Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Neil Ryan"'
Autor:
Gareth Evans, Tjalling Bosse, David N Church, Noel de Miranda, James Bolton, Neil Ryan, Emma Crosbie, Thomas Walker, Marieke Ijsselsteijn, Mark Glaire, Natalja ter Haar
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective To explore the impact of molecular subtype in endometrial cancer (EC) on CD8+T cell densities. Furthermore, this work will test the assumption that all mismatch repair deficient (MMRd) tumours are immunologically similar which would enable
Externí odkaz:
https://doaj.org/article/0d7d9326c85c4ec0a50f47499e3953a4
Autor:
Pal Møller, Toni T. Seppälä, Aysel Ahadova, Emma J. Crosbie, Elke Holinski-Feder, Rodney Scott, Saskia Haupt, Gabriela Möslein, Ingrid Winship, Sanne W. Bajwa-ten Broeke, Kelly E. Kohut, Neil Ryan, Peter Bauerfeind, Laura E. Thomas, D. Gareth Evans, Stefan Aretz, Rolf H. Sijmons, Elizabeth Half, Karl Heinimann, Karoline Horisberger, Kevin Monahan, Christoph Engel, Giulia Martina Cavestro, Robert Fruscio, Naim Abu-Freha, Levi Zohar, Luigi Laghi, Lucio Bertario, Bernardo Bonanni, Maria Grazia Tibiletti, Leonardo S. Lino-Silva, Carlos Vaccaro, Adriana Della Valle, Benedito Mauro Rossi, Leandro Apolinário da Silva, Ivana Lucia de Oliveira Nascimento, Norma Teresa Rossi, Tadeusz Dębniak, Jukka-Pekka Mecklin, Inge Bernstein, Annika Lindblom, Lone Sunde, Sigve Nakken, Vincent Heuveline, John Burn, Eivind Hovig, Matthias Kloor, Julian R. Sampson, Mev Dominguez-Valentin, On behalf of the Prospective Lynch Syndrome Database (www.plsd.eu) and The European Hereditary Tumour Group (www.ehtg.org)
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract The recognition of dominantly inherited micro-satellite instable (MSI) cancers caused by pathogenic variants in one of the four mismatch repair (MMR) genes MSH2, MLH1, MSH6 and PMS2 has modified our understanding of carcinogenesis. Inherited
Externí odkaz:
https://doaj.org/article/952d37829e8040c192582717c1ee47f5
Autor:
Frances Elmslie, Anna Kim, Kevin J Monahan, Francesca Faravelli, Fiona Lalloo, David N Church, Jackie Cook, Tracie Miles, Neil Ryan, Steven A Hardy, Sally Lane, Alaa Elghobashy, Laura Monje-Garcia, Adam C Shaw, Simone Gelinas, Adele Tyson, Ruth Armstrong, Frank D McDermott, Valerie Ya Wen Wang
Publikováno v:
BMJ Oncology, Vol 2, Iss 1 (2023)
Objective In England, through the Genomic Medicine Service Alliances (GMSAs), a national transformation project aims to embed robust pathways to deliver universal Lynch syndrome (LS) testing for patients with colorectal and endometrial cancers. Prior
Externí odkaz:
https://doaj.org/article/358da55ca3114dd4a47d74308a5c3a0d
Autor:
Emma Hazelwood, Eleanor Sanderson, Vanessa Y. Tan, Katherine S. Ruth, Timothy M. Frayling, Niki Dimou, Marc J. Gunter, Laure Dossus, Claire Newton, Neil Ryan, Dimitri J. Pournaras, Tracy A. O’Mara, George Davey Smith, Richard M. Martin, James Yarmolinsky
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-24 (2022)
Abstract Background Endometrial cancer is the most common gynaecological cancer in high-income countries. Elevated body mass index (BMI) is an established modifiable risk factor for this condition and is estimated to confer a larger effect on endomet
Externí odkaz:
https://doaj.org/article/2395cf35177a4574b37ad26ca8a7899e
Person-based co-design of a decision aid template for people with a genetic predisposition to cancer
Autor:
