Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Neil A Hukriede"'
Autor:
Cheng Cui, Bishwanath Chatterjee, Thomas P Lozito, Zhen Zhang, Richard J Francis, Hisato Yagi, Lisa M Swanhart, Subramaniam Sanker, Deanne Francis, Qing Yu, Jovenal T San Agustin, Chandrakala Puligilla, Tania Chatterjee, Terry Tansey, Xiaoqin Liu, Matthew W Kelley, Elias T Spiliotis, Adam V Kwiatkowski, Rocky Tuan, Gregory J Pazour, Neil A Hukriede, Cecilia W Lo
Publikováno v:
PLoS Biology, Vol 11, Iss 11, p e1001720 (2013)
Planar cell polarity (PCP) regulates cell alignment required for collective cell movement during embryonic development. This requires PCP/PCP effector proteins, some of which also play essential roles in ciliogenesis, highlighting the long-standing q
Externí odkaz:
https://doaj.org/article/74d38beca1bc443a9a89ee1c2c5aae74
Autor:
Shalini Mitra, Stefan Lukianov, Wily G Ruiz, Chiara Cianciolo Cosentino, Subramaniam Sanker, Linton M Traub, Neil A Hukriede, Gerard Apodaca
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41816 (2012)
Uroplakin (UP)3a is critical for urinary tract development and function; however, its role in these processes is unknown. We examined the function of the UP3a-like protein Upk3l, which was expressed at the apical surfaces of the epithelial cells that
Externí odkaz:
https://doaj.org/article/a4e781c4d24349a2aff02a86fae7914e
Autor:
M Cecilia Cirio, Zhao Hui, Caroline E Haldin, Chiara Cianciolo Cosentino, Carsten Stuckenholz, Xiongfong Chen, Sung-Kook Hong, Igor B Dawid, Neil A Hukriede
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18858 (2011)
In the vertebrate embryo, the kidney is derived from the intermediate mesoderm. The LIM-class homeobox transcription factor lhx1 is expressed early in the intermediate mesoderm and is one of the first genes to be expressed in the nephric mesenchyme.
Externí odkaz:
https://doaj.org/article/3102822b6cc94763a1049ea3915ef634
Autor:
Ailen S. Cervino, Mariano G. Collodel, Ivan A. Lopez, Carolina Roa, Daniel Hochbaum, Neil A. Hukriede, M. Cecilia Cirio
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The nephron, functional unit of the vertebrate kidney, is specialized in metabolic wastes excretion and body fluids osmoregulation. Given the high evolutionary conservation of gene expression and segmentation patterning between mammalian and
Externí odkaz:
https://doaj.org/article/089ae6f0fc5d4ab59f9a14008960313a
Autor:
Nicolas Montalbetti, Aneta J. Przepiorski, Shujie Shi, Shaohu Sheng, Catherine J. Baty, Joseph C. Maggiore, Marcelo D. Carattino, Thitinee Vanichapol, Alan J. Davidson, Neil A. Hukriede, Thomas R. Kleyman
Publikováno v:
American Journal of Physiology-Renal Physiology. 323:F479-F491
Kidney organoids derived from human or rodent pluripotent stem cells have glomerular structures and differentiated/polarized nephron segments. Although there is an increasing understanding of the patterns of expression of transcripts and proteins wit
Autor:
Joseph C Maggiore, Ryan LeGraw, Aneta Przepiorski, Jeremy Velazquez, Christopher Chaney, Evan Streeter, Anne Silva-Barbosa, Jonathan Franks, Joshua Hislop, Alex Hill, Haojia Wu, Katherine Pfister, Sara E Howden, Simon C Watkins, Melissa Little, Benjamin Humphreys, Alan Watson, Donna B Stolz, Samira Kiani, Alan J Davidson, Thomas J. Carroll, Ondine J. Cleaver, Sunder Sims-Lucas, Mo R Ebrahimkhani, Neil A Hukriede
Vascularization plays a critical role in organ maturation and cell type development. Drug discovery, organ mimicry, and ultimately transplantation in a clinical setting thereby hinges on achieving robust vascularization of in vitro engineered organs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a832bb2fd956b83cba53f6fdf775582
https://doi.org/10.1101/2023.05.30.542848
https://doi.org/10.1101/2023.05.30.542848
Autor:
Andreas Vogt, Billy W. Day, Dennis P. Curran, Neil A. Hukriede, John S. Lazo, Celeste E. Reese, Raghavan Balachandran, Hikmat N. Daghestani, Wei Zhu, Daniel P. Camarco, Maria Jiménez, Laura L. Vollmer
The natural product (−)-dictyostatin is a microtubule-stabilizing agent that potently inhibits the growth of human cancer cells, including paclitaxel-resistant clones. Extensive structure–activity relationship studies have revealed several region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecdf80d5efb235382c6a7baaca49a0a2
https://doi.org/10.1158/1535-7163.c.6535479
https://doi.org/10.1158/1535-7163.c.6535479
Autor:
Andreas Vogt, Billy W. Day, Dennis P. Curran, Neil A. Hukriede, John S. Lazo, Celeste E. Reese, Raghavan Balachandran, Hikmat N. Daghestani, Wei Zhu, Daniel P. Camarco, Maria Jiménez, Laura L. Vollmer
Supplementary Tables 1-2,Characterization Data & References from A Simplified Synthesis of Novel Dictyostatin Analogues with In Vitro Activity against Epothilone B–Resistant Cells and Antiangiogenic Activity in Zebrafish Embryos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fec54cded103cf86b1a690df8d0627
https://doi.org/10.1158/1535-7163.22497030.v1
https://doi.org/10.1158/1535-7163.22497030.v1
Autor:
Andreas Vogt, Billy W. Day, Dennis P. Curran, Neil A. Hukriede, John S. Lazo, Celeste E. Reese, Raghavan Balachandran, Hikmat N. Daghestani, Wei Zhu, Daniel P. Camarco, Maria Jiménez, Laura L. Vollmer
NMR Spectra from A Simplified Synthesis of Novel Dictyostatin Analogues with In Vitro Activity against Epothilone B–Resistant Cells and Antiangiogenic Activity in Zebrafish Embryos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45de1697f469204b948471244ec8f90e
https://doi.org/10.1158/1535-7163.22497033
https://doi.org/10.1158/1535-7163.22497033
Autor:
Keith Long, Zoe Vaughn, Michael David McDaniels, Sipak Joyasawal, Aneta Przepiorski, Emily Parasky, Veronika Sander, David Close, Paul A. Johnston, Alan J. Davidson, Mark de Caestecker, Neil A. Hukriede, Donna M. Huryn
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Acute kidney injury (AKI), a sudden loss of kidney function, is a common and serious condition for which there are no approved specific therapies. While there are multiple approaches to treat the underlying causes of AKI, no targets