A locus identified on chromosome18p11.31 is associated with hippocampal abnormalities in a family with mesial temporal lobe epilepsy

Autor: Claudia Vianna Maurer-Morelli, Rodrigo eSecolin, Marcia Elisabete eMorita, Romenia Ramos Domingues, Rafael Breglio Marchesini, Neide Ferreira Santos, Eliane eKobayashi, Fernando eCendes, Iscia eLopes-Cendes

Publikováno v: Frontiers in Neurology, Vol 3 (2012)

We aimed to identify the region harboring a putative candidate gene associated with hippocampal abnormalities (HAb) in a family with mesial temporal lobe epilepsy (MTLE). Genome-wide scan was performed in one large kindred with MTLE using a total of

Externí odkaz: https://doaj.org/article/0f5f8aa078f14142b2c4490fb5d72762

Linkage study of voltage-gated potassium channels in familial mesial temporal lobe epilepsy

Autor: Rodrigo Secolin, Iscia Lopes-Cendes, Cláudia Vianna Maurer-Morelli, Fernando Cendes, Neide Ferreira Santos, Rafael Breglio Marchesini, Eliane Kobayashi

Publikováno v: Arquivos de Neuro-Psiquiatria, Volume: 65, Issue: 1, Pages: 20-23, Published: MAR 2007
Arquivos de Neuro-Psiquiatria v.65 n.1 2007
Arquivos de neuro-psiquiatria
Academia Brasileira de Neurologia
instacron:ABNEURO

Voltage-gated potassium channels (VGKCs) play a critical role in the regulation of neuronal excitability and have been implicated in some types of epilepsies. Recently, autoimmune limbic encephalitis (LE) was associated with antibodies against VGKC.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fc244551c157a983fafff61e42a41c
https://doi.org/10.1590/s0004-282x2007000100006

Congenital bilateral perisylvian syndrome: familial occurrence, clinical and psycholinguistic aspects correlated with MRI

Autor: Simone Rocha de Vasconcellos Hage, Fernando Cendes, Karine C. S. Teixeira, Maria Augusta Montenegro, Neide Ferreira Santos, Iscia Lopes-Cendes, Iara L. Brandão-Almeida, Dagma Venturini Marques Abramides, Ecila Paula dos Mesquita de Oliveira, M M Guerreiro, Catarina A. Guimarães

Publikováno v: Neuropediatrics. 39(3)

Objective Congenital bilateral perisylvian syndrome (CBPS) is frequently caused by polymicrogyria (PMG). The aim of this study was to correlate the clinical and psycholinguistic aspects with neuroradiological data of patients with CBPS. Methods Thirt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d188404c8007d6f14c1b3a0f31f97c
https://pubmed.ncbi.nlm.nih.gov/18991192

THE SCN2A gene is not a likely candidate for familial mesial temporal lobe epilepsy

Autor: Fernando Cendes, Neide Ferreira Santos, Cláudia Vianna Maurer-Morelli, Rodrigo Secolin, Iscia Lopes-Cendes, Rafael Breglio Marchesini, Eliane Kobayashi

Publikováno v: Epilepsy research. 71(2-3)

A transgenic mouse model carrying a mutation in the Scn2a gene showed chronic focal seizures associated with extensive cell loss and gliosis in the hippocampus, a similar phenotype found in familial mesial temporal lobe epilepsy (FMTLE). Our objectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423678912d764fb99441552267c4a9dd
https://pubmed.ncbi.nlm.nih.gov/16914293

Magnetic Resonance Imaging Abnormalities in Familial Temporal Lobe Epilepsy With Auditory Auras

Autor: Rodrigo Secolin, Fernando Cendes, Eliane Kobayashi, Neide Ferreira Santos, Luiz A. C. Sardinha, Iscia Lopez-Cendes, Fábio R. Torres

Publikováno v: Archives of Neurology. 60:1546

Background Two forms of familial temporal lobe epilepsy (FTLE) have been described: mesial FTLE and FTLE with auditory auras. The gene responsible for mesial FTLE has not been mapped yet, whereas mutations in theLGI1(leucine-rich, glioma-inactivated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f44287320bb5e5572c333b402c3e9be
https://doi.org/10.1001/archneur.60.11.1546