Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Neha Majety"'
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100925- (2021)
Summary: This protocol describes how to identify Dual Expressers (DEs), a rare type of lymphocyte that co-expresses B-cell receptors and T-cell receptors, by flow cytometry using a cocktail of four antibodies. It also shows the subsequent gating stra
Externí odkaz:
https://doaj.org/article/549dab43cfd543839e06f19430a48f87
Autor:
Rizwan Ahmed, Neha Majety, Kevin C. Chan, Adebola Giwa, Joseph Heinemann, Hao Zhang, Joseph Margolick, Rafid Al-Hallaf, Prajita Paul, David R. Bell, Yi Song, Sangyun Lee, Ruhong Zhou, Risa M Wolfe, Thomas Donner, Chunfa Jie, Abdel Rahim A Hamad
T and B cells are the two arms of the adaptive immune system that mediate cellular and humoral immunity, respectively, using highly diverse repertoires of antigen receptors. T cells recognize antigens using the T cell receptor (TCR), whereas B cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99923d1ff7e26a1e18e07ea7b86ad4a3
https://doi.org/10.1101/2023.05.06.539704
https://doi.org/10.1101/2023.05.06.539704
Autor:
Zahra Omidian, Thomas Donner, Sarah M Omer, Neha Majety, Abdel Rahim A. Hamad, Adebola Giwa, Kagan Ege Karakus, Rizwan Ahmed
Publikováno v:
World Journal of Diabetes
Type 1 diabetes (T1D) is an autoimmune disease that usually strikes early in life, but can affect individuals at almost any age. It is caused by autoreactive T cells that destroy insulin-producing beta cells in the pancreas. Epidemiological studies e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baae65a14aec9f9cbcf225fc4e4a63e2
http://europepmc.org/articles/PMC6927819
http://europepmc.org/articles/PMC6927819
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 4, Pp 100925-(2021)
STAR Protocols, Vol 2, Iss 4, Pp 100925-(2021)
Summary This protocol describes how to identify Dual Expressers (DEs), a rare type of lymphocyte that co-expresses B-cell receptors and T-cell receptors, by flow cytometry using a cocktail of four antibodies. It also shows the subsequent gating strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430a7dab6d6cc88924492d082353f9d9
http://europepmc.org/articles/PMC8564191
http://europepmc.org/articles/PMC8564191
Autor:
Patrick Cahan, Stephen Desiderio, Scheherazade Sadegh-Nasseri, Simon Gritsch, Ruhong Zhou, Abdel Rahim A. Hamad, Neha Majety, David R. Bell, Adebola Giwa, Benjamin Cornwell, Aaron W. Michels, Zahra Omidian, Chunfa Jie, Rizwan Ahmed, Thomas Donner, Sangyun Lee, Hao Zhang, Mario L. Suvà, Hamid Rabb
Publikováno v:
Cell
T and B cells are the two known lineages of adaptive immune cells. Here, we describe a previously unknown lymphocyte that is a dual expresser (DE) of TCR and BCR and key lineage markers of both B and T cells. In type 1 diabetes (T1D), DEs are predomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e1f6d08b73000076baae0e3c65139e
https://europepmc.org/articles/PMC7962621/
https://europepmc.org/articles/PMC7962621/
Autor:
Rizwan Ahmed, Zahra Omidian, Adebola Giwa, Kusuma Ananth, kagan Ege Karakus, Mahamoud Aljack, Neha Majety, Angela Yang, Alana Macdonald, Sanjana Tyagi, Hao Zhang, Hamid Rabb, Chunfa Jie, Thomas Donner, Abdel Hamad
Publikováno v:
The Journal of Immunology. 206:21.03-21.03
PURPOSE: We have recently identified a previously unknown lymphocyte that is a dual expresser (DE) of productively rearranged and surface-expressed TCRαβ and BCR (surface immunoglobulin, Ig) (Ahmed et al, Cell, 2019: 177:11583). Importantly, a sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e88d948a0611b6b1fb40be8ea22b67ad
https://doi.org/10.4049/jimmunol.206.supp.21.03
https://doi.org/10.4049/jimmunol.206.supp.21.03
Autor:
Rizwan Ahmed, Zahra Omidian, Adebola Giwa, Kagan E Karakus, Neha Majety, Angela Yang, Hao Zhang, Hamid Rabb, Chunfa Jie, Thomas Donner, Abdel R.A. Hamad
Publikováno v:
The Journal of Immunology. 204:142.10-142.10
PURPOSE We have recently discovered a new lymphocyte that co-express BCR and TCR (Ahmed et al, Cell, 2019: 177:11583) and referred as X cell to denote its crossover phenotype. Importantly, X cells express a public BCR that also encodes a potent autoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da86718b185321e6b0e1d30b3f9bcfd3
https://doi.org/10.4049/jimmunol.204.supp.142.10
https://doi.org/10.4049/jimmunol.204.supp.142.10
Autor:
Andrew J. Krentz
Insulin: Deficiency, Excess and Resistance in Human Disease provides an overview of the role of insulin in the pathogenesis of prevalent non-communicable diseases such as obesity, type 2 diabetes, cardiovascular disease, and cancer, along with a comp