Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Neil D.H. Raven"'
Autor:
Pedro Lamosa, Rita Ventura, Christopher D. Maycock, Helena Santos, Neil D.H. Raven, Marta V. Rodrigues, Luís G. Gonçalves, Jean Carr
Publikováno v:
Extremophiles. 17:137-146
The accumulation of organic solutes was investigated in the thermophilic bacteria Persephonella marina and Marinitoga piezophila, two representatives of the deepest lineages in the domain Bacteria. These organisms grow optimally at around 70 °C in m
Autor:
Neil D.H. Raven, H. Murdoch, Michael Ungurs, Toryn Poolman, Sarah J. O'Brien, J.R. Hesp, G. McLuckie, P. Wells, John Mark Sutton, J.T. Walker
Publikováno v:
Journal of Hospital Infection. 74:144-151
The stability of the infectious agent causing variant Creutzfeldt-Jakob disease (vCJD) has highlighted the importance of cleaning surgical instruments for controlling potential spread of iatrogenic CJD. In this study, thermostable adenylate kinases (
Autor:
G. McLuckie, P. Wells, L. Batten, Sarah J. O'Brien, J.R. Hesp, Toryn Poolman, C. Budge, Neil D.H. Raven, Frances Alexander, John Mark Sutton
Publikováno v:
Journal of Hospital Infection. 74:137-143
Adenylate kinase (tAK), a thermostable enzyme, was assessed as a possible means of providing a quantitative measure of cleaning efficacy suitable for validating the performance of an automated washer disinfector (AWD) during routine use. Two indicato
Publikováno v:
British Dental Journal. 203:395-401
Cleaning of dental instruments is the first line of control in reducing the adherent bioburden. The threat of vCJD and the difficulty in removing prion protein has provided a new challenge for cleaning surgical and dental instruments. Prion proteins
Publikováno v:
Biochemical and Biophysical Research Communications. 362:695-699
The interactions and conformational changes that lead to the conversion of the normal prion protein (PrP c ) to its pathogenic form, PrP sc , are still being elucidated. Using Surface Plasma Resonance (SPR), we provide evidence that a synthetic pepti
Publikováno v:
Clinical Infectious Diseases. 43:757-764
New prion-related disorders have emerged over the past 20 years, of which the most notable in the human context is variant Creutzfeldt-Jakob disease (CJD). This disorder is a challenge to medical and public health professionals seeking early detectio
Autor:
Marta V. Rodrigues, Neil D.H. Raven, Lígia O. Martins, Pedro Lamosa, Helena Santos, Luís G. Gonçalves
Publikováno v:
Applied and Environmental Microbiology. 72:6169-6173
The accumulation of compatible solutes was studied in the hyperthermophilic bacterium Aquifex pyrophilus as a function of the temperature and the NaCl concentration of the growth medium. Nuclear magnetic resonance analysis of cell extracts revealed t
Autor:
John Mark Sutton, Heather Murdoch, D. Perrett, Neil D.H. Raven, James T. Walker, Jo Dickinson, David M. Taylor
Publikováno v:
Journal of Hospital Infection. 63:432-438
Summary The issues of cross-infection and the survival of variant Creutzfeldt Jakob disease (vCJD) on surgical instruments have highlighted the importance of cleanliness of multiple-use surgical instruments. The aim of this study was to assess the le
Autor:
Neil D.H. Raven, Richard J. Sharp
Publikováno v:
FEMS Microbiology Letters. 146:135-141
The nutritional requirements of Pyrococcus furiosus were determined using extended continuous culture in the absence of elemental sulfur in an anaerobic gaslift bioreactor. Replacement of complex nutrients by maltose, amino acids and vitamins alone s
Publikováno v:
Extremophiles. 6:209-216
The protection of mannosylglycerate, at 0.5 M concentration, against heat inactivation of the model enzyme lactate dehydrogenase (LDH) was compared to that exerted by other compatible solutes, namely, trehalose, ectoine, hydroxyectoine, di- myo-inosi