Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Neil A, Mabbott"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Prion diseases are fatal, infectious, neurodegenerative disorders resulting from accumulation of misfolded cellular prion protein in the brain. Early pathological changes during CNS prion disease also include reactive astrocyte activation wi
Externí odkaz:
https://doaj.org/article/6f6a57c17f9442f28671aebc8659aa08
Autor:
Neil A. Mabbott, Koji Hase
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/017f85d2374c43aca733b51bc29c55cc
Autor:
Omar A. Alfituri, Rosemary Blake, Kirsty Jensen, Neil A. Mabbott, Jayne Hope, Joanne M. Stevens
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Infection of ruminants such as cattle with Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne’s disease, a disease characterized by chronic inflammation of the small intestine and diarrhoea. Infection with MAP is acquired via the faecal
Externí odkaz:
https://doaj.org/article/c46f11982727446aaa5f60487de4383c
Autor:
Matthew C. Sinton, Praveena R. G. Chandrasegaran, Paul Capewell, Anneli Cooper, Alex Girard, John Ogunsola, Georgia Perona-Wright, Dieudonné M Ngoyi, Nono Kuispond, Bruno Bucheton, Mamadou Camara, Shingo Kajimura, Cécile Bénézech, Neil A. Mabbott, Annette MacLeod, Juan F. Quintana
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract In the skin, Trypanosoma brucei colonises the subcutaneous white adipose tissue, and is proposed to be competent for forward transmission. The interaction between parasites, adipose tissue, and the local immune system is likely to drive the
Externí odkaz:
https://doaj.org/article/34a1cb8324534887a960552c5aa36b6f
Autor:
Christopher H. Herbst, Aurélie Bouteau, Evelin J. Menykő, Zhen Qin, Ervin Gyenge, Qingtai Su, Vincent Cooper, Neil A. Mabbott, Botond Z. Igyártó
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109119- (2024)
Summary: In a previous report, keratinocytes were shown to share their gene expression profile with surrounding Langerhans cells (LCs), influencing LC biology. Here, we investigated whether transferred material could substitute for lost gene products
Externí odkaz:
https://doaj.org/article/e7eedd8056884e228fd575bccf9b35a0
Autor:
Juan F. Quintana, Matthew C. Sinton, Praveena Chandrasegaran, Agatha Nabilla Lestari, Rhiannon Heslop, Bachar Cheaib, John Ogunsola, Dieudonne Mumba Ngoyi, Nono-Raymond Kuispond Swar, Anneli Cooper, Neil A. Mabbott, Seth B. Coffelt, Annette MacLeod
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract African trypanosomes colonise the skin to ensure parasite transmission. However, how the skin responds to trypanosome infection remains unresolved. Here, we investigate the local immune response of the skin in a murine model of infection usi
Externí odkaz:
https://doaj.org/article/9a96c210c22f4f58b0bd9fc2f4ee75ce
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/393cff552d5548aa8fc03aaf817ca73c
Autor:
Juan F Quintana, Matthew C Sinton, Praveena Chandrasegaran, Lalit Kumar Dubey, John Ogunsola, Moumen Al Samman, Michael Haley, Gail McConnell, Nono-Raymond Kuispond Swar, Dieudonné Mumba Ngoyi, David Bending, Luis de Lecea, Annette MacLeod, Neil A Mabbott
Publikováno v:
PLoS Biology, Vol 21, Iss 11, p e3002389 (2023)
The meningeal space is a critical brain structure providing immunosurveillance for the central nervous system (CNS), but the impact of infections on the meningeal immune landscape is far from being fully understood. The extracellular protozoan parasi
Externí odkaz:
https://doaj.org/article/253eccf81f604fb09b7c9c3cff71ce65
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-16 (2023)
Abstract Enteroids are miniature self-organising three-dimensional (3D) tissue cultures which replicate much of the complexity of the intestinal epithelium. We recently developed an apical-out leukocyte-containing chicken enteroid model providing a n
Externí odkaz:
https://doaj.org/article/7fcc1f34f5d047b3bdd6cac8761c4fe5
Autor:
Matthew C. Sinton, Praveena R. G. Chandrasegaran, Paul Capewell, Anneli Cooper, Alex Girard, John Ogunsola, Georgia Perona-Wright, Dieudonné M Ngoyi, Nono Kuispond, Bruno Bucheton, Mamadou Camara, Shingo Kajimura, Cécile Bénézech, Neil A. Mabbott, Annette MacLeod, Juan F. Quintana
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/51277c3f39fe43e394b3a5b030e6202a