Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Neha Attal"'
Autor:
Natalia A. Osna, Irina Tikhanovich, Martí Ortega-Ribera, Sebastian Mueller, Chaowen Zheng, Johannes Mueller, Siyuan Li, Sadatsugu Sakane, Raquel Carvalho Gontijo Weber, Hyun Young Kim, Wonseok Lee, Souradipta Ganguly, Yusuke Kimura, Xiao Liu, Debanjan Dhar, Karin Diggle, David A. Brenner, Tatiana Kisseleva, Neha Attal, Iain H. McKillop, Shilpa Chokshi, Ram Mahato, Karuna Rasineni, Gyongyi Szabo, Kusum K. Kharbanda
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 404 (2024)
Alcohol-associated liver disease (ALD) is a substantial cause of morbidity and mortality worldwide and represents a spectrum of liver injury beginning with hepatic steatosis (fatty liver) progressing to inflammation and culminating in cirrhosis. Mult
Externí odkaz:
https://doaj.org/article/142e2cdd280940af8c937a0c17615d54
Publikováno v:
Biology, Vol 11, Iss 11, p 1613 (2022)
Fatty acid binding protein-4 (FABP4) is not normally expressed in the liver but is induced in alcohol-dependent liver disease (ALD)). This study sought to identify mechanisms whereby ethanol (EtOH) metabolism alters triglyceride accumulation and FABP
Externí odkaz:
https://doaj.org/article/a7b40bb5175f4ac2b59faa900b5a4f88
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100975- (2021)
Fatty liver disease (hepatosteatosis) is a common early pathology in alcohol-dependent and obese patients. Fatty acid binding protein-4 (FABP4) is normally expressed in adipocytes and macrophages and functions as a regulator of intracellular lipid mo
Externí odkaz:
https://doaj.org/article/232791548c8e403aa350844032b4ebc9
Publikováno v:
Physiology. 38
Background. In healthy individuals hepatic lipid transport and storage is closely regulated via several integrated pathways, including a central role for fatty acid binding protein-1 (FABP1). Increased hepatic fat accumulation (non-alcoholic fatty li
Publikováno v:
Alcohol Clin Exp Res
Hepatic steatosis is an early pathology of alcohol-associated liver disease (ALD). Fatty acid-binding protein-4 (FABP4, a FABP not normally produced in the liver) is secreted by hepatocytes in ALD and stimulates hepatoma proliferation and migration.
Autor:
Emilio Marrero, Neha Attal, Ali Nimeri, Rachel M. McGee, Jennifer H. Benbow, Kyle J. Thompson, Laura W. Schrum, Iain H. McKillop
Publikováno v:
Experimental cell research. 419(2)
The interaction between activated hepatic stellate cells (aHSCs) and macrophages is central to liver fibrosis development. The cargo contained within aHSC exosomes (aHSC-EXOs) and how aHSC-EXOs affect macrophage function is poorly understood.RNA from
Autor:
Elizabeth Brandon-Warner, Nicole A. Feilen, Neha Attal, Laura W. Schrum, Rachel M. McGee, Jennifer H Benbow, Emilio Marrero, Iain H. McKillop, Catherine R. Culberson
Publikováno v:
Exp Cell Res
Background Hepatic stellate cell (HSC) differentiation/activation is central to liver fibrosis and is innately linked to the immune response to liver injury. Exosomes (EXOs) are important means of communication between cell populations. This study so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b2a28ca2d81afe7d8afca34de9ea7b
https://europepmc.org/articles/PMC8206040/
https://europepmc.org/articles/PMC8206040/
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100975-(2021)
Translational Oncology, Vol 14, Iss 1, Pp 100975-(2021)
Highlights • Fatty liver disease (hepatosteatosis) is a hallmark of ALD and NAFLD. • FABP4 is normally expressed in adipocytes and macrophages. • ALD leads to FABP4 synthesis/release from steatotic hepatocytes. • FABP4 stimulates hepatoma cel