Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nehal Gosalia"'
Autor:
Julie E. Horowitz, Neil Warner, Jeffrey Staples, Eileen Crowley, Nehal Gosalia, Ryan Murchie, Cristopher Van Hout, Karoline Fiedler, Gabriel Welch, Alejandra Klauer King, Jeffrey G. Reid, John D. Overton, Aris Baras, Alan R. Shuldiner, Anne Griffiths, Omri Gottesman, Aleixo M. Muise, Claudia Gonzaga-Jauregui
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Inflammatory bowel disease (IBD), clinically defined as Crohn’s disease (CD), ulcerative colitis (UC), or IBD-unclassified, results in chronic inflammation of the gastrointestinal tract in genetically susceptible hosts. Pediatric onset IBD
Externí odkaz:
https://doaj.org/article/1f5de0d61ecd4e8a964ff8857b3099dd
Autor:
Valerie S Salazar, Luciane P Capelo, Claudio Cantù, Dario Zimmerli, Nehal Gosalia, Steven Pregizer, Karen Cox, Satoshi Ohte, Marina Feigenson, Laura Gamer, Jeffry S Nyman, David J Carey, Aris Economides, Konrad Basler, Vicki Rosen
Publikováno v:
eLife, Vol 8 (2019)
Two decades after signals controlling bone length were discovered, the endogenous ligands determining bone width remain unknown. We show that postnatal establishment of normal bone width in mice, as mediated by bone-forming activity of the periosteum
Externí odkaz:
https://doaj.org/article/9d2b30c5012843a591dbe3bdc1ce4a2e
Autor:
Nehal Gosalia, Ann Harris
Publikováno v:
Genes, Vol 6, Iss 3, Pp 543-558 (2015)
The contribution of chromatin dynamics to the regulation of human disease-associated loci such as the cystic fibrosis transmembrane conductance regulator (CFTR) gene has been the focus of intensive experimentation for many years. Recent technological
Externí odkaz:
https://doaj.org/article/8d80225c3a724e39bbc37ca9065ed035
Autor:
Robert L. Hanson, Clifton Bogardus, Nehal Gosalia, Leslie J. Baier, Robert C. Williams, Alan R. Shuldiner, Cristopher V. Van Hout, Çiğdem Köroğlu, William C. Knowler
Publikováno v:
Hum Immunol
While the samples and data from the Pima Indians of the Gila River Indian Community have been included in many international HLA workshops and conferences and have been the focus of numerous population reports and the source of novel alleles at the c
Autor:
Nehal Gosalia, Cristopher V. Van Hout, John D. Overton, Omri Gottesman, Ryan Murchie, Aris Baras, Alan R. Shuldiner, Claudia Gonzaga-Jauregui, Gabriel Welch, Aleixo M. Muise, Jeffrey G. Reid, Julie E. Horowitz, Karoline Fiedler, Neil Warner, Anne M. Griffiths, Alejandra King, Eileen Crowley, Jeffrey Staples
Publikováno v:
Paediatrics Publications
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Inflammatory bowel disease (IBD), clinically defined as Crohn’s disease (CD), ulcerative colitis (UC), or IBD-unclassified, results in chronic inflammation of the gastrointestinal tract in genetically susceptible hosts. Pediatric onset IBD represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21923c551e5578f0d9e38862eb408d7b
https://ir.lib.uwo.ca/context/paedpub/article/2012/viewcontent/s41598_021_84938_8.pdf
https://ir.lib.uwo.ca/context/paedpub/article/2012/viewcontent/s41598_021_84938_8.pdf
Autor:
Robert L. Hanson, Leslie J. Baier, Nehal Gosalia, Hye In Kim, Çiğdem Köroğlu, Bin Ye, Alan R. Shuldiner, Clifton Bogardus, Cristopher V. Van Hout, Wen-Chi Hsueh, William C. Knowler
Publikováno v:
Am J Hum Genet
Applying exome sequencing to populations with unique genetic architecture has the potential to reveal novel genes and variants associated with traits and diseases. We sequenced and analyzed the exomes of 6,716 individuals from a Southwestern American
Autor:
Robert C. Williams, William C. Knowler, Alan R. Shuldiner, Nehal Gosalia, Cristopher Van Hout, null Regeneron Genetics Center, Robert L. Hanson, Clifton Bogardus, Leslie J. Baier
Publikováno v:
Human Immunology. 80:955-965
The Pima Indians of the Gila River Indian Community in Arizona have participated in a long-range study of type 2 diabetes mellitus since 1965 and have been the subject of HLA typing and population studies since the early days of serological assays. T
Autor:
Jeffrey R. O'Connell, Cristopher V. Van Hout, Vincent See, Kathleen Palmer, Alan R. Shuldiner, Claudia Gonzaga-Jauregui, Elizabeth A. Streeten, Kathleen A. Ryan, Melanie Daue, Dan M. Roden, Tao Yang, Nehal Gosalia, Braxton D. Mitchell, Toni I. Pollin, Amber L. Beitelshees, Kristin A. Maloney, Megan Lynch, James A. Perry, Andrew M. Glazer, Linda B.J. Jeng, Aris N. Economides
Publikováno v:
Circulation: Genomic and Precision Medicine. 13
Background: In population-based research exome sequencing, the path from variant discovery to return of results is not well established. Variants discovered by research exome sequencing have the potential to improve population health. Methods: Popula
Autor:
Leslie J. Baier, William C. Knowler, Clifton Bogardus, Sayuko Kobes, Samantha E. Day, Alan R. Shuldiner, Hye In Kim, Darin Mahkee, Nehal Gosalia, Yunhua L. Muller, Kim Wiedrich, Cris Van Hout, Robert L. Hanson, Bin Ye, Çiğdem Köroğlu
Publikováno v:
Obesity (Silver Spring, Md.)
Objective In an ongoing effort to identify the genetic variation that contributes to obesity in American Indians, known Bardet–Biedl syndrome (BBS) genes were analyzed for an effect on BMI and leptin signaling. Methods Potentially deleterious varia
Autor:
Marylyn D. Ritchie, Colm O'Dushlaine, Aris Baras, Jeffrey D. Reid, Sofiya Milman, Alan R. Shuldiner, Patrick Sin-Chan, Dadong Li, Scott M. Damrauer, David J. Carey, David H. Ledbetter, Nir Barzilai, Cristopher V. Van Hout, David J. Glass, Anthony Marcketta, Nehal Gosalia, Aris N. Economides, Daniel J. Rader, Alexander H. Li, Bin Ye, John D. Overton, Chuan Gao
SUMMARYAging is characterized by degeneration in cellular and organismal functions leading to increased disease susceptibility and death. Although our understanding of aging biology in model systems has increased dramatically, large-scale sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0b9122e0fec6a5f78b11396b9011569
https://doi.org/10.1101/2020.07.19.188789
https://doi.org/10.1101/2020.07.19.188789