Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Neil B. Rayment"'
Autor:
Natalie J. Prescott, Liljana Petrovska, John Hermon-Taylor, Alex Boussioutas, Tim Elliott, Barry N. Hudspith, Jonathan Brostoff, Christopher G. Mathew, Neil B. Rayment, Jeremy D. Sanderson
Publikováno v:
Journal of Gastroenterology and Hepatology. 30:1265-1274
Background and Aim Escherichia coli can be isolated from lamina propria macrophages in Crohn's disease (CD), and their intramacrophage persistence may provide a stimulus for inflammation. To further determine the contributions of macrophage dysfuncti
Autor:
Jonathan Brostoff, Barry N. Hudspith, Gareth Parkes, Liljana Petrovska, Kevin Whelan, Miranda Lomer, Neil B. Rayment, Jeremy D. Sanderson
Publikováno v:
Neurogastroenterology & Motility. 24:31-39
Background There is increasing evidence to support a role for the gastrointestinal microbiota in the etiology of irritable bowel syndrome (IBS). Given the evidence of an inflammatory component to IBS, the mucosa-associated microbiota potentially play
Autor:
Christopher G. Mathew, John Hermon-Taylor, Rebecca Hands, Tim Elliott, Alex Boussioutas, Natalie J. Prescott, Stephen A. Bustin, Liljana Petrovska, Jonathan Brostoff, Kirstin M. Taylor, Gareth Parkes, Neil B. Rayment, Barry N. Hudspith, Jeremy D. Sanderson
Publikováno v:
BMC Gastroenterology
Background Abnormal handling of E. coli by lamina propria (LP) macrophages may contribute to Crohn’s disease (CD) pathogenesis. We aimed to determine LP macrophage phenotypes in CD, ulcerative colitis (UC) and healthy controls (HC), and in CD, to c
Autor:
Aravinth U. Murugananthan, P J Tozer, Neil B. Rayment, Ailsa Hart, N Daulatzai, R. K. S. Phillips, Kevin Whelan
Publikováno v:
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 17(3)
Aim The aetiology of Crohn's disease-related anal fistula remains obscure. Microbiological, genetic and immunological factors are thought to play a role but are not well understood. The microbiota within anal fistula tracts has never been examined us
Autor:
Tim Elliott, B N Hudspith, Liljana Petrovska, Michael B. Cooley, Jeremy D. Sanderson, Clifton K. Fagerquist, Robert E. Mandrell, Luke P. Randall, Alex Boussioutas, Guanghui Wu, Jonathan Brostoff, Gareth Parkes, Beatriz Quiñones, Neil B. Rayment
Publikováno v:
Inflammatory bowel diseases. 19(11)
BACKGROUND Mucosa-associated Escherichia coli are abundant in inflammatory bowel disease (IBD), but whether these bacteria gain intracellular access within the mucosa is uncertain. If E. coli does gain intracellular access, the contribution of bacter
Autor:
M Michael, G L Green, Barry N. Hudspith, Jeremy D. Sanderson, Neil B. Rayment, Jonathan Brostoff, David S. Rampton, Kenneth D. Bruce, N Staines, M Mylonaki
Publikováno v:
Journal of applied microbiology. 100(3)
Aims: To study large intestinal mucosal bacterial communities by Denaturing Gradient Gel Electrophoresis (DGGE) profiling and sequencing of 16S rRNA gene polymerase chain reaction (PCR) products amplified from DNA extracted from colorectal biopsies t
Autor:
Neil B. Rayment, Tracey Elliott, R. Linedale, Jeremy D. Sanderson, Barry N. Hudspith, John Hermon-Taylor, Tim J. Bull
Publikováno v:
Gut. 60:A142-A143
Introduction Abnormal intestinal macrophage function which could allow persistence of candidate bacterial triggering agents such as E coli and Mycobacterium avium subspecies paratuberculosis (MAP), has been implicated in the pathogenesis of Crohn9s d
* Virulence factors, antimicrobial resistance genes and protein structure of crohn's disease-derived
Autor:
Neil B. Rayment, Jonathan Brostoff, G Wu, Jeremy D. Sanderson, Liljana Petrovska, Tracey Elliott, Alex Boussioutas, Barry N. Hudspith, John Hermon-Taylor, Luke P. Randall
Publikováno v:
Gut. 60:A202-A203
Introduction Intracellular Escherichia coli isolates are found in up to 60% of gut biopsies from patients with Crohn9s disease (CD). Although adherent invasive E coli (AIEC) are described, other intracellular E coli are frequently isolated but specif
Autor:
O H Al-Hassi, T Ansari, Ailsa Hart, D Bernardo Ordiz, Stella C. Knight, Kevin Whelan, R. K. S. Phillips, A Murguranathan, P J Tozer, N Daulatzai, Neil B. Rayment
Publikováno v:
Gut. 60:A220-A221
Introduction The aetiology of perianal fistulating Crohn9s disease remains obscure but genetic, microbiological and immunological factors play a role. Dendritic cells (DC) are antigen presenting cells which sample mucosal-associated bacteria and migr
Publikováno v:
Inflammatory Bowel Diseases. 12:826-827