Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Neha R. Prasad"'
Autor:
Jeffrey D. Lifson, Christoph H. Fellinger, Michael Farzan, Hema R. Kondur, Kimberly L. Weisgrau, Nancy Schultz-Darken, Guangping Gao, Barnett Alfant, Amber S. Zhou, Wendy Newton, Neha R. Prasad, Meredith E. Davis-Gardner, Matthew R. Gardner, Lisa M. Kattenhorn, Eva G. Rakasz, Jesse A. Weber
A number of simian and simian human immunodeficiency viruses (SIV and SHIV, respectively) have been used to assess the efficacy of HIV-1 vaccine strategies. Among these, SIVmac239 is considered among the most stringent because, unlike SHIV models, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3b092778486d063519fc4db3c02712
https://europepmc.org/articles/PMC6716512/
https://europepmc.org/articles/PMC6716512/
Autor:
Ina Fetzer, Michael Farzan, Jesse A. Weber, Neha R. Prasad, Matthew R. Gardner, Meredith E. Davis-Gardner, Barnett Alfant, Amber S. Zhou
Broadly neutralizing antibodies (bNAbs) target five major epitopes on the HIV-1 envelope glycoprotein (Env). The most potent bNAbs have median half-maximal inhibitory concentration (IC(50)) values in the nanomolar range, and the broadest bNAbs neutra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feadcd4a4f3a78c51fb92920d7447729
https://europepmc.org/articles/PMC6384058/
https://europepmc.org/articles/PMC6384058/
Autor:
Brian D. Quinlan, Michael Farzan, Vinita R. Joshi, Matthew R. Gardner, Christoph H. Fellinger, Neha R. Prasad, Amber S. Zhou, Hema R. Kondur
Publikováno v:
Journal of Virology. 90:7822-7832
The HIV-1 envelope glycoprotein (Env) is a trimer of gp120/gp41 heterodimers that mediates viral entry. Env binds cellular CD4, an association which stabilizes a conformation favorable to its subsequent association with a coreceptor, typically CCR5 o
Autor:
Barnett Alfant, Jesse A. Weber, Michael Farzan, Meredith E. Davis-Gardner, Ina Fetzer, Matthew R. Gardner, Neha R. Prasad
Publikováno v:
Journal of virology. 92(12)
The human immunodeficiency virus type 1 (HIV-1) entry inhibitor eCD4-Ig is a fusion of CD4-Ig and a coreceptor-mimetic peptide. eCD4-Ig is markedly more potent than CD4-Ig, with neutralization efficiencies approaching those of HIV-1 broadly neutraliz