Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Neil A. Littlefield"'
Autor:
Bruce S. Hass, Neil A. Littlefield, Ildikó Csuka, Marina Mikhailova, Gaspar Banfalvi, Ming Wu Chou, Edit Szepessy
Publikováno v:
European Journal of Biochemistry. 267:6580-6585
Repair and replicative DNA synthesis were measured at different stages of the cell cycle in control and cadmium-treated Chinese hamster ovary (CHO-K1) cells. Cells were synchronized by counterflow centrifugal elutriation. Elutriation resulted in five
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::438efdf8d4c273072814bbd608cae089
https://doi.org/10.1046/j.1432-1327.2000.01751.x
https://doi.org/10.1046/j.1432-1327.2000.01751.x
Publikováno v:
International Journal of Toxicology. 18:297-306
The aim of this study was to develop an in vitro model to investigate the molecular mechanisms of glucose-induced inhibition of cell proliferation. HuH7 cells were grown in the presence or absence of glucose for 7 days and cell proliferation was stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca699f35eee2ce169cf9cb5a79e318f9
https://doi.org/10.1080/109158199225215
https://doi.org/10.1080/109158199225215
Publikováno v:
Cell Biology and Toxicology. 10:127-135
Magnesium, an essential metal that is important in the normal functioning of DNA, has been shown to interact with some of the toxic heavy metals in respect to biochemical and molecular mechanisms and in altering the tumorigenic process. This study ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15f29f984784663df733c91b904f320
https://doi.org/10.1007/bf00756493
https://doi.org/10.1007/bf00756493
Publikováno v:
Cancer letters. 115(2)
The effect of cadmium ion (Cd) and ascorbic acid (Asc) on the induction of oxidative DNA damage and on the activities of antioxidant enzymes were investigated in human lymphoblastoid cells (AHH-1 TK+/-). Cd at low concentrations of 5-35 microM induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc094e0ffec80b1f94ba54c0a06d621
https://pubmed.ncbi.nlm.nih.gov/9149117
https://pubmed.ncbi.nlm.nih.gov/9149117
Publikováno v:
Chemico-biological interactions. 79(2)
Nickel (Ni), a carcinogenic and genotoxic metal, has been shown to enhance deglycosylation and hydroxylation of 2′-deoxyguanosine (dG) that has been caused by ascorbic acid and H2O2. There is evidence that Mg is a competitive antagonist of the toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af16631867ad0e5c371a9b8e00b709ab
https://pubmed.ncbi.nlm.nih.gov/1884431
https://pubmed.ncbi.nlm.nih.gov/1884431
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 28(3)
Fischer 344 rats were given 10, 40, 600, 1200 or 2400 ppm sulphamethazine (SMZ) in the diet to determine the toxicity and potential carcinogenicity of SMZ. There were 225 rats of each sex in the control groups and 135 of each sex in each dose group.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb22464f047ab7e26d96c30ef0a56b9
https://pubmed.ncbi.nlm.nih.gov/2344990
https://pubmed.ncbi.nlm.nih.gov/2344990
Publikováno v:
Fundamental and Applied Toxicology. 3:3a-8a
This communication has re-examined and justified certain of the NCTR's analyses and recommendations from the ED01 Study, which were either misunderstood or misinterpreted by the SOT Task Force. In addition, we have shown that some of the Task Force's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de61c31bd6b25e9ceff7eb1cc72e839
https://doi.org/10.1016/s0272-0590(83)80150-x
https://doi.org/10.1016/s0272-0590(83)80150-x
Publikováno v:
Fundamental and Applied Toxicology. 5:902-912
Gentian violet is a dye belonging to a chemical class known as the di- and triaminophenylmethanes. Although it has been used for many years for the control of fungal and intestinal parasites, for various uses in veterinary medicine, and as an additiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8eda1c055e74395d705aac1a20b3bdb
https://doi.org/10.1016/0272-0590(85)90172-1
https://doi.org/10.1016/0272-0590(85)90172-1
Publikováno v:
JNCI: Journal of the National Cancer Institute. 54:257-261
Studies were made on the urinary bladder of 66 BALB/c mice of both sexes; 21 were fed a normal diet and 45, a diet containing 100-500 parts per million (ppm) of 2-acetylaminofluorene (2-AAF). Bladder epithelial hyperplasia was noted in 22 of 24 mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02f04eca473b22132dfc6e764aacb170
https://doi.org/10.1093/jnci/54.1.257
https://doi.org/10.1093/jnci/54.1.257
Autor:
Neil A. Littlefield, Ralph L. Kodell
Publikováno v:
Journal of Toxicology and Environmental Health. 5:121-129
The importance of the genetic makeup of animals used for toxicological testing has been recognized, although there are few data regarding this. In the study discussed here offspring from a BALB/cStCrlfC3Hf/Nctr male and C57BL/6/fC3Hf/Nctr female cros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd4d04edea45b6dc76a98ec982078c7
https://doi.org/10.1080/15287397909529730
https://doi.org/10.1080/15287397909529730