Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Nei-Li Chan"'
Autor:
Pei-Fang Hung, Tse-Ming Hong, Che-Chang Chang, Chung-Lieh Hung, Yuan-Ling Hsu, Yih-Leong Chang, Chen-Tu Wu, Gee-Chen Chang, Nei-Li Chan, Sung-Liang Yu, Pan-Chyr Yang, Szu-Hua Pan
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-19 (2019)
Abstract Background The Slug-E-cadherin axis plays a critical role in non-small-cell lung cancers (NSCLCs) where aberrant upregulation of Slug promotes cancer metastasis. Now, the post-translational modifications of Slug and their regulation mechanis
Externí odkaz:
https://doaj.org/article/0c653f4287a04795a807f3dc8350f7ad
Autor:
Shin-Fu Chen, Nan-Lan Huang, Jung-Hsin Lin, Chyuan-Chuan Wu, Ying-Ren Wang, Yu-Jen Yu, Michael K. Gilson, Nei-Li Chan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Type II DNA topoisomerases (Top2s) direct the passage of one DNA duplex through another, which is important for resolving DNA entanglements. Here the authors combine X-ray crystallography and MD simulations and present the structure of the human Top2
Externí odkaz:
https://doaj.org/article/658289d67ad24135b29bba4a1384fb23
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The programmed induction of meiotic DNA double-strand breaks (DSBs) by the evolutionarily conserved SPO-11 protein, which is structurally related to archaeal Topo VIA topoisomerases, triggers meiotic recombination. Identification of several
Externí odkaz:
https://doaj.org/article/cac9161265444b8b8f35082c0e583989
Autor:
Bo-Chi Lin, Li-Hsin Su, Shih-Che Weng, Yu-Jiao Pan, Nei-Li Chan, Tsai-Kun Li, Hsin-Chih Wang, Chin-Hung Sun
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 1, p e0005326 (2017)
[This corrects the article DOI: 10.1371/journal.pntd.0002218.].
Externí odkaz:
https://doaj.org/article/c61861526e6c4fdcb70041e840ae0fe9
Autor:
Bo-Chi Lin, Li-Hsin Su, Shih-Che Weng, Yu-Jiao Pan, Nei-Li Chan, Tsai-Kun Li, Hsin-Chih Wang, Chin-Hung Sun
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 5, p e2218 (2013)
The protozoan Giardia lamblia differentiates into infectious cysts within the human intestinal tract for disease transmission. Expression of the cyst wall protein (cwp) genes increases with similar kinetics during encystation. However, little is know
Externí odkaz:
https://doaj.org/article/dc89838426b646bea82c714a721a34d4
Autor:
Shu-Chun Teng, Kou-Juey Wu, Nei-Li Chan, Ming-Chieh Lin, Wen-Hung Kuo, I-Chen Wu, Shiou-Ru Tzeng, Chia-Jung Yu, Yun-Ju Chen, Cheng-Hui Tsai
SMYD3 methyltransferase is nearly undetectable in normal human tissues but highly expressed in several cancers, including breast cancer, although its contributions to pathogenesis in this setting are unclear. Here we report that histone H2A.Z.1 is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73f2066e0a385a3a21afcc56c1b1f774
https://doi.org/10.1158/0008-5472.c.6508518.v1
https://doi.org/10.1158/0008-5472.c.6508518.v1
Autor:
Shu-Chun Teng, Kou-Juey Wu, Nei-Li Chan, Ming-Chieh Lin, Wen-Hung Kuo, I-Chen Wu, Shiou-Ru Tzeng, Chia-Jung Yu, Yun-Ju Chen, Cheng-Hui Tsai
Fig. S1. Representative mass spectrometry data of methylated H2A.Z. Fig. S2. Methylation activity of SMYD3 on histones in the context of nucleosome and evaluation of the H2A.ZK101me2 antibody. Fig. S3. Dimethylation of H2A.Z is critical for its prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfbe68815d67c80e450d4a70816885e
https://doi.org/10.1158/0008-5472.22412787
https://doi.org/10.1158/0008-5472.22412787
Autor:
Shu-Chun Teng, Kou-Juey Wu, Nei-Li Chan, Ming-Chieh Lin, Wen-Hung Kuo, I-Chen Wu, Shiou-Ru Tzeng, Chia-Jung Yu, Yun-Ju Chen, Cheng-Hui Tsai
Supplementary Materials and Methods, Supplementary Figure Legends and Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6164d8f76de6f806e6b2d3199404f2
https://doi.org/10.1158/0008-5472.22412784.v1
https://doi.org/10.1158/0008-5472.22412784.v1
Autor:
Shu-Chun Teng, Kou-Juey Wu, Nei-Li Chan, Ming-Chieh Lin, Wen-Hung Kuo, I-Chen Wu, Shiou-Ru Tzeng, Chia-Jung Yu, Yun-Ju Chen, Cheng-Hui Tsai
Supplementary Table S1. List of methylated histone proteins identified from in vitro HMT assay on calf thymus extracts followed by LC-MS/MS analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1d25daf285904cdd53a3475032d87f
https://doi.org/10.1158/0008-5472.22412781
https://doi.org/10.1158/0008-5472.22412781
Autor:
Nei-Li Chan, Yisong Guo, Wei-Chen Chang, Igor V. Kurnikov, Maria Kurnikova, Yijie Tang, Hsuan Jen Liao, Hao-Yu Tang
Publikováno v:
ACS Catal
Nature has developed complexity–generating reactions within natural product biosynthetic pathways. However, direct utilization of these pathways to prepare compound libraries remains challenging due to limited substrate scopes, involvement of multi