Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Neil D, Theise"'
Publikováno v:
Diagnostics, Vol 14, Iss 14, p 1473 (2024)
Androgens have long been recognized as oncogenic agents. They can induce both benign and malignant hepatocellular neoplasms, including hepatocellular adenoma (HCA) and hepatocellular carcinoma, though the underlying mechanisms remain unclear. Androge
Externí odkaz:
https://doaj.org/article/6e73463f062c47ee977cdfdb8631dfcb
Autor:
Kapish Gupta, Jimmy P Xu, Tamir Diamond, Iris E M de Jong, Andrew Glass, Jessica Llewellyn, Neil D Theise, Orith Waisbourd-Zinman, Jeffrey D Winkler, Edward M Behrens, Clementina Mesaros, Rebecca G Wells
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301824 (2024)
Biliary atresia is a neonatal disease characterized by damage, inflammation, and fibrosis of the liver and bile ducts and by abnormal bile metabolism. It likely results from a prenatal environmental exposure that spares the mother and affects the fet
Externí odkaz:
https://doaj.org/article/74507efcbeca4a1daf62e83fff6e33fb
Autor:
Laura Senatus, Lander Egaña-Gorroño, Raquel López-Díez, Sonia Bergaya, Juan Francisco Aranda, Jaume Amengual, Lakshmi Arivazhagan, Michaele B. Manigrasso, Gautham Yepuri, Ramesh Nimma, Kaamashri N. Mangar, Rollanda Bernadin, Boyan Zhou, Paul F. Gugger, Huilin Li, Richard A. Friedman, Neil D. Theise, Alexander Shekhtman, Edward A. Fisher, Ravichandran Ramasamy, Ann Marie Schmidt
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-20 (2023)
Male and female mice deficient in DIAPH1 are protected from the development of experimental atherosclerosis and display reduced cholesterol levels; these changes are linked to the regulation of SREBP1 subcellular localization.
Externí odkaz:
https://doaj.org/article/3b884c6d0ad746b0ae3401514cb0c693
Autor:
Jessica Llewellyn, Caterina Fede, Abigail E. Loneker, Chet S. Friday, Michael W. Hast, Neil D. Theise, Emma E. Furth, Maria Guido, Carla Stecco, Rebecca G. Wells
Publikováno v:
JHEP Reports, Vol 5, Iss 9, Pp 100760- (2023)
Background & Aims: Glisson’s capsule is the interstitial connective tissue that surrounds the liver. As part of its normal physiology, it withstands significant daily changes in liver size. The pathophysiology of the capsule in disease is not well
Externí odkaz:
https://doaj.org/article/f72ca49d744e4847ab46882bd3e9e617
Autor:
Neel H. Mehta, Richard A. Suss, Jonathan P. Dyke, Neil D. Theise, Gloria C. Chiang, Sara Strauss, Leslie Saint-Louis, Yi Li, Silky Pahlajani, Vivek Babaria, Lidia Glodzik, Roxana O. Carare, Mony J. de Leon
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105776- (2022)
Cerebrospinal fluid (CSF), predominantly produced in the ventricles and circulating throughout the brain and spinal cord, is a key protective mechanism of the central nervous system (CNS). Physical cushioning, nutrient delivery, metabolic waste, incl
Externí odkaz:
https://doaj.org/article/0f599b471db34d7ab3b78b2b0ab98636
Clinical and Intestinal Histopathological Findings in SARS-CoV-2/COVID-19 Patients with Hematochezia
Autor:
Margaret Cho, Weiguo Liu, Sophie Balzora, Yvelisse Suarez, Deepthi Hoskoppal, Neil D. Theise, Wenqing Cao, Suparna A. Sarkar
Publikováno v:
Case Reports in Gastroenterology, Vol 15, Iss 1, Pp 408-417 (2021)
Gastrointestinal (GI) symptoms of SARS-CoV-2/COVID-19 in the form of anorexia, nausea, vomiting, abdominal pain and diarrhea are usually preceded by respiratory manifestations and are associated with a poor prognosis. Hematochezia is an uncommon clin
Externí odkaz:
https://doaj.org/article/df9b8cc317d84cfab2017c721aa162ac
Autor:
Odise Cenaj, Douglas H. R. Allison, Rami Imam, Briana Zeck, Lilly M. Drohan, Luis Chiriboga, Jessica Llewellyn, Cheng Z. Liu, Young Nyun Park, Rebecca G. Wells, Neil D. Theise
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Odise Cenaj et al. find that the fibrous interstitial spaces within and around organs may in fact be continuous networks throughout the human body. Using traceable particles injected into colon and skin interstitial spaces in human tissue samples, th
Externí odkaz:
https://doaj.org/article/92e98ad5bcd24b3a891456710da3dc47
Autor:
Joshua C. Leinwand, Bidisha Paul, Ruonan Chen, Fangxi Xu, Maria A. Sierra, Madan M. Paluru, Sumant Nanduri, Carolina G. Alcantara, Sorin A.A. Shadaloey, Fan Yang, Salma A. Adam, Qianhao Li, Michelle Bandel, Inderdeep Gakhal, Lara Appiah, Yuqi Guo, Mridula Vardhan, Zia Flaminio, Emilie R. Grodman, Ari Mermelstein, Wei Wang, Brian Diskin, Berk Aykut, Mohammad Khan, Gregor Werba, Smruti Pushalkar, Mia McKinstry, Zachary Kluger, Jaimie J. Park, Brandon Hsieh, Kristen Dancel-Manning, Feng-Xia Liang, James S. Park, Anjana Saxena, Xin Li, Neil D. Theise, Deepak Saxena, George Miller
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 8 (2022)
The gut microbiome shapes local and systemic immunity. The liver is presumed to be a protected sterile site. As such, a hepatic microbiome has not been examined. Here, we showed a liver microbiome in mice and humans that is distinct from that of the
Externí odkaz:
https://doaj.org/article/011bed70f0954f7a9e622c439b9567e1
Autor:
Savannah M. Rocha, Anna C. Fagre, Amanda S. Latham, Jason E. Cummings, Tawfik A. Aboellail, Philip Reigan, Devin A. Aldaz, Casey P. McDermott, Katriana A. Popichak, Rebekah C. Kading, Tony Schountz, Neil D. Theise, Richard A. Slayden, Ronald B. Tjalkens
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite significant research efforts, treatment options for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain limited. This is due in part to a lack of therapeutics that increase host defense to the virus. Replication of SARS-CoV-2
Externí odkaz:
https://doaj.org/article/042ff2a87d9a449d818ce9b18173369f
Autor:
Neel H. Mehta, Jonah Sherbansky, Angela R. Kamer, Roxana O. Carare, Tracy Butler, Henry Rusinek, Gloria C. Chiang, Yi Li, Sara Strauss, L. A. Saint-Louis, Neil D. Theise, Richard A. Suss, Kaj Blennow, Michael Kaplitt, Mony J. de Leon
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
The human brain functions at the center of a network of systems aimed at providing a structural and immunological layer of protection. The cerebrospinal fluid (CSF) maintains a physiological homeostasis that is of paramount importance to proper neuro
Externí odkaz:
https://doaj.org/article/66f26e66bfc045c3b1356ec2725aaaf4