Molecular mechanisms of inflammation and tissue injury after major trauma-is complement the 'bad guy'?

Autor: Neher Miriam D, Weckbach Sebastian, Flierl Michael A, Huber-Lang Markus S, Stahel Philip F

Publikováno v: Journal of Biomedical Science, Vol 18, Iss 1, p 90 (2011)

Abstract Trauma represents the leading cause of death among young people in industrialized countries. Recent clinical and experimental studies have brought increasing evidence for activation of the innate immune system in contributing to the pathogen

Externí odkaz: https://doaj.org/article/f89438e46fad4602a59364ae85f93ff9

Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects

Autor: Denk, Stephanie, Neher, Miriam D, Messerer, David A C, Wiegner, Rebecca, Nilsson, Bo, Rittirsch, Daniel, et al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______885::06497f4806e707cb48d48b57f1c67c6c
https://www.zora.uzh.ch/id/eprint/189917/

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects.

Autor: Denk S; Institute of Clinical and Experimental Trauma-Immunology, University Hospital Ulm, 89081 Ulm, Germany., Neher MD; Institute of Clinical and Experimental Trauma-Immunology, University Hospital Ulm, 89081 Ulm, Germany., Messerer DAC; Institute of Clinical and Experimental Trauma-Immunology, University Hospital Ulm, 89081 Ulm, Germany., Wiegner R; Institute of Clinical and Experimental Trauma-Immunology, University Hospital Ulm, 89081 Ulm, Germany., Nilsson B; Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, 751 85 Uppsala, Sweden., Rittirsch D; Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, 8091 Zurich, Switzerland., Nilsson-Ekdahl K; Linnæus Center of Biomaterials Chemistry, Linnæus University, 391 82 Kalmar, Sweden., Weckbach S; Department of Orthopedic Surgery, Ulm University, University and Rehabilitation Clinics Ulm, 89081 Ulm, Germany., Ignatius A; Institute of Orthopedic Research and Biomechanics, Ulm University, 89081 Ulm, Germany., Kalbitz M; Department of Traumatology, Hand, Plastic, and Reconstructive Surgery, University Hospital Ulm, 89081 Ulm, Germany., Gebhard F; Department of Traumatology, Hand, Plastic, and Reconstructive Surgery, University Hospital Ulm, 89081 Ulm, Germany., Weiss ME; Department of Anesthesiology, University Hospital Ulm, 89081 Ulm, Germany., Vogt J; Institute of Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany., Radermacher P; Institute of Anesthesiological Pathophysiology and Process Engineering, Ulm University, 89081 Ulm, Germany., Köhl J; Institute for Systemic Inflammation Research, University of Lübeck, 23538 Lübeck, Germany.; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229; and., Lambris JD; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Huber-Lang MS; Institute of Clinical and Experimental Trauma-Immunology, University Hospital Ulm, 89081 Ulm, Germany; markus.huber-lang@uniklinik-ulm.de.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2017 Jun 15; Vol. 198 (12), pp. 4846-4854. Date of Electronic Publication: 2017 May 10.