Zobrazeno 1 - 10 of 99 pro vyhledávání: '"Neil D, Telling"'
1
Clot-targeted magnetic hyperthermia permeabilizes blood clots to make them more susceptible to thrombolysis
Autor: David Cabrera, Maneea Eizadi Sharifabad, Jacob A. Ranjbar, Neil D. Telling, Alan G.S. Harper
Publikováno v: Journal of thrombosis and haemostasis : JTHREFERENCES. 20(11)
BACKGROUND: Thrombolysis is a frontline treatment for stroke, which involves the application of tissue plasminogen activator (tPA) to trigger endogenous clot-degradation pathways.However, it is only effective within 4.5 hours of symptom onset due to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df088518ee9c01bd83055f009bef432f
https://pubmed.ncbi.nlm.nih.gov/35950914
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2
Akademický článek
Emerging Approaches to Investigate the Influence of Transition Metals in the Proteinopathies
Autor: Frederik Lermyte, James Everett, Jake Brooks, Francesca Bellingeri, Kharmen Billimoria, Peter J. Sadler, Peter B. O’Connor, Neil D. Telling, Joanna F. Collingwood
Publikováno v: Cells, Vol 8, Iss 10, p 1231 (2019)
Transition metals have essential roles in brain structure and function, and are associated with pathological processes in neurodegenerative disorders classed as proteinopathies. Synchrotron X-ray techniques, coupled with ultrahigh-resolution mass spe
Externí odkaz: https://doaj.org/article/6debd0ab7b2c4aa28856e8856588633c
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3
Bacterial production of vanadium ferrite spinel (Fe,V)3O4 nanoparticles
Autor: Gerrit van der Laan, James M. Byrne, Elke Arenholz, Richard A. D. Pattrick, Jonathan R. Lloyd, Neil D. Telling, Victoria S. Coker
Publikováno v: Coker, V, Van Der Laan, G, Telling, N D, Lloyd, J, Byrne, J M, Arenholz, E & Pattrick, R 2020, ' Bacterial production of vanadium ferrite spinel (Fe,V)3O4 nanoparticles ', Mineralogical Magazine, pp. 1-38 . https://doi.org/10.1180/mgm.2020.55
Biogenic nanoscale vanadium magnetite is produced by converting V(V)-bearing ferrihydrites through reductive transformation using the metal-reducing bacterium Geobacter sulfurreducens. With increasing vanadium in the ferrihydrite, the amount of V-dop
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a9e417c86de1bfb88f67be5a6c202d
https://doi.org/10.1180/mgm.2020.55
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4
Iron stored in ferritin is chemically reduced in the presence of aggregating Aβ(1-42)
Autor: Peter J. Sadler, Jon Dobson, Jake Brooks, Peter B. O’Connor, Frederik Lermyte, Neil D. Telling, Joanna F. Collingwood, James Everett
Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Atypical low-oxidation-state iron phases in Alzheimer’s disease (AD) pathology are implicated in disease pathogenesis, as they may promote elevated redox activity and convey toxicity. However, the origin of low-oxidation-state iron and the pathways
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016282e88fe429d0b0fa27410977104b
http://link.springer.com/article/10.1038/s41598-020-67117-z
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6
Metal Ion Binding to the Amyloid β Monomer Studied by Native Top-Down FTICR Mass Spectrometry
Autor: Frederik Lermyte, Peter B. O’Connor, Peter J. Sadler, Joanna F. Collingwood, Mark P. Barrow, Jake Brooks, Neil D. Telling, Yuko P. Y. Lam, Christopher A. Wootton, James Everett
Publikováno v: Journal of the American Society for Mass Spectrometry
Native top-down mass spectrometry is a fast, robust biophysical technique that can provide molecular-scale information on the interaction between proteins or peptides and ligands, including metal cations. Here we have analyzed complexes of the full-l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0fbbc18cd880730feff3dd28a3ec2c
https://doi.org/10.1007/s13361-019-02283-7
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7
Correlative Spectromicroscopy and Tomography for Biomedical Applications Involving Electron, Ion, and Soft X-ray Microscopies
Autor: Xiaoyue Wang, Neil D. Telling, Kathryn Grandfield, Joanna F. Collingwood, James Everett, Adam P. Hitchcock
Publikováno v: Microscopy Today. 27:12-19
Many important scientific and technical problems are best addressed using multiple, microscopy-based analytical techniques that combine the strengths of complementary methods. Here, we provide two examples from biomedical challenges: unravelling the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37301b66b244887be64ebebcaa5d0dd8
https://doi.org/10.1017/s1551929518001256
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8
Biogenic metallic elements in the human brain?
Autor: Kharmen Billimoria, James Everett, Xiongwei Zhu, Peter B. O’Connor, Ian Hands-Portman, Germán Plascencia-Villa, Vindy Tjendana-Tjhin, Neil D. Telling, Jake Brooks, Frederik Lermyte, George Perry, Joanna F. Collingwood, Jane M. Donnelly, Peter J. Sadler
Publikováno v: Science Advances
Discovery of nanometallic Cu0 with Fe0 in the human brain will fundamentally boost our understanding of neurobiology.
The chemistry of copper and iron plays a critical role in normal brain function. A variety of enzymes and proteins containing p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec26e6dbe13e7ed07dc07621a23e0fb6
https://eprints.keele.ac.uk/9774/1/eabf6707.full.pdf
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9
Nanoscale chemical speciation of β-amyloid/iron aggregates using soft x-ray spectromicroscopy
Autor: Neil D. Telling, James Everett, Jake Brooks, Joanna F. Collingwood
Iron (Fe) is an essential trace element required for healthy brain function. Yet, disrupted iron neurochemistry, and the associated formation of aberrantly aggregated protein lesions has been implicated in the development of multiple degenerative bra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d1a83b78ed898fe6e1bc1704ec847d
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10
Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)
Autor: José-Luis Todolí, D. Brynn Hibbert, Derek Craston, Neil D. Telling, Andreas Limbeck, Martín Resano, John M. Chalmers, Torsten Schoenberger, Joanna F. Collingwood, John Warren, Geoffrey Dent, Heidi Goenaga Infante, Adam LeGresley, Kristie Adams
Publikováno v: RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Recommendations are given concerning the terminology of concepts and methods used in spectroscopy in analytical chemistry, covering nuclear magnetic resonance spectroscopy, atomic spectroscopy, and vibrational spectroscopy. © 2021 IUPAC and De Gruyt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65bde4fbffe06ebe72a842a89c72771c
http://zaguan.unizar.es/record/118167
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