Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Neha Dikshit"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Pathogenic Salmonella serovars are a major cause of enteric illness in humans and animals, and produce clinical manifestations ranging from localized gastroenteritis to systemic disease. T cells are a critical component of immunity against this intra
Externí odkaz:
https://doaj.org/article/4a08a2f3722844799c0f9546cf0b7ce4
Autor:
Pradeep Bist, Wan Shoo Cheong, Aylwin Ng, Neha Dikshit, Bae-Hoon Kim, Niyas Kudukkil Pulloor, Hanif Javanmard Khameneh, Matija Hedl, Avinash R. Shenoy, Vanniarajan Balamuralidhar, Najib Bin Abdul Malik, Michelle Hong, Albert Neutzner, Keh-Chuang Chin, Koichi S. Kobayashi, Antonio Bertoletti, Alessandra Mortellaro, Clara Abraham, John D. MacMicking, Ramnik J. Xavier, Bindu Sukumaran
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Prolonged NOD2 ligand engagement induces tolerance and attenuated NOD2 signalling, but the molecular mechanisms leading to this tolerance induction are unclear. Here the authors show that the degradation of a NOD2 adaptor, RIP2, by the E3 ligase ZNRF
Externí odkaz:
https://doaj.org/article/fcfe5f0cdf014198b141e4fc270fc775
Autor:
Neha Dikshit, Pradeep Bist, Shannon N Fenlon, Niyas Kudukkil Pulloor, Christelle En Lin Chua, Marci A Scidmore, Jason A Carlyon, Bor Luen Tang, Swaine L Chen, Bindu Sukumaran
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005083 (2015)
Recurrent urinary tract infections (UTIs) caused by uropathogenic E. coli (UPEC) are common and morbid infections with limited therapeutic options. Previous studies have demonstrated that persistent intracellular infection of bladder epithelial cells
Externí odkaz:
https://doaj.org/article/ca5da1de1f3b4d359185dc5ce52b13c0
Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP
Autor:
Pradeep Bist, Wan Shoo Cheong, Aylwin Ng, Neha Dikshit, Bae Hoon Kim, Niyas Kudukkil Pulloor, Hanif Javanmard Khameneh, Matija Hedl, Avinash R. Shenoy, Vanniarajan Balamuralidhar, Najib Bin Abdul Malik, Michelle Hong, Albert Neutzner, Keh-Chuang Chin, Koichi S. Kobayashi, Antonio Bertoletti, Alessandra Mortellaro, Clara Abraham, John D. MacMicking, Ramnik J. Xavier, Bindu Sukumaran
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8 Article number: 15865 (2017); Published: 28 June 2017; Updated: 18 August 2017 The previously published version of this Article contained a line number in the Abstract within the sentence ‘A fraction of RIP2 localizes to the
Externí odkaz:
https://doaj.org/article/ddffffb5080b4efba26d0571887e537d
Autor:
Bhavana S. Lakshmi, Naeha Subramanian, Ajay Suresh Akhade, Neha Dikshit, Ayub Qadri, Kelly T. Hughes, Shaikh M. Atif
Publikováno v:
Proceedings of the National Academy of Sciences. 117:29811-29822
Inflammasomes have been implicated in the detection and clearance of a variety of bacterial pathogens, but little is known about whether this innate sensing mechanism has any regulatory effect on the expression of stimulatory ligands by the pathogen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9b2c26541821c15a6ce8a47fa0794b3
https://doi.org/10.1073/pnas.2002747117
https://doi.org/10.1073/pnas.2002747117
Autor:
Ajay Suresh, Akhade, Shaikh M, Atif, Bhavana S, Lakshmi, Neha, Dikshit, Kelly T, Hughes, Ayub, Qadri, Naeha, Subramanian
Publikováno v:
Proc Natl Acad Sci U S A
Inflammasomes have been implicated in the detection and clearance of a variety of bacterial pathogens, but little is known about whether this innate sensing mechanism has any regulatory effect on the expression of stimulatory ligands by the pathogen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e87c5853e12277c71d9bbed538607aa6
https://pubmed.ncbi.nlm.nih.gov/33177235
https://pubmed.ncbi.nlm.nih.gov/33177235
Autor:
Thuan Tong Tan, Neha Dikshit, A L Kwa, C Y Tang, Hanif Javanmard Khameneh, Sandeep D. Kale, Vanniarajan Balamuralidhar, Bindu Sukumaran, T P Lim, Pankaj Kumar, Alessandra Mortellaro
Publikováno v:
Mucosal Immunology. 11:257-272
The opportunistic Gram-negative bacterium Acinetobacter baumannii (AB) is a leading cause of life-threatening nosocomial pneumonia. Outbreaks of multidrug resistant (MDR)-AB belonging to international clones (ICs) I and II with limited treatment opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be36f72579fafdb885fac84003745176
https://doi.org/10.1038/mi.2017.50
https://doi.org/10.1038/mi.2017.50
Autor:
Hanif Javanmard Khameneh, Thuan Tong Tan, Tse Hsien Koh, Sandeep D. Kale, Alessandra Mortellaro, Vanniarajan Balamuralidhar, Najib Bin Abdul Malik, Pankaj Kumar, Gladys Tan, Neha Dikshit, Bindu Sukumaran
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports
Scientific Reports
Acinetobacter baumannii (A. baumannii) is a significant cause of severe nosocomial pneumonia in immunocompromised individuals world-wide. With limited treatment options available, a better understanding of host immnity to A. baumannii infection is cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6f281bfca7f9775d3c290cc7b53900
http://link.springer.com/article/10.1038/s41598-017-17653-y
http://link.springer.com/article/10.1038/s41598-017-17653-y
Autor:
Ajay Suresh Akhade, Shaikh M Atif, Bhavna S Lakshmi, Neha Dikshit, Ayub Qadri, Naeha Subramanian
Publikováno v:
The Journal of Immunology. 204:226.12-226.12
While the effect of bacterial molecules on host immune system is well studied, how host factors affect expression of bacterial molecules is not understood in great detail. Inflammasomes are instrumental in detection and clearance of bacterial pathoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0571edd6255388f995d111f9d483a9f5
https://doi.org/10.4049/jimmunol.204.supp.226.12
https://doi.org/10.4049/jimmunol.204.supp.226.12
Autor:
Ramnik J. Xavier, Avinash R. Shenoy, Keh-Chuang Chin, Michelle Hong, Matija Hedl, Hanif Javanmard Khameneh, Clara Abraham, Pradeep Bist, Albert Neutzner, Alessandra Mortellaro, John D. MacMicking, Vanniarajan Balamuralidhar, Niyas Kudukkil Pulloor, Koichi Kobayashi, Najib Bin Abdul Malik, Wan Shoo Cheong, Antonio Bertoletti, Neha Dikshit, Bae Hoon Kim, Bindu Sukumaran, Aylwin Ng
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications
Nature Communications
Optimal regulation of the innate immune receptor nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is essential for controlling bacterial infections and inflammatory disorders. Chronic NOD2 stimulation induces non-responsiveness t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460a70ca5c17b4ba00ff764ae0c637c9
http://hdl.handle.net/10044/1/50102
http://hdl.handle.net/10044/1/50102
