Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Neil, Rajan"'
Autor:
Abigail Gault, Linda Hogarth, Kristian C Williams, Alastair Greystoke, Neil Rajan, Ally Speight, Christopher A Lamb, Alison Bridgewood, Lisa-Jayne Brown-Schofield, Fiona Rayner, John D Isaacs, Jérémie Nsengimana, Christopher J Stewart, Amy E Anderson, Ruth Plummer, Arthur G Pratt
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Checkpoint inhibitors (CPIs) are widely used in cancer treatment, with transformative impacts on survival. They nonetheless carry a significant risk of toxicity in the form of immune-related adverse events (IrAEs), which may be su
Externí odkaz:
https://doaj.org/article/e1ba05f0593545e687f9967895eaede1
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/e06dc8e6a4584725ab2c97086fac24bc
Autor:
Anna Dubois, BSc, MBChB, William Fostier, BSc, MBBS, James Sampson, MBBS, Justin Durham, BDS, PhD, Neil Rajan, MBBS, PhD
Publikováno v:
JAAD Case Reports, Vol 28, Iss , Pp 110-112 (2022)
Externí odkaz:
https://doaj.org/article/a73eb0b9c9e64d1c9a16bde8f1d79998
Autor:
Kristian C. Williams, Abigail Gault, Amy E. Anderson, Christopher J. Stewart, Christopher A. Lamb, R. Ally Speight, Neil Rajan, Ruth Plummer, Arthur G. Pratt
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Checkpoint inhibitors (CPIs) are monoclonal antibodies which, by disrupting interactions of immune checkpoint molecules with their ligands, block regulatory immune signals otherwise exploited by cancers. Despite revolutionary clinical benefits, CPI u
Externí odkaz:
https://doaj.org/article/b30251e406b74de18123be0e7551e13b
Autor:
Helen R. Davies, Kirsty Hodgson, Edward Schwalbe, Jonathan Coxhead, Naomi Sinclair, Xueqing Zou, Simon Cockell, Akhtar Husain, Serena Nik-Zainal, Neil Rajan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
CYLD cutaneous syndrome (also known as Brooke-Spiegler syndrome) is characterised by germline mutations in the tumor suppressor CYLD. Here, the authors highlight recurrent mutations in DNMT3A and BCOR, indicating a role for epigenetic dysregulation i
Externí odkaz:
https://doaj.org/article/455161ea0e7d48609e0545f51dafe8d6
Autor:
Jilse Joshy, Birgitta van Bodegraven, Khaylen Mistry, Paul Craig, Neil Rajan, Sally Vernon, Nick J Levell, Zoe C Venables
Background Porocarcinoma (PC) is a cutaneous malignancy that differentiates towards (possibly arises from) the sweat ducts and glands. Lack of histological diagnostic markers makes clinical and pathological diagnosis complex. The limited data availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71121e5242c105bcfaca868e26a7d835
https://ueaeprints.uea.ac.uk/id/eprint/92016/
https://ueaeprints.uea.ac.uk/id/eprint/92016/
Autor:
Sam Cook, Joanna Pethick, Nour Kibbi, Loes Hollestein, Katrina Lavelle, Isabella de Vere Hunt, Clare Turnbull, Brian Rous, Akhtar Husain, John Burn, Margreet Lüchtenborg, Francesco Santaniello, Fiona McRonald, Steven Hardy, Eleni Linos, Zoe Venables, Neil Rajan
Publikováno v:
Journal of the American Academy of Dermatology. Mosby Inc.
Background: Sebaceous carcinomas (SC) may be associated with the cancer predisposition syndrome Muir-Torre/Lynch syndrome (MTS/LS), identifiable by SC mismatch repair (MMR) screening; however, there is limited data on MMR status of SC. Objective: To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef83bca614fc62bd5856d07401572c3b
https://doi.org/10.1016/j.jaad.2023.03.046
https://doi.org/10.1016/j.jaad.2023.03.046
Autor:
Nolan J. Maloney, Natasha C. Zacher, Kelsey E. Hirotsu, Neil Rajan, Sumaira Z. Aasi, Nour Kibbi
Publikováno v:
Journal of the American Academy of Dermatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fb4f8627887175625c3e174893233a6
https://doi.org/10.1016/j.jaad.2023.03.032
https://doi.org/10.1016/j.jaad.2023.03.032
Publikováno v:
British Journal of Dermatology. 186:167-173
Summary Background Skin adnexal tumours (SATs) comprise a diverse range of neoplasms, which are difficult to diagnose clinically. They present in paediatric and adult populations, and may be indicative of an underlying genetic syndrome. There is a la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79989f0a910c6644bb979b46c34b327e
https://doi.org/10.1111/bjd.20701
https://doi.org/10.1111/bjd.20701