Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Neil A. Whittemore"'
Publikováno v:
Biomolecular NMR Assignments. 4:9-12
The aminoglycoside phosphotransferase(3')-IIIa (APH) is a promiscuous enzyme and renders a large number of structurally diverse aminoglycoside antibiotics useless against infectious bacteria. A remarkable property of this approximately 31 kDa enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07637471b1644cf5adb9cb524f5fe6f9
https://doi.org/10.1007/s12104-009-9195-z
https://doi.org/10.1007/s12104-009-9195-z
Autor:
Cynthia B. Peterson, Neil A. Whittemore, Nancy A Horn, Engin H. Serpersu, Gregory B. Hurst, Anand Mayasundari
Publikováno v:
Journal of Biological Chemistry. 279:35867-35878
The primary sequence of the N-terminal somatomedin B (SMB) domain of native vitronectin contains 44 amino acids, including a framework of four disulfide bonds formed by 8 closely spaced cysteines in sequence patterns similar to those found in the cys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64e2e779e10ca9f1de7893b3e9b9998
https://doi.org/10.1074/jbc.m405716200
https://doi.org/10.1074/jbc.m405716200
Publikováno v:
Journal of Biological Chemistry. 279:29359-29366
The three-dimensional structure of an N-terminal fragment comprising the first 51 amino acids from human plasma vitronectin, the somatomedin B (SMB) domain, has been determined by two-dimensional NMR approaches. An average structure was calculated, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bc1c01d4d35ca317cc0d7a91c59bdf2
https://doi.org/10.1074/jbc.m401279200
https://doi.org/10.1074/jbc.m401279200
Publikováno v:
Journal of Electroanalytical Chemistry. 493:28-36
The adsorption kinetics of an anthraquinone derivative bearing a two-carbon amido side chain terminated with a thiol (9,10-anthraquinone-2-carboxylic acid (2-mercaptoethyl) amide) have been examined on bare gold electrodes and on gold electrodes that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357ea5a195fe8bb6e561d826365ffcda
https://doi.org/10.1016/s0022-0728(00)00278-3
https://doi.org/10.1016/s0022-0728(00)00278-3
Autor:
P. Dan Cook, James Q. Chambers, Neil A. Whittemore, Gopal B. Inamati, Vilmos Kertesz, Muthiah Manoharan, David C. Baker
Publikováno v:
Electroanalysis. 12:889-894
Gold electrodes modified with a DNA 20-mer via a thiol linkage were shown to efficiently capture the complementary 20-mer that was tagged with anthraquinone (AQ) reporter groups. Treatment of the electrodes with 2-mercaptoethanol was required for bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19afeccf27f7efaffed3665147b57a50
https://doi.org/10.1002/1521-4109(200008)12:12<889::aid-elan889>3.0.co
https://doi.org/10.1002/1521-4109(200008)12:12<889::aid-elan889>3.0.co
Autor:
Neil A. Whittemore, Muthiah Manoharan, Mullenix An, Cook Pd, Inamati Gb, James Q. Chambers, David C. Baker, Albert A. Tuinman
Publikováno v:
Bioconjugate Chemistry. 10:261-270
Electroactive oligodeoxynucleotides (ODNs) with specific base sequences have a potential application as electrical sensors for DNA molecules. To this end, a phosphoramidite that bears a 9, 10-anthraquinone (AQ) group tethered to the 2'-O of the uridi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6810ccf17fe6063a577fa8f9600acb7
https://doi.org/10.1021/bc980095i
https://doi.org/10.1021/bc980095i
Publikováno v:
Carbohydrate Research. 310:177-189
The anthocyanins accumulated by carrot cell cultures include some that are acylated. Addition of cinnamic and benzoic acid analogues to the culture medium resulted in the production of fourteen novel monoacylated anthocyanins. Four additional anthocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1f89df750d0b12f482ac7c23e41f433
https://doi.org/10.1016/s0008-6215(98)00124-4
https://doi.org/10.1016/s0008-6215(98)00124-4
Autor:
Neil A. Whittemore, Karen T. Welch, Kristopher G. Virga, Engin H. Serpersu, Cynthia Lee Brown, Edward Wright, Richard E. Lee, Can Özen
Chemical modification and inactivation of aminoglycosides by many different enzymes expressed in pathogenic bacteria are the main mechanisms of bacterial resistance to these antibiotics. In this work, we designed inhibitors that contain the 1,3-diami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d2213b937b1836789986ed6bd712fa
https://hdl.handle.net/11511/29997
https://hdl.handle.net/11511/29997
Autor:
Ronald Wetzel, Indu Kheterpal, Rajesh P. Mishra, Engin H. Serpersu, Angela Williams, Neil A. Whittemore
Publikováno v:
Biochemistry. 44(11)
We describe here details of the hydrogen-deuterium (H/D) exchange behavior of the Alzheimer's peptide Abeta(1)(-)(40), while it is a resident in the amyloid fibril, as determined by high-resolution solution NMR. Kinetics of H/D exchange in Abeta(1)(-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a895ae2b71983536b10a5fa383fab4ac
https://pubmed.ncbi.nlm.nih.gov/15766273
https://pubmed.ncbi.nlm.nih.gov/15766273
Publikováno v:
The Journal of biological chemistry. 279(28)
The three-dimensional structure of an N-terminal fragment comprising the first 51 amino acids from human plasma vitronectin, the somatomedin B (SMB) domain, has been determined by two-dimensional NMR approaches. An average structure was calculated, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44b72ce0e0d95d123195e1ff2ba5f27f
https://pubmed.ncbi.nlm.nih.gov/15123712
https://pubmed.ncbi.nlm.nih.gov/15123712