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pro vyhledávání: '"Neil A. Rana"'
Autor:
Ajay Ashok, Suman Chaudhary, Aaron S. Wise, Neil A. Rana, Dallas McDonald, Alexander E. Kritikos, Ewald Lindner, Neena Singh
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1253 (2021)
In this report, we evaluated the role of iron in sodium iodate (NaIO3)-induced model of age-related macular degeneration (AMD) in ARPE-19 cells in-vitro, and mouse models in-vivo. ARPE-19 cells, a human retinal pigmented epithelial cell line, were ex
Externí odkaz:
https://doaj.org/article/65a4ee5dcad1402d833c5772e9de8d51
Autor:
Suman Chaudhary, Alexander E. Kritikos, Neena Singh, Clifford V. Harding, Neil A. Rana, Dallas McDonald, Aaron S. Wise, Ajay Ashok
Publikováno v:
J Alzheimers Dis
Background: Accumulation of iron is a consistent feature of Alzheimer’s disease (AD) brains. The underlying cause, however, remains debatable. Objective: To explore whether local hepcidin synthesized by brain cells contributes to iron accumulation
Autor:
Neil A. Rana, Alexander E. Kritikos, Suman Chaudhary, Neena Singh, Vindhya Bellamkonda, Dallas McDonald, Rithvik V Ayyagari, Ajay Ashok, Aaron S. Wise
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 7290, p 7290 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 7290, p 7290 (2020)
Age-related macular degeneration (AMD) and glaucoma are degenerative conditions of the retina and a significant cause of irreversible blindness in developed countries. Alzheimer’s disease (AD), the most common dementia of the elderly, is often asso
Autor:
Neil A. Rana, Ajay Ashok, Aaron S. Wise, Neena Singh, Ewald Lindner, Suman Chaudhary, Alexander E. Kritikos
Publikováno v:
Exp Eye Res
Recently, we reported β-cleavage of the prion protein (PrP(C)) in human ocular tissues. Here, we explored whether this is unique to the human eye, and its functional implications. A comparison of the cleavage pattern of PrP(C) in human ocular tissue