA, in adult rats with adjuvant arthritis. Twenty one days a
Publikováno v:
Neuroscience letters. 222(3)
This study compared the effects of treatment of diabetic rats with either alpha-lipoic acid (100 mg/kg/day i.p. 5 days/week) or with recombinant human nerve growth factor (rhNGF; 0.2 mg/kg s.c. 3 days/week) on NGF-like immunoreactivity (NGFLI) and ne
Autor:
Paul I. Mapp, Neil E. Garrett, David R. Blake, Bruce L. Kidd, Simon C. Cruwys, Victoria A. Jolliffe
Publikováno v:
Brain research. 688(1-2)
Many inflammatory conditions show topographically precise symmetrical responses. In this study we assessed vascular and cellular responses of apparently normal knees following induction of monoarthritis on the opposite side. A strictly localised mono
Publikováno v:
Brain research. 675(1-2)
We have measured changes in the expression of γ-preprotachykinin mRNA and levels of the neuropeptide substance P in the lumbar 4 and 5 dorsal root ganglia at various time points following the induction of an antigenic monoarthritis in the rat knee.
Publikováno v:
British journal of pharmacology. 113(3)
1. The role of bradykinin B1 and B2 receptors in bradykinin- and des-Arg9-bradykinin-induced plasma extravasation in normal and inflamed rat knee joints was investigated by use of an antigen-induced model of chronic arthritis. A modification of an Ev