Kate Morton, Kelly Kohut, Lesley Turner, Sian Smith, Emma J. Crosbie, Neil Ryan, Chloe Grimmett, Diana M. Eccles, Claire Foster, The CanGene CanVar Patient Reference Panel, The International Lynch Decision Aid Stakeholder (LDAS) Panel
Publikováno v:
Frontiers in Digital Health, Vol 4 (2022)
BackgroundPeople with genetic predispositions to cancer are faced with complex health decisions about managing their risk. Decision aids can support informed, values-based decisions, alongside shared decision-making with a clinician. Whilst diagnoses
Externí odkaz:
https://doaj.org/article/9177da0d0f274a789bb36d12f387e836
Autor:
Chappell, Neil Ryan, Barsky, Maya, Shah, Jaimin, Peavey, Mary, Yang, Liubin, Sangi-Haghpeykar, Haleh, Gibbons, William, Blesson, Chellakkan Selvanesan
Publikováno v:
In F&S Reports September 2020 1(2):125-132
Autor:
Neil Ryan Chappell, M.D., Maya Barsky, M.D., Jaimin Shah, M.D., Mary Peavey, M.D., Liubin Yang, M.D., Ph.D., Haleh Sangi-Haghpeykar, Ph.D., William Gibbons, M.D., Chellakkan Selvanesan Blesson, M.Phil, Ph.D.
Publikováno v:
F&S Reports, Vol 1, Iss 2, Pp 125-132 (2020)
Objective: To investigate if patients with polycystic ovary syndrome (PCOS) have altered embryo morphokinetics when compared with controls. Design: Retrospective cohort analysis. Setting: Single academic fertility clinic in a tertiary hospital settin
Externí odkaz:
https://doaj.org/article/41d1ea578be14092b3962acd8a3b6b0a
Publikováno v:
Post Reproductive Health. 29:42-52
path_ BRCA 1/2 increases a woman’s lifetime risk of breast and ovarian cancer. Interventions can be offered which manage cancer risk; annual breast screening from age 30, chemoprevention and, once a woman’s family is complete, risk-reducing surge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::829739ccbf0bfbac3bfe2baba4f7f6cb
https://doi.org/10.1177/20533691231156640
https://doi.org/10.1177/20533691231156640
Autor:
Neil Ryan Ado, REY ALMER GINDAP
Publikováno v:
International Multidisciplinary Research Journal. 4:138-148
The recent data disclosed that more than 50 percent of the countries worldwide and most of the ASEAN countries scored below average in the Science subjects. Furthermore, due to the pandemic, online or e-learning is the most effective way to continue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00c5c7c59de10926813ead30691c78d5
https://doi.org/10.54476/ioer-imrj/44714
https://doi.org/10.54476/ioer-imrj/44714
Autor:
Nicola Flaum, Emma J Crosbie, Emma Roisin Woodward, Fiona Lalloo, Robert Morgan, Neil Ryan, D Gareth Evans
Publikováno v:
Flaum, N, Crosbie, E J, Lalloo, F, Morgan, R, Ryan, N & Evans, D G 2023, ' MSH2is the very young onset ovarian cancer predisposition gene, notBRCA1 ', Journal of Medical Genetics . https://doi.org/10.1136/jmg-2022-109055
Flaum, N, Crosbie, E J, Woodward, E R, Lalloo, F, Morgan, R, Ryan, N & Evans, D G 2023, ' MSH2 is the very young onset ovarian cancer predisposition gene, not BRCA1 ', Journal of Medical Genetics . https://doi.org/10.1136/jmg-2022-109055
Flaum, N, Crosbie, E J, Woodward, E R, Lalloo, F, Morgan, R, Ryan, N & Evans, D G 2023, ' MSH2 is the very young onset ovarian cancer predisposition gene, not BRCA1 ', Journal of Medical Genetics . https://doi.org/10.1136/jmg-2022-109055
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a4d90271983fca89dabf9fd560449d6
https://research.manchester.ac.uk/en/publications/50ac61ae-4138-490d-9f61-a3e60aba67e0
https://research.manchester.ac.uk/en/publications/50ac61ae-4138-490d-9f61-a3e60aba67e0
